Skip to content

Papers/PMID:21563143

Selenium for preventing cancer.

The Cochrane database of systematic reviews2011The record

2 findings · 1 compound · 2 endpoints · 1 null

What it reported

How to read these marks

What moved

1 finding

  • selenium atom — decreases urinary bladder cancer incidence

    Evidence strength: limited.Finding
    “Meta-analysis of bladder cancer incidence in five observational studies found an inverse association with an overall risk estimate of 0.67 (95% CI 0.46 to 0.97) suggesting a protective effect of higher selenium levels against bladder cancer (overall heterogeneity: I2 = 30%).”
    Quoted verbatim from Selenium for preventing cancer..
    Study
    meta-analysis
    Population
    adults free of cancer at baseline in five prospective observational studies, highest versus lowest category of baseline selenium exposure

    Selenium for preventing cancer.2011PMID:2156314310.1002/14651858.CD005195.pub2Permalink

What did not

1 finding

  • selenium atom — no detected effect on breast cancer incidence

    Evidence strength: moderate.FindingNull resultreplicated ×2
    “No association was seen between baseline selenium levels and incidence of breast cancer with an overall risk estimate of OR 1.00 (95% CI 0.78 to 1.29).”
    Quoted verbatim from Selenium for preventing cancer..
    Study
    meta-analysis
    Population
    adults free of cancer at baseline in seven prospective observational studies, highest versus lowest category of baseline selenium exposure

    Effect 1 odds ratio, 95% CI 0.78 to 1.29

    Selenium for preventing cancer.2011PMID:2156314310.1002/14651858.CD005195.pub2Permalink