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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

3,451–3,500 of 18,558 reactions from Rhea

sulcatol + NAD(+) = sulcatone + NADH + H(+)
Direction not assertedBalancedRhea 24484
isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)
Direction not assertedBalance undeterminableRhea 24488
4-O-deacetylvindoline + acetyl-CoA = vindoline + CoA
Direction not assertedBalancedRhea 24496
adenosine 5'-tetraphosphate + H2O = phosphate + ATP + H(+)
Left to rightBalancedRhea 24500
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)
Direction not assertedBalancedRhea 24504
prostaglandin F2alpha + NADP(+) = prostaglandin E2 + NADPH + H(+)
Right to leftBalancedRhea 24508
pyrazole + L-serine = 3-(pyrazol-1-yl)-L-alanine + H2O

Direction not assertedBalancedRhea 24512

gentamicin C1a + acetyl-CoA = N(2')-acetylgentamicin C1a + CoA + H(+)

Direction not assertedBalancedRhea 24516

L-saccharopine + NAD(+) + H2O = (S)-2-amino-6-oxohexanoate + L-glutamate + NADH + H(+)

Left to rightBalancedRhea 24520

20-oxo-5-O-beta-D-mycaminosyltylonolide + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 5-O-beta-D-mycaminosyltylonolide + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 24524

(R)-lactaldehyde + NAD(+) = methylglyoxal + NADH + H(+)

Direction not assertedBalancedRhea 24528

L-tryptophan + O2 = N-formyl-L-kynurenine

Direction not assertedBalancedRhea 24536

D-glucose + A = D-glucono-1,5-lactone + AH2

Direction not assertedBalancedRhea 24540

L-lysyl-[protein] + O2 + H2O = (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+)

Direction not assertedBalance undeterminableRhea 24544

an N(6)-acyl-L-lysine + H2O = a carboxylate + L-lysine

Direction not assertedBalance undeterminableRhea 24548

5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + NADPH + H(+)

Direction not assertedBalancedRhea 24552

5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H(+)

Direction not assertedBalancedRhea 24556

L-serine + acetyl-CoA = O-acetyl-L-serine + CoA

Direction not assertedBalancedRhea 24560

a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate

Left to rightBalance undeterminableRhea 24564

a 6-phospho-beta-D-galactoside + H2O = D-galactose 6-phosphate + an alcohol

Direction not assertedBalance undeterminableRhea 24568

[(1->4)-alpha-D-glucosyl](n) + sucrose = [(1->4)-alpha-D-glucosyl](n+1) + D-fructose

Direction not assertedBalance undeterminableRhea 24572

diphosphate + H2O = 2 phosphate + H(+)

Left to rightBalancedRhea 24576

D-sorbitol 6-phosphate + H2O = D-sorbitol + phosphate

Direction not assertedBalancedRhea 24580

D-arabinose + ATP = D-arabinose 5-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 24588

phosphoethanolamine + CTP + H(+) = CDP-ethanolamine + diphosphate

Left to rightBalancedRhea 24592

L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+)

Direction not assertedBalancedRhea 24596

sulfite + O2 + H2O = sulfate + H2O2

Left to rightBalancedRhea 24600

7-methylxanthine + S-adenosyl-L-methionine = theobromine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 24604

5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO2 + H2O

Direction not assertedBalancedRhea 24608

17beta-estradiol + NAD(+) = estrone + NADH + H(+)

ReversibleBalancedRhea 24612

17beta-estradiol + NADP(+) = estrone + NADPH + H(+)

Right to leftBalancedRhea 24616

octan-1-ol + NAD(+) = octanal + NADH + H(+)

Direction not assertedBalancedRhea 24620

tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 24624

NH4(+) + 3 NAD(+) + 2 H2O = nitrite + 3 NADH + 5 H(+)

Direction not assertedBalancedRhea 24628

NH4(+) + 3 NADP(+) + 2 H2O = nitrite + 3 NADPH + 5 H(+)

Direction not assertedBalancedRhea 24632

H2 + NAD(+) = NADH + H(+)

Direction not assertedBalancedRhea 24636

ergosteryl 3-beta-D-glucoside + H2O = ergosterol + D-glucose

Direction not assertedBalancedRhea 24640

L-arginine + NADPH + O2 + H(+) = N(omega)-hydroxy-L-arginine + NADP(+) + H2O

Direction not assertedBalancedRhea 24660

2 N(omega)-hydroxy-L-arginine + NADPH + 2 O2 = 2 L-citrulline + 2 nitric oxide + NADP(+) + 2 H2O + H(+)

Direction not assertedBalancedRhea 24664

hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)

Direction not assertedBalancedRhea 24670

cytidine + ATP = CMP + ADP + H(+)

Direction not assertedBalancedRhea 24674

5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylenetetrahydromethanopterin + H2O

Direction not assertedBalancedRhea 24678

5,10-methylenetetrahydromethanopterin + NADP(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH

Direction not assertedBalancedRhea 24682

N-formylmethanofuran + H2O = methanofuran + formate

Direction not assertedBalancedRhea 24686

eugenol + acetate + NADP(+) = (E)-coniferyl acetate + NADPH

Direction not assertedBalancedRhea 24690

(E)-isoeugenol + acetate + NADP(+) = (E)-coniferyl acetate + NADPH

Direction not assertedBalancedRhea 24694

alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 24698

UDP-alpha-D-glucuronate + NAD(+) = UDP-beta-L-threo-pentopyranos-4-ulose + CO2 + NADH

Direction not assertedBalancedRhea 24702

UDP-4-amino-4-deoxy-beta-L-arabinose + (6R)-10-formyltetrahydrofolate = UDP-4-deoxy-4-formamido-beta-L-arabinose + (6S)-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalancedRhea 24706

UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate

Direction not assertedBalancedRhea 24710

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