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PapersPMID:11211063

A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome.

Psychosomatic medicine2001The record ↗

  1. Finding, very limited evidencelowersSleep onset latency

What moved

1 findingHow to read these marks →
  • Decreases sleep onset latency

    very limitedreplicated ×11

    “In the 20 patients who completed the study, sleep onset latency was significantly reduced while subjects were taking melatonin as compared with both placebo and baseline.”
    Study
    crossover
    Participants
    20
    Duration
    4 weeks
    Dose studied
    melatonin 5 mg, taken 19:00-21:00
    Population
    22 patients (20 completed) with delayed sleep phase syndrome, nocturnal sleep restricted to 24:00-08:00, polysomnography

Study record

Design
crossover trial
Species
human
Population
22 patients with delayed sleep phase syndrome, nocturnal sleep restricted to 24:00-08:00 (20 completed)
Participants
22
Comparator
placebo
Duration
28 days
Endpoints measured
4