Skip to content
Catalyst
Search

Papers/PMID:19933175

I.V. infusion of magnesium sulphate during spinal anaesthesia improves postoperative analgesia.

British journal of anaesthesia2010The record

1 finding · 1 compound · 1 endpoint

What it reported

How to read these marks

What moved

1 finding

  • magnesium(2+) — increases serum magnesium concentration

    Evidence strength: very limited.Findingreplicated ×12
    “Postoperative magnesium concentrations were higher in Group M (P<0.05 at 4, 24, and 48 h after surgery), but no side-effects associated with hypermagnesemia were observed.”
    Quoted verbatim from I.V. infusion of magnesium sulphate during spinal anaesthesia improves postoperative analgesia..
    Study
    RCT
    Dose
    magnesium sulphate 50 mg/kg over 15 min then 15 mg/kg/h i.v. until end of surgery
    Population
    40 patients undergoing total hip replacement arthroplasty under spinal anaesthesia; saline infusion comparator; significant at 4, 24 and 48 h after surgery

    I.V. infusion of magnesium sulphate during spinal anaesthesia improves postoperative analgesia.2010PMID:1993317510.1093/bja/aep334Permalink