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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,051–27,100 of 31,435, by identifier

N(omega)-methyl-L-arginine + NADH + O2 + H(+) = N(delta)-hydroxy-N(omega)-methyl-L-arginine + NAD(+) + H2O
Direction not assertedBalancedRhea 69056
N(delta)-hydroxy-N(omega)-methyl-L-arginine + NADH + O2 = N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + NAD(+) + H2O
Direction not assertedBalancedRhea 69060
N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + O2 = N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + H2O
Direction not assertedBalancedRhea 69064
2 N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + AH2 = 2 N(delta)-hydroxy-N(omega)-methyl-L-citrulline + 2 nitric oxide + A
Direction not assertedBalancedRhea 69068
serotonin + O2 + H2O = (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+)
Direction not assertedBalancedRhea 69072
(R)-noradrenaline + O2 + H2O = (R)-3,4-dihydroxymandelaldehyde + H2O2 + NH4(+)
Direction not asserted

Balanced

Rhea 69076

3,4-dihydroxyphenylacetaldehyde + NAD(+) + H2O = 3,4-dihydroxyphenylacetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69080

acrolein + NAD(+) + H2O = acrylate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69084

butanal + NAD(+) + H2O = butanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69088

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69092

4-methylsulfanyl-2-oxobutanoate + L-kynurenine = kynurenate + L-methionine + H2O

Left to rightBalancedRhea 69096

4-methylsulfanyl-2-oxobutanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine

Direction not assertedBalancedRhea 69100

2-oxo-3-sulfanylpropanoate + L-kynurenine = kynurenate + L-cysteine + H2O

Left to rightBalancedRhea 69104

2-oxo-3-sulfanylpropanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine

Direction not assertedBalancedRhea 69108

L-2-aminoadipate + glyoxylate = 2-oxoadipate + glycine

Left to rightBalancedRhea 69112

L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine

Direction not assertedBalancedRhea 69116

glyoxylate + L-phenylalanine = 3-phenylpyruvate + glycine

Direction not assertedBalancedRhea 69120

L-tryptophan + glyoxylate = indole-3-pyruvate + glycine

Direction not assertedBalancedRhea 69124

L-leucine + glyoxylate = 4-methyl-2-oxopentanoate + glycine

Direction not assertedBalancedRhea 69128

cadaverine + O2 + H2O = 5-aminopentanal + H2O2 + NH4(+)

Left to rightBalancedRhea 69132

spermine + 2 O2 + 2 H2O = spermine dialdehyde + 2 H2O2 + 2 NH4(+)

Direction not assertedBalancedRhea 69136

N-(4-aminobutyl)-3-aminopropanal = acrolein + putrescine

Direction not assertedBalancedRhea 69140

agmatine + O2 + H2O = 4-guanidinobutanal + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69144

spermine + O2 + H2O = spermine monoaldehyde + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69148

spermine monoaldehyde = acrolein + spermidine

Direction not assertedBalancedRhea 69152

spermine dialdehyde = N-(4-aminobutyl)-3-aminopropanal + acrolein

Direction not assertedBalancedRhea 69156

agmatine + O2 + H2O = N-amidino-(2R)-hydroxypyrrolidine + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69160

N-(4-aminobutyl)-3-aminopropanal + NAD(+) + H2O = N-(2-carboxyethyl)putrescine + NADH + 2 H(+)

Direction not assertedBalancedRhea 69164

spermine monoaldehyde + NAD(+) + H2O = N-(2-carboxyethyl)spermidine + NADH + 2 H(+)

Direction not assertedBalancedRhea 69168

N(6)-(2E)-butenoyl-L-lysyl-[protein] + H2O = (2E)-2-butenoate + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 69172

N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + H2O = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 69176

thiamine diphosphate + ADP = thiamine triphosphate + AMP

Direction not assertedBalancedRhea 69180

sn-glycerol 1-phosphate + (2E,6E,10E,14E)-geranylfarnesyl diphosphate = sn-3-(O-farnesylgeranyl)glycerol 1-phosphate + diphosphate

Direction not assertedBalancedRhea 69184

gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate + ATP = L-glutamyl-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69188

L-glutamyl-[tubulin] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69192

L-glutamyl-[beta-tubulin] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69196

gamma-L-glutamyl-L-glutamyl-[tubulin] + L-glutamate + ATP = L-glutamyl-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69200

gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate + ATP = L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69204

(L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + L-glutamate + ATP = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69208

(L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate + ATP = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69212

(omega-1)-methyl-(3R)-hydroxy-fatty acyl-CoA + NADP(+) = (omega-1)-methyl-3-oxo-fatty acyl-CoA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 69216

a (Z)-glucosinolate + H2O = a (Z)-N-(sulfonatooxy)alkanimidothioate + D-glucose + H(+)

Direction not assertedBalance undeterminableRhea 69220

a (Z)-alkenyl glucosinolate + H2O = a (Z)-N-(sulfonatooxy)alkenimidothioate + D-glucose + H(+)

Direction not assertedBalance undeterminableRhea 69224

a (Z)-N-(sulfonatooxy)alkenimidothioate = an epithionitrile + sulfate

Direction not assertedBalance undeterminableRhea 69228

(Z)-3-hydroxypropyl glucosinolate + H2O = (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69232

(Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate = 4-hydroxybutylnitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69236

glucoraphanin + H2O = (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69240

(Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate = 5-methylsulfinylpentyl nitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69244

sinigrin + H2O = (Z)-N-(sulfonatooxy)prop-2-enimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69248

(Z)-N-(sulfonatooxy)prop-2-enimidothioate = 2-(thiiran-2-yl)acetonitrile + sulfate

Direction not assertedBalancedRhea 69252

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