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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

25,601–25,650 of 31,435, by identifier

spectinomycin + ATP = 9-O-adenylylspectinomycin + diphosphate
Direction not assertedBalancedRhea 63228
(2E)-octenoyl-CoA + NADH + H(+) = octanoyl-CoA + NAD(+)
Direction not assertedBalancedRhea 63232
streptomycin + ATP = 6-O-adenylylstreptomycin + diphosphate
Direction not assertedBalancedRhea 63236
(-)-coronaridine + reduced [NADPH--hemoprotein reductase] + O2 = (-)-10-hydroxycoronaridine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 63240
(-)-ibogamine + reduced [NADPH--hemoprotein reductase] + O2 = noribogaine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 63244
(-)-10-hydroxycoronaridine + S-adenosyl-L-methionine = (-)-voacangine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 63248

noribogaine + S-adenosyl-L-methionine = (-)-ibogaine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 63252

1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 63256

5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H(+) = 4-pyridoxate + NAD(+)

Direction not assertedBalancedRhea 63260

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + O2 = 1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 63264

1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + O2 = 1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine

Left to rightBalancedRhea 63268

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 = 1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)

Left to rightBalancedRhea 63272

a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 = a 1-acyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)

Left to rightBalance undeterminableRhea 63276

a 1-acyl-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 = a 1-acyl-2-(15-hydroperoxy-8Z,11Z,13E-eicosatrienoyl)-sn-glycero-3-phospho-(1D-myo-inositol)

Left to rightBalance undeterminableRhea 63280

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 63284

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 9-hydroperoxy-(5Z,7E,11Z,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 63288

N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1248) in human 18S rRNA + S-methyl-5'-thioadenosine + H(+)

Left to rightBalance undeterminableRhea 63292

an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)

Left to rightBalance undeterminableRhea 63296

N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1191) in yeast 18S rRNA + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalance undeterminableRhea 63300

1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoate + H(+)

Left to rightBalancedRhea 63304

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 11-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 63308

(8Z,11Z,14Z)-eicosatrienoate + O2 = 15-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate

Left to rightBalancedRhea 63312

(9Z,12Z)-octadecadienoate + O2 = 9-hydroperoxy-(10E,12Z)-octadecadienoate

Direction not assertedBalancedRhea 63316

a glycerophospholipid(in) + ATP + H2O = a glycerophospholipid(out) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableTransportRhea 63320

1,2-dihexadecanoyl-sn-glycerol + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 63324

2-(9Z-octadecenoyl)-glycerol + ATP = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 63328

alpha-L-arabinopyanose = beta-L-arabinopyranose

Direction not assertedBalancedRhea 63332

alpha-D-xylose = beta-D-xylose

Direction not assertedBalancedRhea 63336

L-amino acyl-L-seryl-[protein] + ATP = (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 63340

L-amino acyl-L-threonyl-[protein] + ATP = (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 63344

L-amino acyl-L-cysteinyl-[protein] + ATP = (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 63348

octadecanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 63352

(1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 63356

(S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 63360

(S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-1,3-oxazole-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 63364

spermine(out) + ATP + H2O = spermine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 63368

L-cysteinyl-[protein] + an acyl-CoA = an S-acyl-L-cysteinyl-[protein] + CoA

Direction not assertedBalance undeterminableRhea 63372

an omega-methyl-ultra-long-chain fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an omega-hydroxy-ultra-long-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 63376

a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphocholine + H(+)

Left to rightBalance undeterminableRhea 63380

1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-2-acetyl-sn-glycerol + phosphocholine + H(+)

Left to rightBalancedRhea 63384

Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2

Left to rightBalancedRhea 63388

Fe(II)-heme o + A + H2O = Fe(II)-heme i + AH2

Direction not assertedBalancedRhea 63392

Fe(II)-heme i + A + H2O = Fe(II)-hydroxyheme i + AH2

Direction not assertedBalancedRhea 63396

Fe(II)-hydroxyheme i = Fe(II)-heme a + H2O

Direction not assertedBalancedRhea 63400

3,6-dichloropyridine-2,5-diol + FADH2 + O2 = 6-chloro-3-hydroxypyridine-2,5-dione + FAD + chloride + H2O + 2 H(+)

Direction not assertedBalancedRhea 63404

6-chloropyridine-2,3,5-triol + FADH2 + O2 = 3,6-dihydroxypyridine-2,5-dione + FAD + chloride + H2O + 3 H(+)

Direction not assertedBalancedRhea 63408

2,4,6-trichlorophenol + FADH2 + O2 = 2,6-dichlorobenzoquinone + FAD + chloride + H2O + H(+)

Direction not assertedBalancedRhea 63412

2,6-dichlorohydroquinone + FADH2 + O2 = 2-chloro-6-hydroxy-1,4-benzoquinone + FAD + chloride + H2O + 2 H(+)

Direction not assertedBalancedRhea 63416

2-hydroxyethylphosphonate + CTP = cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate

Direction not assertedBalancedRhea 63420

(2S)-2-phospholactate + GTP + H(+) = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate

Direction not assertedBalancedRhea 63424

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