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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

28,901–28,950 of 31,435, by identifier

D-glutamate + acetyl-CoA = N-acetyl-D-glutamate + CoA + H(+)
Direction not assertedBalancedRhea 76495
N-acetyl-D-glutamate = N-acetyl-L-glutamate
Direction not assertedBalancedRhea 76499
4-O-beta-D-glucosyl-trans-ferulate + H2O = 4-O-beta-D-glucosyl-vanillin + acetate
Direction not assertedBalancedRhea 76503
(-)-2'-epi-GR24 + H2O = (-)-2'-epi-GR24 ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one
Direction not assertedBalancedRhea 76507
5-deoxystrigol + H2O = 5-deoxystrigol ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one
Direction not assertedBalancedRhea 76511
orobanchol + H2O = orobanchol ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one
Direction not assertedBalancedRhea 76515
N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + H2O = L-lysyl-[lipoyl-carrier protein] + (R)-lipoate

Direction not assertedBalance undeterminableRhea 76519

2-dehydro-3-deoxy-L-fuconate = (S)-lactaldehyde + pyruvate

Direction not assertedBalancedRhea 76523

2'-deoxyguanosine + H2O + H(+) = 2'-deoxyxanthosine + NH4(+)

Direction not assertedBalancedRhea 76527

N-acetyl-S-(2-succino)-L-cysteine + NADH + O2 + H(+) = N-acetyl-L-cysteine + oxaloacetate + NAD(+) + H2O

Direction not assertedBalancedRhea 76531

FAD(in) = FAD(out)

Direction not assertedBalancedTransportRhea 76535

sphinga-(4E,8E)-dienine + a fatty acyl-CoA = an N-acyl-sphinga-4,8-dienine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 76539

N-acetyl-S-(2-succino)-L-cysteine = N-acetyl-L-cysteine + fumarate

Direction not assertedBalancedRhea 76543

D-glutamine + acetyl-CoA = N-acetyl-D-glutamine + CoA + H(+)

Direction not assertedBalancedRhea 76547

D-aspartate + acetyl-CoA = N-acetyl-D-aspartate + CoA + H(+)

Direction not assertedBalancedRhea 76551

L-aspartyl-tRNA(Asp) + ergosterol = 1-(ergostan-3beta-yl)-L-aspartate + tRNA(Asp)

Direction not assertedBalancedRhea 76555

1-(ergostan-3beta-yl)-L-aspartate + H2O = ergosterol + L-aspartate + H(+)

Direction not assertedBalancedRhea 76559

an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 76563

3'-dehydrocarminate + H(+) = kermesate + 1,5-anhydro-D-erythro-hex-1-en-3-ulose

Direction not assertedBalancedRhea 76567

4-deoxy-L-erythro-hex-4-enopyranuronate = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate

Direction not assertedBalancedRhea 76571

4-deoxy-L-threo-hex-4-enopyranuronate = 5-dehydro-4-deoxy-D-glucuronate

Direction not assertedBalancedRhea 76575

(2S)-5,5-dimethyl-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADPH + 2 H(+) = (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + NADP(+)

Direction not assertedBalancedRhea 76579

(2S)-5,5-dimethyl-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADH + 2 H(+) = (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + NAD(+)

Direction not assertedBalancedRhea 76583

(6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + 2-oxoglutarate + AH2 + O2 + H(+) = (2S)-5,5-dimethylpiperidine-2-carboxylate + succinate + A + 2 CO2 + H2O

Direction not assertedBalancedRhea 76587

N,N-dimethylglycine(out) + Na(+)(out) = N,N-dimethylglycine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 76591

a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)

Direction not assertedBalance undeterminableTransportRhea 76595

(9Z,12Z)-octadecadienoate + H2O = (12Z)-10-hydroxyoctadecenoate

Direction not assertedBalancedRhea 76599

(12Z)-10-hydroxyoctadecenoate + H2O = 10,13-dihydroxyoctadecanoate

Direction not assertedBalancedRhea 76603

(9Z,12Z,15Z)-octadecatrienoate + H2O = (12Z,15Z)-10-hydroxyoctadecadienoate

Direction not assertedBalancedRhea 76607

vanillin + NADPH + H(+) = 4-hydroxy-3-methoxy-benzenemethanol + NADP(+)

Direction not assertedBalancedRhea 76611

3-oxopropanoate + NAD(+) + CoA + H2O = hydrogencarbonate + acetyl-CoA + NADH + H(+)

Left to rightBalancedRhea 76615

(6E)-8-methylnon-6-enoyl-CoA + 4-hydroxy-3-methoxy-benzenemethanol = capsiate + CoA

Direction not assertedBalancedRhea 76619

(R)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)

Left to rightBalancedRhea 76623

(S)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)

Left to rightBalancedRhea 76627

Ca(2+)(in) + n H(+)(out) = Ca(2+)(out) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 76631

Mn(2+)(in) + n H(+)(out) = Mn(2+)(out) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 76635

cytosine(out) = cytosine(in)

Direction not assertedBalancedTransportRhea 76639

xanthine(out) = xanthine(in)

Direction not assertedBalancedTransportRhea 76643

(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O

Direction not assertedBalancedRhea 76647

3-methylbutanal + NADP(+) + H2O = 3-methylbutanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76651

3-methylbutanal + NAD(+) + H2O = 3-methylbutanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 76655

butanal + NADP(+) + H2O = butanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76659

pentanal + NADP(+) + H2O = pentanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76663

furfural + NAD(+) + H2O = 2-furoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 76667

furfural + NADP(+) + H2O = 2-furoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76671

1-deoxysphinganine + a fatty acyl-CoA = N-acyl-1-deoxysphinganine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 76675

sulfoacetaldehyde + NAD(+) + CoA = sulfoacetyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 76679

sulfoacetate + ATP + CoA = sulfoacetyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 76683

(9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione = (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76687

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76691

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