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Subsystem: Lysine metabolism Remove
42 reactions in Lysine metabolism
3-hydroxy-N6,N6,N6-trimethyl-L-lysine[m] + H+[m] = 4-trimethylammoniobutanal[m] + glycine[m]
Left to rightBalancedEC 2.1.2.1Human-GEM MAR01371
H+[n] + histone-N6-methyl-L-lysine[n] + SAH[n] = histone-L-lysine[n] + SAM[n]
ReversibleBalance undeterminableEC 2.1.1.354Human-GEM MAR04241
AKG[m] + H+[m] + lysine[m] + NADPH[m] = H2O[m] + NADP+[m] + saccharopine[m]
Left to rightBalancedEC 1.5.1.8Human-GEM MAR04288
2-oxoadipate[c] + glutamate[c] = AKG[c] + L-2-aminoadipate[c]
ReversibleBalancedEC 2.6.1.39Human-GEM MAR04596
2-oxoadipate[m] + glutamate[m] = AKG[m] + L-2-aminoadipate[m]
Reversible
lipoamide[m] + 2-(4-carboxy-1-hydroxybutyl)thiamine diphosphate[m] = S-glutaryldihydrolipoamide[m] + thiamin-PP[m]
Left to rightBalance undeterminableEC 1.2.4.2Human-GEM MAR04599
H2O[m] + NAD+[m] + saccharopine[m] = 2-aminoadipate 6-semialdehyde[m] + glutamate[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.5.1.9Human-GEM MAR04667
H2O[m] + NADP+[m] + saccharopine[m] = 2-aminoadipate 6-semialdehyde[m] + glutamate[m] + H+[m] + NADPH[m]
Left to rightBalancedEC 1.5.1.10Human-GEM MAR04668
2-aminoadipate 6-semialdehyde[c] + H2O[c] + NAD+[c] = 2 H+[c] + L-2-aminoadipate[c] + NADH[c]
Left to rightBalancedEC 1.2.1.31Human-GEM MAR04737
2-aminoadipate 6-semialdehyde[m] + H2O[m] + NAD+[m] = 2 H+[m] + L-2-aminoadipate[m] + NADH[m]
Left to rightBalancedEC 1.2.1.31Human-GEM MAR04739
1-piperideine-6-carboxylate[c] + H+[c] + H2O[c] = 2-aminoadipate 6-semialdehyde[c]
ReversibleBalancedEC 1.14.17.1Human-GEM MAR04740
CoA[m] + S-glutaryldihydrolipoamide[m] = dihydrolipoamide[m] + glutaryl-CoA[m]
Left to rightBalancedEC 2.3.1.61Human-GEM MAR06415
[protein][c] + lysine[c] = [protein]-L-lysine[c] + H2O[c]
Left to rightBalance undeterminableHuman-GEM MAR06974
[protein]-L-lysine[c] + SAM[c] = [protein]-N6-methyl-L-lysine[c] + H+[c] + SAH[c]
Left to rightBalance undeterminableEC 2.1.1.354Human-GEM MAR06975
[protein]-N6-methyl-L-lysine[c] + SAM[c] = [protein]-N6,N6-dimethyl-L-lysine[c] + H+[c] + SAH[c]
Left to rightBalance undeterminableEC 2.1.1.354Human-GEM MAR06976
[protein]-N6,N6-dimethyl-L-lysine[c] + SAM[c] = [protein]-N6,N6,N6-trimethyl-L-lysine[c] + H+[c] + SAH[c]
Left to rightBalance undeterminableEC 2.1.1.354Human-GEM MAR06977
[protein]-N6,N6,N6-trimethyl-L-lysine[c] + H2O[c] = [protein][c] + H+[c] + N6,N6,N6-trimethyl-L-lysine[c]
Left to rightBalance undeterminableEC 3.4.21.89, 3.4.-.-Human-GEM MAR06978
AKG[c] + N6,N6,N6-trimethyl-L-lysine[c] + O2[c] = 3-hydroxy-N6,N6,N6-trimethyl-L-lysine[c] + CO2[c] + succinate[c]
Left to rightBalancedEC 1.14.11.8Human-GEM MAR06979
3-hydroxy-N6,N6,N6-trimethyl-L-lysine[c] + H+[c] = 4-trimethylammoniobutanal[c] + glycine[c]
Left to rightBalancedEC 2.1.2.1Human-GEM MAR06980
4-trimethylammoniobutanal[c] + H2O[c] + NAD+[c] = gamma-butyrobetaine[c] + 2 H+[c] + NADH[c]
Left to rightBalancedEC 1.2.1.47Human-GEM MAR06981
