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3,451–3,500 of 12,877 reactions from Human-GEM
3(S)-hydroxy-4-methyl-pentanoyl-CoA[m] + NAD+[m] = 3-oxo-4-methyl-pentanoyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03533
3-oxo-4-methyl-pentanoyl-CoA[m] + CoA[m] = acetyl-CoA[m] + isobutyryl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Beta oxidation of branched-chain fatty acids (mitochondrial)Human-GEM MAR03534
3(S)-hydroxy-tetracosa-12,15,18,21-all-cis-tetraenoyl-CoA[r] = H2O[r] + trans,cis,cis,cis,cis-2,12,15,18,21-tetracosapentaenoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03535
3 24,25-dihydrolanosterol[c] + CO2[c] = 2 H2O[c] + 3 4,4-Dimethylcholesta-8(9),14-Dien-3Beta-Ol[c] + 4 One Carbon Unit[c]
Reversible
cholesterol-ester plasma pool[l] = 0.0001 cholesterol-ester-10,13,16,19-docosa[l] + 0.0001 cholesterol-ester-10,13,16-docosa[l] + 0.0001 cholesterol-ester-10-hepta[l] + 0.0001 cholesterol-ester-11,14,17-eico[l] + 0.0001 cholesterol-ester-11,14-eicosa[l] + 0.0001 cholesterol-ester-11-docose[l] + 0.0001 cholesterol-ester-11-eico[l] + 0.0001 cholesterol-ester-12,15,18,21-tetracosa[l] + 0.0001 cholesterol-ester-13,16,19-doco[l] + 0.0001 cholesterol-ester-13,16-docosa[l] + 0.0001 cholesterol-ester-13-docose[l] + 0.0001 cholesterol-ester-13-eicose[l] + 0.0001 cholesterol-ester-13-octade[l] + 0.0001 cholesterol-ester-15-tetra[l] + 0.0041 cholesterol-ester-4,7,10,13,16,19-doco[l] + 0.0001 cholesterol-ester-4,7,10,13,16-docosa[l] + 0.0071 cholesterol-ester-5,8,11,14,17-eico[l] + 0.0001 cholesterol-ester-5,8,11-eico[l] + 0.0001 cholesterol-ester-5-tetra[l] + 0.0001 cholesterol-ester-6,9,12,15,18,21-tetra[l] + 0.0001 cholesterol-ester-6,9,12,15,18-tetraco[l] + 0.0001 cholesterol-ester-6,9,12,15-octa[l] + 0.0001 cholesterol-ester-6,9-octa[l] + 0.0001 cholesterol-ester-7,10,13,16,19-docosa[l] + 0.0001 cholesterol-ester-7,10,13,16-docosa[l] + 0.0406 cholesterol-ester-7-hexa[l] + 0.0001 cholesterol-ester-7-octade[l] + 0.0001 cholesterol-ester-7-tetrade[l] + 0.0001 cholesterol-ester-8,11,14,17-eico[l] + 0.0001 cholesterol-ester-8,11-eico[l] + 0.0001 cholesterol-ester-9,12,15,18,21-tetra[l] + 0.0001 cholesterol-ester-9,12,15,18-tetraco[l] + 0.0001 cholesterol-ester-9-eicose[l] + 0.0001 cholesterol-ester-9-heptade[l] + 0.0001 cholesterol-ester-9-octa[l] + 0.0001 cholesterol-ester-9-tetrade[l] + 0.0518 cholesterol-ester-arach[l] + 0.0001 cholesterol-ester-cis-vac[l] + 0.005 cholesterol-ester-dihomo-gamma[l] + 0.0001 cholesterol-ester-docosa[l] + 0.0001 cholesterol-ester-eico[l] + 0.0001 cholesterol-ester-gamma-lin[l] + 0.0001 cholesterol-ester-heneico[l] + 0.0001 cholesterol-ester-hepta[l] + 0.0001 cholesterol-ester-hexacosa[l] + 0.0001 cholesterol-ester-hexecose[l] + 0.0001 cholesterol-ester-laur[l] + 0.5254 cholesterol-ester-lin[l] + 0.0061 cholesterol-ester-linolen[l] + 0.0081 cholesterol-ester-myrist[l] + 0.0001 cholesterol-ester-nanode[l] + 0.1958 cholesterol-ester-ol[l] + 0.138 cholesterol-ester-palm[l] + 0.0001 cholesterol-ester-palmn[l] + 0.0001 cholesterol-ester-penta[l] + 0.0132 cholesterol-ester-stea[l] + 0.0001 cholesterol-ester-tetraco[l] + 0.0001 cholesterol-ester-trico[l] + 0.0001 cholesterol-ester-tridec[l]
Left to rightBalance undeterminableFormation and hydrolysis of cholesterol estersHuman-GEM MAR03537
cholesterol-ester-laur[l] + H2O[l] = cholesterol[l] + H+[l] + lauric acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03538
cholesterol-ester-tridec[l] + H2O[l] = cholesterol[l] + H+[l] + tridecylic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03539
cholesterol-ester-myrist[l] + H2O[l] = cholesterol[l] + H+[l] + myristic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03540
cholesterol-ester-9-tetrade[l] + H2O[l] = (9E)-tetradecenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03541
cholesterol-ester-7-tetrade[l] + H2O[l] = (7Z)-tetradecenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03542
cholesterol-ester-5-tetra[l] + H2O[l] = cholesterol[l] + H+[l] + physeteric acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03543
cholesterol-ester-penta[l] + H2O[l] = cholesterol[l] + H+[l] + pentadecylic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03544
cholesterol-ester-palm[l] + H2O[l] = cholesterol[l] + H+[l] + palmitate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03545
cholesterol-ester-7-hexa[l] + H2O[l] = 7-palmitoleic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03546
cholesterol-ester-palmn[l] + H2O[l] = cholesterol[l] + H+[l] + palmitolate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03547
