Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

29,801–29,850 of 31,435, by identifier

2,4,6-trinitrotoluene + 2 NADPH + 2 H(+) = 2-hydroxylamino-4,6-dinitrotoluene + 2 NADP(+) + H2O
Direction not assertedBalancedRhea 80099
2,4,6-trinitrotoluene + 2 NADPH + 2 H(+) = 4-hydroxylamino-2,6-dinitrotoluene + 2 NADP(+) + H2O
Direction not assertedBalancedRhea 80103
2-hydroxylamino-4,6-dinitrotoluene + NADPH + H(+) = 2-amino-4,6-dinitrotoluene + NADP(+) + H2O
Direction not assertedBalancedRhea 80107
4-hydroxylamino-2,6-dinitrotoluene + NADPH + H(+) = 4-amino-2,6-dinitrotoluene + NADP(+) + H2O
Direction not assertedBalancedRhea 80111
4-hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H(+) = 2,4-dihydroxylamino-6-nitrotoluene + 2 NADP(+) + H2O
Direction not assertedBalancedRhea 80115
a ganglioside GA1 (d18:1(4E)) + 3'-phosphoadenylyl sulfate = a ganglioside SM1a (d18:1(4E)) + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalance undeterminable

Rhea 80119

a ganglioside SM1a (d18:1(4E)) + 3'-phosphoadenylyl sulfate = a ganglioside SB1a (d18:1(4E)) + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 80123

a ganglioside GA1 (d18:1(4E)) + 3'-phosphoadenylyl sulfate = a ganglioside SM1b (d18:1(4E)) + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 80127

nitroglycerin + NADPH = 1,2-dinitroglycerol + nitrite + NADP(+)

Direction not assertedBalancedRhea 80131

nitroglycerin + NADPH = 1,3-dinitroglycerol + nitrite + NADP(+)

Direction not assertedBalancedRhea 80135

1,2-dinitroglycerol + NADPH = 2-nitroglycerol + nitrite + NADP(+)

Direction not assertedBalancedRhea 80139

1,2-dinitroglycerol + NADPH = 1-nitroglycerol + nitrite + NADP(+)

Direction not assertedBalancedRhea 80143

1,3-dinitroglycerol + NADPH = 1-nitroglycerol + nitrite + NADP(+)

Direction not assertedBalancedRhea 80147

cyclohex-2-enone + NADPH + H(+) = cyclohexanone + NADP(+)

Direction not assertedBalancedRhea 80151

nitroglycerin + NADH = 1,3-dinitroglycerol + nitrite + NAD(+)

Left to rightBalancedRhea 80155

nitroglycerin + NADH = 1,2-dinitroglycerol + nitrite + NAD(+)

Left to rightBalancedRhea 80159

pentaerythritol tetranitrate + NADPH = pentaerythritol trinitrate + nitrite + NADP(+)

Direction not assertedBalancedRhea 80163

pentaerythritol trinitrate + NADPH = pentaerythritol dinitrate + nitrite + NADP(+)

Direction not assertedBalancedRhea 80167

2,4,6-trinitrotoluene + NADPH = 4-methyl-1,3,5-trinitrocyclohexa-2,4-dien-1-ide + NADP(+)

Direction not assertedBalancedRhea 80171

4-methyl-1,3,5-trinitrocyclohexa-2,4-dien-1-ide + NADPH + H(+) = 2-methyl-1,3,5-trinitrocyclohex-2-en-1-ide + NADP(+)

Direction not assertedBalancedRhea 80175

mogrol + UDP-alpha-D-glucose = mogroside I-A1 + UDP + H(+)

Direction not assertedBalancedRhea 80179

mogroside I-A1 + UDP-alpha-D-glucose = mogroside IIE + UDP + H(+)

Direction not assertedBalancedRhea 80183

mogroside IIE + UDP-alpha-D-glucose = mogroside IIIX + UDP + H(+)

Direction not assertedBalancedRhea 80187

2,4-dinitrotoluene + 2 NADPH + 2 H(+) = 4-hydroxylamino-2-nitrotoluene + 2 NADP(+) + H2O

Direction not assertedBalancedRhea 80191

4-nitrobenzoate + 2 NADPH + 2 H(+) = 4-hydroxylaminobenzoate + 2 NADP(+) + H2O

Direction not assertedBalancedRhea 80195

4-nitrobenzoate + 2 NADH + 2 H(+) = 4-hydroxylaminobenzoate + 2 NAD(+) + H2O

Direction not assertedBalancedRhea 80199

4-hydroxylaminobenzoate + H2O + H(+) = 3,4-dihydroxybenzoate + NH4(+)

Direction not assertedBalancedRhea 80203

cyclo(L-arginyl-tyrosyl) + reduced [NADPH--hemoprotein reductase] + O2 = cyclo(L-arginyl-L-dehydrotyrosyl) + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 80207

cyclo(L-arginyl-L-dehydrotyrosyl) + AH2 + O2 = cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) + A + H2O

Direction not assertedBalancedRhea 80211

(S)-2,3-epoxysqualene = motiol

Direction not assertedBalancedRhea 80215

motiol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 4beta-carboxyl motiol + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 80219

4beta-carboxyl motiol + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha-hydroxyl, 4beta-carboxyl motiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 80223

2alpha-hydroxyl, 4beta-carboxyl motiol + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = polytolypin + 4 oxidized [NADPH--hemoprotein reductase] + 5 H2O + 5 H(+)

Direction not assertedBalance undeterminableRhea 80227

4beta-carboxyl motiol + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = 2-deoxypolytolypin + 4 oxidized [NADPH--hemoprotein reductase] + 5 H2O + 5 H(+)

Direction not assertedBalance undeterminableRhea 80231

2-deoxypolytolypin + reduced [NADPH--hemoprotein reductase] + O2 = polytolypin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 80235

1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-ethanolamine = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Direction not assertedBalancedRhea 80239

1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Direction not assertedBalancedRhea 80243

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-ethanolamine = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)

Direction not assertedBalancedRhea 80247

cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) + O-acetyl-L-homoserine = cyclo(L-arginyl-(Z)-dehydro-4-O-homoseryl-tyrosyl) + acetate + H(+)

Direction not assertedBalancedRhea 80251

cyclo(L-arginyl-(Z)-dehydro-4-O-homoseryl-tyrosyl) + citrate + ATP = NK13650 B + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 80255

NK13650 B + S-adenosyl-L-methionine = NK13650 D + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 80259

NK13650 D + L-aspartate + ATP = NK13650 C + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 80263

NK13650 B + L-aspartate + ATP = NK13650 A + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 80267

(S)-lactate + ATP + H(+) = (S)-lactoyl-AMP + diphosphate

Left to rightBalancedRhea 80271

(S)-lactoyl-AMP + L-lysyl-[protein] = N(6)-[(S)-lactoyl]-L-lysyl-[protein] + AMP + 2 H(+)

Left to rightBalance undeterminableRhea 80275

tirucalla-7,24-dien-3beta-ol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = dihydroniloticin + 2 oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 80279

dihydroniloticin + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = melianol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 80283

N(6)-[(S)-lactoyl]-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-(S)-lactoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 80287

melianol + reduced [NADPH--hemoprotein reductase] + O2 = 7,8-epoxymelianol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 80291

7,8-epoxymelianol = isomeliandiol

Direction not assertedBalancedRhea 80295

Page 597 of 629