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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,251–27,300 of 31,435, by identifier

a uridine in 12S rRNA + S-adenosyl-L-methionine = a 5-methyluridine in 12S rRNA + S-adenosyl-L-homocysteine + H(+)
Left to rightBalance undeterminableRhea 69859
a uridine in mRNA + S-adenosyl-L-methionine = a 5-methyluridine in mRNA + S-adenosyl-L-homocysteine + H(+)
Left to rightBalance undeterminableRhea 69863
a uridine in RNA + S-adenosyl-L-methionine = a 5-methyluridine in RNA + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalance undeterminableRhea 69867
cholestanol + reduced [NADPH--hemoprotein reductase] + O2 = (22S)-22-hydroxycholestanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 69871
6-deoxocastasterone + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxycastasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 69875
6alpha-hydroxycastasterone + reduced [NADPH--hemoprotein reductase] + O2 = castasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

? Direction not asserted

Balance undeterminable

Rhea 69879

L-ascorbate(out) + 2 Na(+)(out) = L-ascorbate(in) + 2 Na(+)(in)

Left to rightBalancedTransportRhea 69883

uridine(out) + Na(+)(out) = uridine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 69887

thymidine(out) + Na(+)(out) = thymidine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 69891

cytidine(out) + Na(+)(out) = cytidine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 69895

thymidine(out) + 2 Na(+)(out) = thymidine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 69899

cytidine(out) + 2 Na(+)(out) = cytidine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 69903

uridine(out) + 2 Na(+)(out) = uridine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 69907

adenosine(out) + 2 Na(+)(out) = adenosine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 69911

guanosine(out) + 2 Na(+)(out) = guanosine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 69915

inosine(out) + 2 Na(+)(out) = inosine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 69919

castasterone + reduced [NADPH--hemoprotein reductase] + O2 = brassinolide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 69923

adenosine(out) + Na(+)(out) = adenosine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 69927

inosine(out) + Na(+)(out) = inosine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 69931

guanosine(out) + Na(+)(out) = guanosine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 69935

6-deoxotyphasterol + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxytyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 69939

6alpha-hydroxytyphasterol + reduced [NADPH--hemoprotein reductase] + O2 = typhasterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69943

3-dehydro-6-deoxoteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydro-6alpha-hydroxyteasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 69947

3-dehydro-6alpha-hydroxyteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydroteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69951

Ca(2+)(in) + 3 Na(+)(out) = Ca(2+)(out) + 3 Na(+)(in)

Direction not assertedBalancedTransportRhea 69955

6-deoxoteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxyteasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 69959

6alpha-hydroxytyphasterol + reduced [NADPH--hemoprotein reductase] + O2 = teasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69963

Ca(2+)(out) + K(+)(out) + 4 Na(+)(in) = Ca(2+)(in) + K(+)(in) + 4 Na(+)(out)

Direction not assertedBalancedTransportRhea 69967

(22S)-22-hydroxycampesterol + reduced [NADPH--hemoprotein reductase] + O2 = (22S)-22-hydroxycampest-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69971

6-deoxycathasterone + reduced [NADPH--hemoprotein reductase] + O2 = (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69975

(22R,23R)-22,23-dihydroxycampesterol + reduced [NADPH--hemoprotein reductase] + O2 = (22R,23R)-22,23-dihydroxycampest-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69979

6-deoxoteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydro-6-deoxoteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 69983

(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP(+) = (22S)-22-hydroxycampest-4-en-3-one + NADPH + H(+)

Direction not assertedBalancedRhea 69987

3-dehydro-6-deoxoteasterone + NADP(+) = (22R,23R)-22,23-dihydroxycampest-4-en-3-one + NADPH + H(+)

Direction not assertedBalancedRhea 69991

L-threonine(in) + Na(+)(in) = L-threonine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 69999

6-oxocampestanol + reduced [NADPH--hemoprotein reductase] + O2 = cathasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 70003

anthranilate + ATP + H(+) = 2-aminobenzoyl-AMP + diphosphate

Direction not assertedBalancedRhea 70007

2-aminobenzoyl-AMP + CoA = anthraniloyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 70011

teasterone + reduced [NADPH--hemoprotein reductase] + O2 = 7-oxateasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 70015

typhasterol + reduced [NADPH--hemoprotein reductase] + O2 = 7-oxatyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 70019

4-hydroxy-L-proline(in) + Na(+)(in) = 4-hydroxy-L-proline(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 70023

N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine = N(6)-methyl,N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70027

6-deoxocastasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = castasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 70031

6-deoxotyphasterol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = typhasterol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 70035

3-dehydro-6-deoxoteasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 3-dehydroteasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 70039

6-deoxoteasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = teasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 70043

2-oxoadipate + L-kynurenine = L-2-aminoadipate + kynurenate + H2O

Left to rightBalancedRhea 70047

2-oxoadipate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminoadipate

Direction not assertedBalancedRhea 70051

cremeomycin + AH2 = 2-hydroxy-4-methoxybenzoate + N2 + A

Direction not assertedBalancedRhea 70055

a C27-steroid + reduced [NADPH--hemoprotein reductase] + O2 = a (22S)-22-hydroxy C27-steroid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 70059

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