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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Interactions
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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

26,551–26,600 of 31,435, by identifier

chermesin D + AH2 + O2 = asnovolin I + A + H2O
Direction not assertedBalancedRhea 67048
asnovolin J + AH2 + O2 = asnovolin A + A + H2O
Direction not assertedBalancedRhea 67052
chermesin D + S-adenosyl-L-methionine = chermesin D methyl ester + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 67056
asnovolin I + S-adenosyl-L-methionine = asnovolin K + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 67060
asnovolin K + AH2 = asnovolin A + A
Direction not assertedBalancedRhea 67064
chermesin D methyl ester + AH2 = asnovolin J + A
Direction not assertedBalancedRhea 67068
a very long-chain fatty acyl-CoA + H2O = a very long-chain fatty acid + CoA + H(+)

→ Left to right

Balance undeterminable

Rhea 67072

L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 67076

a very long-chain fatty acid(in) + ATP + H2O = a very long-chain fatty acid(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 67080

hexacosanoate(in) + ATP + H2O = hexacosanoate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 67084

tetracosanoate(in) + ATP + H2O = tetracosanoate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 67088

docosanoate(in) + ATP + H2O = docosanoate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 67092

asnovolin A + 2-oxoglutarate + 2 O2 = fumigatonoid A + succinate + CO2

Direction not assertedBalancedRhea 67096

fumigatonoid B = fumigatonoid C

Direction not assertedBalancedRhea 67100

fumigatonoid C + 2-oxoglutarate + O2 = novofumigatonin + succinate + CO2 + H2O

Direction not assertedBalancedRhea 67104

L-lysyl(37)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(37)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 67108

L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 67112

N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 67116

N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 67120

a hydroperoxide + L-cysteinyl-[protein] = S-hydroxy-L-cysteinyl-[protein] + an alcohol

Left to rightBalance undeterminableRhea 67124

L-pipecolate + malonyl-CoA + 3 NADPH + 5 H(+) = (1R,8aS)-octahydroindolizin-1-ol + CO2 + 3 NADP(+) + CoA + 2 H2O

Direction not assertedBalancedRhea 67128

L-pipecolate + malonyl-CoA + 3 NADPH + 5 H(+) = (1S,8aS)-octahydroindolizin-1-ol + CO2 + 3 NADP(+) + CoA + 2 H2O

Direction not assertedBalancedRhea 67132

3-hydroxypropanoate + ATP + CoA = 3-hydroxypropanoyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 67136

L-cysteinyl-[NO transferase protein] + N(omega)-hydroxy-L-arginine + O2 = S-nitroso-L-cysteinyl-[NO transferase protein] + L-citrulline + H2O + H(+)

Direction not assertedBalance undeterminableRhea 67140

jasmonate + 2-oxoglutarate + O2 = (1R,2R)-12-hydroxyjasmonate + succinate + CO2

Direction not assertedBalancedRhea 67144

L-cysteinyl-[NO transferase protein] + L-arginine + NADPH + 2 O2 = S-nitroso-L-cysteinyl-[NO transferase protein] + L-citrulline + NADP(+) + 2 H2O

Direction not assertedBalance undeterminableRhea 67148

S-nitroso-L-cysteinyl-[NO transferase protein] + L-cysteinyl-[protein] = L-cysteinyl-[NO transferase protein] + S-nitroso-L-cysteinyl-[protein]

Direction not assertedBalance undeterminableRhea 67152

1-O-(1Z-hexadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 67156

melleolide F + FADH2 + chloride + O2 = 6'-chloromelleolide F + FAD + 2 H2O + H(+)

Direction not assertedBalancedRhea 67160

melleolide F + bromide + FADH2 + O2 = 6'-bromomelleolide F + FAD + 2 H2O

Direction not assertedBalancedRhea 67164

3-hydroxy-L-phenylalanine + 2-oxoglutarate = 3-(3-hydroxyphenyl)pyruvate + L-glutamate

Direction not assertedBalancedRhea 67168

primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] + O2 = primary fluorescent dioxobilin-type chlorophyll catabolite + formate + oxidized [NADPH--hemoprotein reductase] + 2 H(+)

Direction not assertedBalance undeterminableRhea 67172

primary fluorescent dioxobilin-type chlorophyll catabolite + H2O = O13(4)-desmethyl pFDCC + methanol + H(+)

Direction not assertedBalancedRhea 67176

L-glutamyl-[protein] + glycine + ATP = glycyl-L-glutamyl-[protein] + ADP + phosphate + H(+)

Left to rightBalance undeterminableRhea 67180

(glycyl)(n)-glycyl-L-glutamyl-[protein] + glycine + ATP = (glycyl)(n+1)-glycyl-L-glutamyl-[protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 67184

an N-all-trans-retinylidenephosphatidylethanolamine(out) + ATP + H2O = an N-all-trans-retinylidenephosphatidylethanolamine(in) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 67188

N-11-cis-retinylidenephosphatidylethanolamine(out) + ATP + H2O = N-11-cis-retinylidenephosphatidylethanolamine(in) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 67192

N-acetylserotonin + H2O = serotonin + acetate

Direction not assertedBalancedRhea 67196

N-acetyltyramine + H2O = tyramine + acetate

Direction not assertedBalancedRhea 67200

N-acetyltryptamine + H2O = tryptamine + acetate

Direction not assertedBalancedRhea 67204

melatonin + H2O = 5-methoxytryptamine + acetate

Direction not assertedBalancedRhea 67208

(4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoyl-CoA + O2 = (2E,4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-2,4,8-trienoyl-CoA + H2O2

Direction not assertedBalancedRhea 67212

(4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-4,8-dimethyldeca-4,8-dienoyl-CoA = (2E,4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-2,4,8-trienoyl-CoA + H2O

Direction not assertedBalancedRhea 67216

(4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-4,8-dimethyldeca-4,8-dienoyl-CoA + NAD(+) = (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-4,8-dimethyldeca-4,8-dienoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 67220

(2E,6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-2,6-dimethylocta-2,6-dienoyl-CoA + acetyl-CoA = (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-4,8-dimethyldeca-4,8-dienoyl-CoA + CoA

Direction not assertedBalancedRhea 67224

(6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA = (2E,6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-2,6-dimethylocta-2,6-dienoyl-CoA + H2O

Direction not assertedBalancedRhea 67228

(6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA + NAD(+) = (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 67232

mycophenolyl-CoA + propanoyl-CoA = (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + CoA

Direction not assertedBalancedRhea 67236

(R)-S-adenosyl-L-methionine + H2O = adenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 67240

3-deoxyglucosone + NAD(+) + H2O = 2-dehydro-3-deoxy-D-gluconate + NADH + 2 H(+)

Left to rightBalancedRhea 67244

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