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PapersPMID:19584739

The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia.

International clinical psychopharmacology2009The record ↗

  1. Finding, very limited evidencelowersSleep onset latency

What moved

1 findingHow to read these marks →
  • Decreases sleep onset latency

    very limitedreplicated ×11

    “By the end of the double-blind treatment, the PRM group had significantly shorter sleep onset latency (9 min; P = 0.02) compared with the placebo group and scored significantly better in the Critical Flicker Fusion Test (P = 0.008) without negatively affecting sleep structure and architecture.”
    Study
    RCT
    Duration
    3 weeks
    Dose studied
    prolonged-release melatonin 2 mg nightly
    Population
    Adults aged 55 years and older with primary insomnia (DSM-IV)

Study record

Design
randomised controlled trial
Species
human
Population
Adults aged 55 years and older with primary insomnia (DSM-IV)
Participants
40
Comparator
placebo
Duration
21 days
Endpoints measured
4