PapersPMID:11211063
A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome.
What moved
1 findingHow to read these marks →- Decreases sleep onset latency
very limitedreplicated ×11
“In the 20 patients who completed the study, sleep onset latency was significantly reduced while subjects were taking melatonin as compared with both placebo and baseline.”
- Study
- crossover
- Participants
- 20
- Duration
- 4 weeks
- Dose studied
- melatonin 5 mg, taken 19:00-21:00
- Population
- 22 patients (20 completed) with delayed sleep phase syndrome, nocturnal sleep restricted to 24:00-08:00, polysomnography
Study record
- Design
- crossover trial
- Species
- human
- Population
- 22 patients with delayed sleep phase syndrome, nocturnal sleep restricted to 24:00-08:00 (20 completed)
- Participants
- 22
- Comparator
- placebo
- Duration
- 28 days
- Endpoints measured
- 4
melatonin