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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

26,801–26,850 of 31,435, by identifier

a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + H(+)
Left to rightBalance undeterminableRhea 68056
a 14alpha-methyl steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 14alpha-hydroxymethyl steroid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 68060
a 14alpha-hydroxymethyl steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 14alpha-formyl steroid + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Left to rightBalance undeterminableRhea 68064
a 14alpha-formyl steroid + reduced [NADPH--hemoprotein reductase] + O2 = a Delta(14) steroid + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Left to rightBalance undeterminableRhea 68068
Delta(2)-thiazoline-2-carboxylate + NADPH + 2 H(+) = L-thiazolidine-2-carboxylate + NADP(+)
Left to rightBalancedRhea 68072
a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate

→ Left to right

Balance undeterminable

Rhea 68076

a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate + H(+)

Left to rightBalance undeterminableRhea 68080

L-histidyl-[RNA ligase] + GTP = N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] + diphosphate

Left to rightBalance undeterminableRhea 68084

N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] + a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) = a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase]

Left to rightBalance undeterminableRhea 68088

a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + a 5'-end dephospho-ribonucleoside-RNA = a ribonucleotidyl-ribonucleotide-RNA + GMP + H(+)

Left to rightBalance undeterminableRhea 68092

a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end ribonucleotide-RNA + a 5'-end 5'-phospho-ribonucleoside-RNA + H(+)

Left to rightBalance undeterminableRhea 68096

xylitol + NAD(+) = L-xylulose + NADH + H(+)

Direction not assertedBalancedRhea 68100

all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone

Left to rightBalancedRhea 68104

L-glucitol + NAD(+) = keto-L-fructose + NADH + H(+)

Direction not assertedBalancedRhea 68108

propanamide + H2O = propanoate + NH4(+)

Direction not assertedBalancedRhea 68112

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol = an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a triacylglycerol

Direction not assertedBalance undeterminableRhea 68116

a 1,2-diacylglycerol + a fatty acyl-CoA = a triacylglycerol + CoA

Direction not assertedBalance undeterminableRhea 68120

a fatty acyl-[ACP] + a 1,2-diacylglycerol = a triacylglycerol + holo-[ACP]

Direction not assertedBalance undeterminableRhea 68124

phytol + a fatty acyl-CoA = a fatty acid phytyl ester + CoA

Direction not assertedBalance undeterminableRhea 68128

phytol + tetradecanoyl-CoA = tetradecanoate phytyl ester + CoA

Direction not assertedBalancedRhea 68132

acetophenone + NADPH + H(+) = (R)-1-phenylethanol + NADP(+)

Direction not assertedBalancedRhea 68136

2,5-hexanedione + 2 NADPH + 2 H(+) = (2R,5R)-hexanediol + 2 NADP(+)

Direction not assertedBalancedRhea 68140

ethyl 3-oxobutanoate + NADPH + H(+) = ethyl (R)-3-hydroxybutanoate + NADP(+)

Direction not assertedBalancedRhea 68144

2-octanone + NADPH + H(+) = (2R)-octan-2-ol + NADP(+)

Direction not assertedBalancedRhea 68148

a 1,3-diacylglycerol + a fatty acyl-CoA = a triacylglycerol + CoA

Direction not assertedBalance undeterminableRhea 68152

(2E)-geranyl diphosphate + L-glutamate = N-geranyl-L-glutamate + diphosphate

Direction not assertedBalancedRhea 68156

N-geranyl-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2 = N-(8'-hydroxygeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68160

N-(8'-hydroxygeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2 = N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 68164

N-(8'-oxogeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2 = N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 68168

N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + 2-oxoglutarate + O2 = isodomoate A + succinate + CO2 + H2O

Direction not assertedBalancedRhea 68172

N-geranyl-L-glutamate + 2-oxoglutarate + O2 = dainate A + succinate + CO2 + H2O

Direction not assertedBalancedRhea 68176

a short-chain fatty acyl-CoA + H2O = a short-chain fatty acid + CoA + H(+)

Direction not assertedBalance undeterminableRhea 68180

a medium-chain fatty acyl-CoA + H2O = a medium-chain fatty acid + CoA + H(+)

Direction not assertedBalance undeterminableRhea 68184

phytol + dodecanoyl-CoA = dodecanoate phytyl ester + CoA

Direction not assertedBalancedRhea 68188

phytol + decanoyl-CoA = decanoate phytyl ester + CoA

Direction not assertedBalancedRhea 68192

1,2-dihexanoylglycerol + tetradecanoyl-CoA = 1,2-dihexanoyl-3-tetradecanoylglycerol + CoA

Direction not assertedBalancedRhea 68196

1,2-dihexanoylglycerol + hexadecanoyl-CoA = 1,2-dihexanoyl-3-hexadecanoylglycerol + CoA

Direction not assertedBalancedRhea 68200

1,2-dihexanoylglycerol + octadecanoyl-CoA = 1,2-dihexanoyl-3-octadecanoylglycerol + CoA

Direction not assertedBalancedRhea 68204

(7Z,10Z,13Z)-hexadecatrienoyl-CoA + 1,2-dihexanoylglycerol = 1,2-dihexanoyl-3-(7Z,10Z,13Z-hexadecatrienoyl)-glycerol + CoA

Direction not assertedBalancedRhea 68208

1,2-dihexanoylglycerol + (9Z)-octadecenoyl-CoA = 1,2-dihexanoyl-3-(9Z-octadecenoyl)-glycerol + CoA

Direction not assertedBalancedRhea 68212

1,2-dihexanoylglycerol + (9Z,12Z,15Z)-octadecatrienoyl-CoA = 1,2-dihexanoyl-3-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + CoA

Direction not assertedBalancedRhea 68216

(7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol = (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA

Direction not assertedBalancedRhea 68220

prekainate + 2-oxoglutarate + O2 + H(+) = kainate lactone + succinate + CO2 + H2O

Direction not assertedBalancedRhea 68224

glycine(in) + Na(+)(in) = glycine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68228

L-cysteine(in) + Na(+)(in) = L-cysteine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68232

L-glutamine(in) + Na(+)(in) = L-glutamine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68236

L-methionine(in) + Na(+)(in) = L-methionine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68240

L-phenylalanine(in) + Na(+)(in) = L-phenylalanine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68244

L-tyrosine(in) + Na(+)(in) = L-tyrosine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 68248

L-tryptophan(in) + Na(+)(in) = L-tryptophan(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 68252

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