PapersPMID:15916468
Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans.
glycine betaineWhat moved
1 findingHow to read these marks →- Increases total cholesterol (TC)
moderate
“Supplementation of 6 g/d of betaine for 6 wk increased total cholesterol concentrations by 0.42 mmol/l (8%) relative to placebo (see Table 3).”
- Study
- RCT
- Duration
- 6 weeks
- Effect
- 0.42 mean difference
- Interests
- Industry funded
- Dose studied
- 6 g/d of betaine (BUFA) dissolved in water, half after breakfast and half after the evening meal
- Population
- Healthy adults with higher plasma homocysteine, combined weighted effect of betaine 6 g/d versus placebo from two parallel and one crossover placebo-controlled double-blind trials
Study record
- Design
- randomised controlled trial
- Species
- human
- Population
- healthy volunteers with the highest plasma total homocysteine concentrations, four placebo-controlled studies
- Participants
- not reported
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 11