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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

28,201–28,250 of 31,435, by identifier

3'-AMP(in) + ADP(out) + H(+)(out) = 3'-AMP(out) + ADP(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 73679
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acylsphing-4-enine = an N-acylsphing-4-enine-(1D-myo-inositol) + a 1,2-diacyl-sn-glycerol
Direction not assertedBalance undeterminableRhea 73683
dAMP(out) + phosphate(in) = dAMP(in) + phosphate(out)
Direction not assertedBalancedTransportRhea 73687
3'-AMP(out) + phosphate(in) = 3'-AMP(in) + phosphate(out)
Direction not assertedBalancedTransportRhea 73691
dADP(out) + phosphate(in) + H(+)(out) = dADP(in) + phosphate(out) + H(+)(in)
Direction not assertedBalancedTransportRhea 73695
dATP(out) + ADP(in) = dATP(in) + ADP(out)
ReversibleBalancedTransportRhea 73699

UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-glucuronate(out) = UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-glucuronate(in)

Left to rightBalancedTransportRhea 73703

UDP(out) + ATP(in) = UDP(in) + ATP(out)

Left to rightBalancedTransportRhea 73707

UTP(out) + ATP(in) = UTP(in) + ATP(out)

Left to rightBalancedTransportRhea 73711

dATP(out) + ATP(in) = dATP(in) + ATP(out)

Left to rightBalancedTransportRhea 73715

3,4-dihydroxybenzoate + S-adenosyl-L-methionine = vanillate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 73719

(S)-benzodiazepinedione + dimethylallyl diphosphate = (2R,3S,11S)-aszonalenin + diphosphate

Direction not assertedBalancedRhea 73723

(R)-benzodiazepinedione + dimethylallyl diphosphate = (2S,3R,11R)-aszonalenin + diphosphate

Direction not assertedBalancedRhea 73727

(S)-benzodiazepinedione + dimethylallyl diphosphate = (2S,3R,11S)-aszonalenin + diphosphate

Direction not assertedBalancedRhea 73731

trans-resveratrol + O2 = 3,5-dihydroxybenzaldehyde + 4-hydroxybenzaldehyde

Direction not assertedBalancedRhea 73735

dopamine(in) + 2 H(+)(out) = dopamine(out) + 2 H(+)(in)

Left to rightBalancedTransportRhea 73739

serotonin(in) + 2 H(+)(out) = serotonin(out) + 2 H(+)(in)

Left to rightBalancedTransportRhea 73743

(R)-noradrenaline(in) + 2 H(+)(out) = (R)-noradrenaline(out) + 2 H(+)(in)

Left to rightBalancedTransportRhea 73747

(R)-adrenaline(in) + 2 H(+)(out) = (R)-adrenaline(out) + 2 H(+)(in)

Direction not assertedBalancedTransportRhea 73751

histamine(in) + 2 H(+)(out) = histamine(out) + 2 H(+)(in)

Left to rightBalancedTransportRhea 73755

guanosine(2553) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2553) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 73759

L-tryptophan + L-alanine + 2 ATP = cyclo(L-tryptophyl-L-alanyl) + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 73763

cyclo(L-tryptophyl-L-alanyl) + dimethylallyl diphosphate = preechinulin + diphosphate

Direction not assertedBalancedRhea 73767

preechinulin + reduced [NADPH--hemoprotein reductase] + O2 = neoechinulin A + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 73771

preechinulin + dimethylallyl diphosphate = tardioxopiperazine B + diphosphate

Direction not assertedBalancedRhea 73775

preechinulin + dimethylallyl diphosphate = tardioxopiperazine A + diphosphate

Direction not assertedBalancedRhea 73779

tardioxopiperazine A + dimethylallyl diphosphate = echinulin + diphosphate

Direction not assertedBalancedRhea 73783

tardioxopiperazine A + dimethylallyl diphosphate = variecolorin L + diphosphate

Direction not assertedBalancedRhea 73787

neoechinulin A + dimethylallyl diphosphate = variecolorin G + diphosphate

Direction not assertedBalancedRhea 73791

neoechinulin A + dimethylallyl diphosphate = isoechinulin A + diphosphate

Direction not assertedBalancedRhea 73795

isoechinulin A + dimethylallyl diphosphate = dehydroechinulin + diphosphate

Direction not assertedBalancedRhea 73799

neoechinulin B + dimethylallyl diphosphate = isoechinulin B + diphosphate

Direction not assertedBalancedRhea 73803

GDP + S-adenosyl-L-methionine = N(7)-methyl-GDP + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 73807

L-proline(in) = L-proline(out)

Direction not assertedBalancedTransportRhea 73811

piceatannol + O2 = 3,5-dihydroxybenzaldehyde + 3,4-dihydroxybenzaldehyde

Direction not assertedBalancedRhea 73815

choline(in) + 2 H(+)(out) = choline(out) + 2 H(+)(in)

Left to rightBalancedTransportRhea 73819

an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)

Direction not assertedBalance undeterminableRhea 73823

an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)

Direction not assertedBalance undeterminableRhea 73827

an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)

Direction not assertedBalance undeterminableRhea 73831

sn-3-(O-farnesylgeranyl)glycerol 1-phosphate + (2E,6E,10E,14E)-geranylfarnesyl diphosphate = 2,3-bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + diphosphate

Direction not assertedBalancedRhea 73835

phenol + ATP + H2O = phenyl phosphate + AMP + phosphate + 2 H(+)

Direction not assertedBalancedRhea 73839

a 27-hydroxysterol + UDP-alpha-D-glucose = a sterol 27-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 73843

17alpha-hydroxywithaferin A + UDP-alpha-D-glucose = 17alpha-sitoindoside IX + UDP + H(+)

Direction not assertedBalancedRhea 73847

27-hydroxywithanone + UDP-alpha-D-glucose = withanone 27-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 73851

5alpha,6beta,17alpha,27-tetrahydroxywithanolide + UDP-alpha-D-glucose = 5alpha,6beta,17alpha-trihydroxywithanolide 27-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 73855

1-methylnicotinamide(out) = 1-methylnicotinamide(in)

Direction not assertedBalancedTransportRhea 73859

dopamine(out) = dopamine(in)

Direction not assertedBalancedTransportRhea 73863

serotonin(out) = serotonin(in)

Direction not assertedBalancedTransportRhea 73867

(R)-noradrenaline(out) = (R)-noradrenaline(in)

Direction not assertedBalancedTransportRhea 73871

(R)-adrenaline(out) = (R)-adrenaline(in)

Direction not assertedBalancedTransportRhea 73875

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