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Papers/PMID:19199498

Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial.

Journal of neurosurgery2009The record

1 finding · 1 compound · 1 endpoint

What it reported

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What moved

1 finding

  • magnesium(2+) — increases serum magnesium concentration

    Evidence strength: moderate.Findingreplicated ×12
    “At all time points postinfusion, magnesium levels for patients treated with magnesium sulfate infusion were elevated when compared with those in the placebo group (p < 0.01 at all time points; Table 2).”
    Quoted verbatim from Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial..
    Study
    RCT
    Duration
    1 day
    Dose
    Intravenous magnesium sulfate: 100 ml loading dose over 25 minutes then 400 ml continuous infusion over 24 hours; three protocols differing in loading or infusion dose
    Population
    Patients undergoing elective carotid endarterectomy under general anesthesia, all three magnesium dosing protocols pooled versus saline placebo

    Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial.2009PMID:1919949810.3171/2008.9.17671Permalink