AKG[c] + gamma-butyrobetaine[c] + O2[c] = CO2[c] + L-carnitine[c] + succinate[c]
Left to rightBalancedEC 1.14.11.1Human-GEM MAR06982
[protein]-L-lysine[c] + AKG[c] + O2[c] = CO2[c] + procollagen-5-hydroxy-L-lysine[c] + succinate[c]
Left to rightBalance undeterminableEC 1.14.11.4Human-GEM MAR06983
procollagen-5-hydroxy-L-lysine[c] + UDP-galactose[c] = 5-(D-galactosyloxy)-L-lysine-procollagen[c] + H+[c] + UDP[c]
Left to rightBalance undeterminableEC 2.4.1.50Human-GEM MAR06984
5-(D-galactosyloxy)-L-lysine-procollagen[c] + UDP-glucose[c] = 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen[c] + H+[c] + UDP[c]
Left to rightBalance undeterminableEC 2.4.1.66Human-GEM MAR06985
FAD[x] + H2O[x] + lysine[x] = 6-amino-2-oxohexanoate[x] + FADH2[x] + H+[x] + NH3[x]
Left to rightBalancedHuman-GEM MAR08017
6-amino-2-oxohexanoate[x] = delta1-piperideine-2-carboxylate[x] + H2O[x]
Left to rightBalancedHuman-GEM MAR08018
delta1-piperideine-2-carboxylate[x] + H+[x] + NADH[x] = L-pipecolate[x] + NAD+[x]
Left to rightBalancedHuman-GEM MAR08019
FAD[x] + L-pipecolate[x] = 1-piperideine-6-carboxylate[x] + FADH2[x] + H+[x]
Left to rightBalancedEC 1.5.3.1, 1.5.3.7Human-GEM MAR08021
[protein]-L-lysine[n] + SAM[n] = H+[n] + histone-N6-methyl-L-lysine[n] + SAH[n]
Left to rightBalance undeterminableEC 2.1.1.354Human-GEM MAR08025
histone-N6-methyl-L-lysine[n] + SAM[n] = [protein]-N6,N6-dimethyl-L-lysine[n] + H+[n] + SAH[n]
Left to rightBalance undeterminableEC 2.1.1.354Human-GEM MAR08026
[protein]-N6,N6-dimethyl-L-lysine[n] + SAM[n] = [protein]-N6,N6,N6-trimethyl-L-lysine[n] + H+[n] + SAH[n]
Left to rightBalance undeterminableEC 2.1.1.354Human-GEM MAR08027
[protein]-N6,N6,N6-trimethyl-L-lysine[r] + H2O[r] = [protein][r] + H+[r] + N6,N6,N6-trimethyl-L-lysine[r]
Left to rightBalance undeterminableEC 3.4.21.89, 3.4.-.-Human-GEM MAR08029
2-oxoadipate[c] + H+[c] + NADH[c] = NAD+[c] + 2-hydroxyadipic acid[c]
ReversibleBalancedEC 1.1.1.172Human-GEM MAR09935
carbamoyl-phosphate[c] + lysine[c] = H+[c] + Pi[c] + Homocitrulline[c]
ReversibleBalancedEC 2.1.3.8Human-GEM MAR09940
H2O[c] + Acetyl-L-Lysine[c] = acetate[c] + lysine[c]
ReversibleBalancedEC 3.5.1.17Human-GEM MAR09952
acetyl-CoA[m] + lysine[m] = CoA[m] + H+[m] + Acetyl-L-Lysine[m]
Left to rightBalancedHuman-GEM MAR10358
FAD[m] + glutaryl-CoA[m] = FADH2[m] + trans-delta-2-glutaryl-CoA[m]
Left to rightBalancedHuman-GEM MAR11513
H2O[m] + trans-delta-2-glutaryl-CoA[m] = 3-hydroxy-glutaryl-CoA[m]
Left to rightBalancedEC 4.2.1.-Human-GEM MAR11514
H2O[m] + 3-hydroxy-glutaryl-CoA[m] = CoA[m] + H+[m] + 3-Hydroxy-Glutarate[m]
Left to rightBalancedHuman-GEM MAR11515
FAD[m] + glutaryl-CoA[m] = FADH2[m] + glutaconyl-CoA[m]
Left to rightBalancedHuman-GEM MAR11520
H2O[m] + glutaconyl-CoA[m] = CoA[m] + H+[m] + Glutaconate[m]
Left to rightBalancedHuman-GEM MAR11521
2-oxoadipate[m] + H+[m] + thiamin-PP[m] = CO2[m] + 2-(4-carboxy-1-hydroxybutyl)thiamine diphosphate[m]
Left to rightBalance undeterminableEC 1.2.4.-Human-GEM MAR20173