Papers/PMID:24639423
Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI).
European heart journal2014The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
sodium nitrite — increases plasma nitrite concentration
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“Plasma nitrite [mean (SD), µmol/L] was similar at baseline [0.76 (0.14) vs. 0.73 (0.08)] but higher in the nitrite group 5 min after ceasing infusion [1.42 (0.96) vs. 0.18 (0.08); P = 0.008].”
Quoted verbatim from Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI).. - Study
- RCT
- Dose
- 70 umol sodium nitrite in 5 mL water, intravenous over 5 minutes
- Population
- Subset of patients with acute ST-elevation myocardial infarction having plasma nitrite sampled before and 5 minutes after a 5-minute intravenous infusion of sodium nitrite or saline placebo before primary PCI; 17-patient substudy (11 nitrite, 6 placebo), measured 5 minutes after infusion
Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI).2014PMID:24639423Permalink