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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,351–27,400 of 31,435, by identifier

1D-myo-inositol 1,3,4-trisphosphate + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = 1D-myo-inositol 3,4,5,6-tetrakisphosphate + 1D-myo-inositol 1,3,4,6-tetrakisphosphate
ReversibleBalancedRhea 70263
hydrogencarbonate(in) + Na(+)(in) = hydrogencarbonate(out) + Na(+)(out)
Direction not assertedBalancedTransportRhea 70267
1D-myo-inositol 1,3,4-trisphosphate + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = 1D-myo-inositol 3,4,5,6-tetrakisphosphate + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
ReversibleBalancedRhea 70271
raffinose + H2O = sucrose + D-galactose
Direction not assertedBalancedRhea 70275
stachyose + H2O = raffinose + D-galactose
Direction not assertedBalancedRhea 70279
N-acetylputrescine + O2 + H2O = 4-acetamidobutanal + H2O2 + NH4(+)
Left to rightBalancedRhea 70283
1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+)

ReversibleBalancedRhea 70287

3-(2-aminophenyl)-3-oxopropanal = quinolin-4-ol + H2O

Direction not assertedBalancedRhea 70291

3-sulfino-L-alanine + 2-oxoglutarate = 3-sulfinopyruvate + L-glutamate

Right to leftBalancedRhea 70295

L-dehydroascorbate + H2O = 2,3-dioxo-L-gulonate

Direction not assertedBalancedRhea 70299

beta-D-glucosyl-N-octanoylsphing-4E-enine + cholesterol = N-octanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside

ReversibleBalancedRhea 70303

beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = N-dodecanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside

ReversibleBalancedRhea 70307

beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine

ReversibleBalancedRhea 70311

beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol = N-(15Z-tetracosenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside

ReversibleBalancedRhea 70315

1D-myo-inositol 1,3,4-trisphosphate + H2O = 1D-myo-inositol 3,4-bisphosphate + phosphate

Left to rightBalancedRhea 70319

2,3-dioxo-L-gulonate = 2-carboxy-L-lyxonolactone

Direction not assertedBalancedRhea 70323

(2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NAD(+) = 4-methylsulfanyl-2-oxobutanoate + NADH + H(+)

Direction not assertedBalancedRhea 70327

3-hydroxyphenylacetyl-CoA + H2O = 3-hydroxyphenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70331

2-carboxy-L-lyxonolactone + H2O = 2-carboxy-L-lyxonate + H(+)

Direction not assertedBalancedRhea 70335

alpha-D-Gal-(1->6)-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + H2O = beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + D-galactose

Direction not assertedBalancedRhea 70339

L-tyrosine + chloride + NADP(+) = 3-chloro-L-tyrosine + NADPH

Right to leftBalancedRhea 70343

bromide + L-tyrosine + NADP(+) = 3-bromo-L-tyrosine + NADPH

Right to leftBalancedRhea 70347

beta-D-Man-(1->4)-[alpha-D-Gal-(1->6)]-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + H2O = beta-D-Man-(1->4)-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + D-galactose

Direction not assertedBalancedRhea 70351

1-carboxybiuret + H(+) = biuret + CO2

Direction not assertedBalancedRhea 70355

3-oxosphinganine + a fatty acyl-CoA = N-acyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 70359

cyanurate + H2O = 1-carboxybiuret + H(+)

Direction not assertedBalancedRhea 70363

3-oxosphinganine + octanoyl-CoA = N-octanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70367

3-oxosphinganine + decanoyl-CoA = N-decanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70371

3-oxosphinganine + dodecanoyl-CoA = N-dodecanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70375

3-oxosphinganine + tetradecanoyl-CoA = N-tetradecanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70379

3-oxosphinganine + hexadecanoyl-CoA = N-hexadecanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70383

3-oxosphinganine + octadecanoyl-CoA = N-octadecanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70387

3-oxosphinganine + eicosanoyl-CoA = N-eicosanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70391

3-oxosphinganine + docosanoyl-CoA = N-docosanoyl-3-ketodihydrosphingosine + CoA + H(+)

Direction not assertedBalancedRhea 70395

3-oxosphinganine + tetracosanoyl-CoA = N-tetracosanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70399

3-oxosphinganine + (9Z)-hexadecenoyl-CoA = N-(9Z-hexadecenoyl)-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70403

[(2E,6E,10E)-geranylgeranyl]-L-cysteine + O2 + H2O = (2E,6E,10E)-geranylgeranial + L-cysteine + H2O2

Left to rightBalancedRhea 70407

4-hydroxyphenylacetyl-CoA + H2O = 4-hydroxyphenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70411

(3,5-dihydroxyphenyl)acetyl-CoA + H2O = (3,5-dihydroxyphenyl)acetate + CoA + H(+)

Direction not assertedBalancedRhea 70415

3,4-dihydroxyphenylacetyl-CoA + H2O = 3,4-dihydroxyphenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70419

an acyl-CoA + H2O = a carboxylate + CoA + H(+)

Direction not assertedBalance undeterminableRhea 70423

phenylacetyl-CoA + H2O = 2-phenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70427

Li(+)(in) + 2 H(+)(out) = Li(+)(out) + 2 H(+)(in)

Direction not assertedBalancedTransportRhea 70431

an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70435

an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70439

an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70443

an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70447

an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + succinate + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 70451

sarcosine + (6S)-5,6,7,8-tetrahydrofolate + O2 = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2

Direction not assertedBalancedRhea 70455

a 1,N(6)-etheno-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyadenosine in single-stranded DNA + glyoxal + succinate + CO2

Left to rightBalance undeterminableRhea 70459

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