Papers/PMID:15674878
Glutamine supplementation to prevent morbidity and mortality in preterm infants.
The Cochrane database of systematic reviews2005The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
L-glutamine — no detected effect on necrotising enterocolitis incidence
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“We found that glutamine supplementation does not have a statistically significant effect on the incidence of systemic infection (typical relative risk 1.02 (95% confidence interval 0.92 to 1.13); typical risk difference 0.01 (95% confidence interval -0.03 to 0.05)), necrotising enterocolitis (typical relative risk 1.02 (95% confidence interval 0.79 to 1.33); typical risk difference 0.00 (95% confidence interval -0.02 to 0.03)), days to full enteral nutrition (weighted mean difference -1.1 days (95% confidence interval -3.4 to 1.2)), or duration of hospital stay (weighted mean difference 0.65 days (95% confidence interval -2.9 to 4.2)).”
Quoted verbatim from Glutamine supplementation to prevent morbidity and mortality in preterm infants.. - Study
- meta-analysis
- Population
- very low birth weight preterm infants (pooled meta-analysis of six randomised trials, enteral and parenteral)
Effect 1.02 risk ratio, 95% CI 0.79 to 1.33
Glutamine supplementation to prevent morbidity and mortality in preterm infants.2005PMID:15674878Permalink
L-glutamine — no detected effect on hospital length of stay
PreliminaryGrade D, Preliminary. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull resultreplicated ×1“We found that glutamine supplementation does not have a statistically significant effect on the incidence of systemic infection (typical relative risk 1.02 (95% confidence interval 0.92 to 1.13); typical risk difference 0.01 (95% confidence interval -0.03 to 0.05)), necrotising enterocolitis (typical relative risk 1.02 (95% confidence interval 0.79 to 1.33); typical risk difference 0.00 (95% confidence interval -0.02 to 0.03)), days to full enteral nutrition (weighted mean difference -1.1 days (95% confidence interval -3.4 to 1.2)), or duration of hospital stay (weighted mean difference 0.65 days (95% confidence interval -2.9 to 4.2)).”
Quoted verbatim from Glutamine supplementation to prevent morbidity and mortality in preterm infants.. - Study
- meta-analysis
- Population
- very low birth weight preterm infants (pooled meta-analysis of six randomised trials, enteral and parenteral)
Effect 0.65 mean difference, 95% CI -2.9 to 4.2
Glutamine supplementation to prevent morbidity and mortality in preterm infants.2005PMID:15674878Permalink