Papers/PMID:15855241
Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials.
The Annals of pharmacotherapy2005The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
glucosamine — decreases osteoarthritis pain (pooled across scales)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“The pooled effect sizes for pain reduction and improvement in physical function were 0.41 (95% CI 0.21 to 0.60; p < 0.0001) and 0.46 (95% CI 0.27 to 0.66; p < 0.0001), respectively, in favor of glucosamine sulfate.”
Quoted verbatim from Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials.. - Study
- meta-analysis
- Dose
- glucosamine sulfate
- Population
- Knee osteoarthritis patients, long-term (at least 1 year) oral glucosamine sulfate trials, pooled
Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials.2005PMID:15855241Permalink
glucosamine — increases physical function (pooled across scales)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The pooled effect sizes for pain reduction and improvement in physical function were 0.41 (95% CI 0.21 to 0.60; p < 0.0001) and 0.46 (95% CI 0.27 to 0.66; p < 0.0001), respectively, in favor of glucosamine sulfate.”
Quoted verbatim from Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials.. - Study
- meta-analysis
- Dose
- glucosamine sulfate
- Population
- Knee osteoarthritis patients, long-term (at least 1 year) oral glucosamine sulfate trials, pooled
Glucosamine long-term treatment and the progression of knee osteoarthritis: systematic review of randomized controlled trials.2005PMID:15855241Permalink