Papers/PMID:21445287
Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
PloS one2011The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
selenium atom — no detected effect on glutathione peroxidase activity
Evidence strength: moderate.FindingNull result“However, there were no significant effects of Se-yeast dose or Se-enriched onions on erythrocyte GPx1 activity compared to the placebo and unenriched onion groups respectively.”
Quoted verbatim from Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.. - Study
- RCT
- Duration
- 3 months
- Dose
- 50, 100 or 200 ug Se/day as Se-yeast tablets; 50 ug Se/day in Se-enriched onion meals
- Population
- Adults aged 50-64 years with suboptimal selenium status (plasma Se below 110 ng/ml); Se-yeast tablets at 50, 100 or 200 ug/day each compared with placebo, and Se-enriched onion meals compared with unenriched onion meals, at week 12
Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.2011PMID:2144528710.1371/journal.pone.0014771Industry fundedPermalink