Skip to content
Catalyst

PapersPMID:15674878

Glutamine supplementation to prevent morbidity and mortality in preterm infants.

The Cochrane database of systematic reviews2005The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, very limited evidenceno difference foundNecrotising enterocolitis incidence
  2. Finding, very limited evidenceno difference foundHospital length of stay
Study, every finding
meta-analysis
Population, every finding
very low birth weight preterm infants (pooled meta-analysis of six randomised trials, enteral and parenteral)

No finding here moved its endpoint.

  • “We found that glutamine supplementation does not have a statistically significant effect on the incidence of systemic infection (typical relative risk 1.02 (95% confidence interval 0.92 to 1.13); typical risk difference 0.01 (95% confidence interval -0.03 to 0.05)), necrotising enterocolitis (typical relative risk 1.02 (95% confidence interval 0.79 to 1.33); typical risk difference 0.00 (95% confidence interval -0.02 to 0.03)), days to full enteral nutrition (weighted mean difference -1.1 days (95% confidence interval -3.4 to 1.2)), or duration of hospital stay (weighted mean difference 0.65 days (95% confidence interval -2.9 to 4.2)).”

Study record

Design
meta-analysis
Species
human
Population
very low birth weight preterm infants, birth to hospital discharge (pooled meta-analysis of six randomised trials, enteral and parenteral)
Participants
2,300
Comparator
not stated in the paper
Duration
not reported
Endpoints measured
6