Papers/PMID:15277288
Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.
Archives of internal medicine2004The record
3 findings · 1 compound · 3 endpoints · 3 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
3 findings
α-tocopherol — no detected effect on cardiovascular mortality
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“In an overview, vitamin E had neither a statistically significant nor a clinically important effect on any important cardiovascular event (odds ratio [OR], 0.98; 95% confidence interval [CI], 0.94-1.03) or its components: nonfatal myocardial infarction (OR, 1.00; 95% CI, 0.92-1.09), nonfatal stroke (OR, 1.03; 95% CI, 0.93-1.14), or cardiovascular death (OR, 1.00; 95% CI, 0.94-1.05).”
Quoted verbatim from Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.. - Study
- meta-analysis
- Population
- Participants in 7 large-scale randomized trials of vitamin E for treatment and prevention of cardiovascular disease
Effect 1 odds ratio, 95% CI 0.94 to 1.05
Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.2004PMID:15277288Permalink
α-tocopherol — no detected effect on incidence of myocardial infarction
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“In an overview, vitamin E had neither a statistically significant nor a clinically important effect on any important cardiovascular event (odds ratio [OR], 0.98; 95% confidence interval [CI], 0.94-1.03) or its components: nonfatal myocardial infarction (OR, 1.00; 95% CI, 0.92-1.09), nonfatal stroke (OR, 1.03; 95% CI, 0.93-1.14), or cardiovascular death (OR, 1.00; 95% CI, 0.94-1.05).”
Quoted verbatim from Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.. - Study
- meta-analysis
- Population
- Participants in 7 large-scale randomized trials of vitamin E for treatment and prevention of cardiovascular disease
Effect 1 odds ratio, 95% CI 0.92 to 1.09
Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.2004PMID:15277288Permalink
α-tocopherol — no detected effect on incidence of stroke
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull resultreplicated ×1“In an overview, vitamin E had neither a statistically significant nor a clinically important effect on any important cardiovascular event (odds ratio [OR], 0.98; 95% confidence interval [CI], 0.94-1.03) or its components: nonfatal myocardial infarction (OR, 1.00; 95% CI, 0.92-1.09), nonfatal stroke (OR, 1.03; 95% CI, 0.93-1.14), or cardiovascular death (OR, 1.00; 95% CI, 0.94-1.05).”
Quoted verbatim from Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.. - Study
- meta-analysis
- Population
- Participants in 7 large-scale randomized trials of vitamin E for treatment and prevention of cardiovascular disease
Effect 1.03 odds ratio, 95% CI 0.93 to 1.14
Randomized trials of vitamin E in the treatment and prevention of cardiovascular disease.2004PMID:15277288Permalink