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Catalyst

L-glutamineFinding

L-glutamine has no detected effect on necrotising enterocolitis incidence

no difference foundVery limited evidenceFinding

01 · The sentence it was drawn from

“We found that glutamine supplementation does not have a statistically significant effect on the incidence of systemic infection (typical relative risk 1.02 (95% confidence interval 0.92 to 1.13); typical risk difference 0.01 (95% confidence interval -0.03 to 0.05)), necrotising enterocolitis (typical relative risk 1.02 (95% confidence interval 0.79 to 1.33); typical risk difference 0.00 (95% confidence interval -0.02 to 0.03)), days to full enteral nutrition (weighted mean difference -1.1 days (95% confidence interval -3.4 to 1.2)), or duration of hospital stay (weighted mean difference 0.65 days (95% confidence interval -2.9 to 4.2)).”
Quoted verbatim from Glutamine supplementation to prevent morbidity and mortality in preterm infants.
This finding among the 8 findings on its endpoint

L-glutamine

Necrotising enterocolitis incidence

no difference found

Effect as reported

1.02risk ratio

CI 0.79 to 1.33

Who
very low birth weight preterm infants (pooled meta-analysis of six randomised trials, enteral and parenteral)
Dose studied
not reported

Very limited evidencePMID 15674878 · 2005

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

The Cochrane database of systematic reviews
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M38TYN5WCMQFFE9D063BNT7R