cholesterol-ester-hepta[l] + H2O[l] = cholesterol[l] + H+[l] + margaric acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03548
cholesterol-ester-10-hepta[l] + H2O[l] = (10Z)-heptadecenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03549
cholesterol-ester-9-heptade[l] + H2O[l] = 9-heptadecylenic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03550
cholesterol-ester-stea[l] + H2O[l] = cholesterol[l] + H+[l] + stearate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03551
cholesterol-ester-ol[l] + H2O[l] = cholesterol[l] + H+[l] + oleate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03552
cholesterol-ester-13-octade[l] + H2O[l] = (13Z)-octadecenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03553
cholesterol-ester-cis-vac[l] + H2O[l] = cholesterol[l] + cis-vaccenic acid[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03554
cholesterol-ester-9-octa[l] + H2O[l] = cholesterol[l] + elaidate[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03555
cholesterol-ester-7-octade[l] + H2O[l] = (7Z)-octadecenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03556
cholesterol-ester-6,9-octa[l] + H2O[l] = (6Z,9Z)-octadecadienoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03557
cholesterol-ester-nanode[l] + H2O[l] = cholesterol[l] + H+[l] + nonadecylic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03558
cholesterol-ester-eico[l] + H2O[l] = cholesterol[l] + eicosanoate[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03559
cholesterol-ester-13-eicose[l] + H2O[l] = (13Z)-eicosenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03560
cholesterol-ester-11-eico[l] + H2O[l] = cholesterol[l] + cis-gondoic acid[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03561
cholesterol-ester-9-eicose[l] + H2O[l] = 9-eicosenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03562
cholesterol-ester-8,11-eico[l] + H2O[l] = 8,11-eicosadienoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03563
cholesterol-ester-5,8,11-eico[l] + H2O[l] = cholesterol[l] + H+[l] + mead acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03564
cholesterol-ester-heneico[l] + H2O[l] = cholesterol[l] + H+[l] + heneicosanoic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03565
cholesterol-ester-docosa[l] + H2O[l] = behenic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03566
cholesterol-ester-13-docose[l] + H2O[l] = cholesterol[l] + cis-erucic acid[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03567
cholesterol-ester-11-docose[l] + H2O[l] = cholesterol[l] + cis-cetoleic acid[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03568
cholesterol-ester-trico[l] + H2O[l] = cholesterol[l] + H+[l] + tricosanoic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03569
cholesterol-ester-tetraco[l] + H2O[l] = cholesterol[l] + H+[l] + lignocerate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03570
cholesterol-ester-15-tetra[l] + H2O[l] = cholesterol[l] + H+[l] + nervonic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03571
cholesterol-ester-hexacosa[l] + H2O[l] = cerotic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03572
cholesterol-ester-hexecose[l] + H2O[l] = cholesterol[l] + H+[l] + ximenic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03573
cholesterol-ester-linolen[l] + H2O[l] = cholesterol[l] + H+[l] + linolenate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03574
cholesterol-ester-6,9,12,15-octa[l] + H2O[l] = cholesterol[l] + H+[l] + stearidonic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03575
cholesterol-ester-8,11,14,17-eico[l] + H2O[l] = cholesterol[l] + H+[l] + omega-3-arachidonic acid[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03576
cholesterol-ester-5,8,11,14,17-eico[l] + H2O[l] = cholesterol[l] + EPA[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03577
cholesterol-ester-7,10,13,16,19-docosa[l] + H2O[l] = cholesterol[l] + DPA[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03578
cholesterol-ester-9,12,15,18,21-tetra[l] + H2O[l] = (9Z,12Z,15Z,18Z,21Z)-TPA[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03579
cholesterol-ester-6,9,12,15,18,21-tetra[l] + H2O[l] = (6Z,9Z,12Z,15Z,18Z,21Z)-THA[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03580
cholesterol-ester-4,7,10,13,16,19-doco[l] + H2O[l] = cholesterol[l] + DHA[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03581
cholesterol-ester-11,14,17-eico[l] + H2O[l] = (11Z,14Z,17Z)-eicosatrienoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03582