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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

25,551–25,600 of 31,435, by identifier

(15Z)-tetracosenamide + H2O = (15Z)-tetracosenoate + NH4(+)
Left to rightBalancedRhea 63028
a fatty acylamide + H2O = a fatty acid + NH4(+)
Direction not assertedBalance undeterminableRhea 63032
octadecanamide + H2O = octadecanoate + NH4(+)
Direction not assertedBalancedRhea 63036
lovastatin + H2O = lovastatin carboxylate + H(+)
Direction not assertedBalancedRhea 63040
mevastatin + H2O = mevinic carboxylate + H(+)
Direction not assertedBalancedRhea 63044
pravastatin lactone + H2O = pravastatin + H(+)
Direction not assertedBalancedRhea 63048
1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O = methanol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

→ Left to right

Balanced

Rhea 63052

3 malonyl-CoA + acetyl-CoA + S-adenosyl-L-methionine + H(+) = 5-methylorsellinate + S-adenosyl-L-homocysteine + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 63056

5-methylorsellinate + ATP + NADPH + H(+) = 2,4-dihydroxy 5,6-dimethylbenzaldehyde + AMP + diphosphate + NADP(+)

Direction not assertedBalancedRhea 63060

3 malonyl-CoA + acetyl-CoA + 3 H(+) = tetraacetate lactone + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 63064

2 malonyl-CoA + acetyl-CoA + 2 H(+) = triacetate lactone + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 63068

3 malonyl-CoA + acetyl-CoA + 3 H(+) = orcinol + 4 CO2 + 4 CoA

Direction not assertedBalancedRhea 63072

3 malonyl-CoA + acetyl-CoA + 3 H(+) = 2-acetylphloroglucinol + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 63076

ilicicolinate B + AH2 + ATP = ilicicolin B + A + AMP + diphosphate

Direction not assertedBalancedRhea 63080

ilicicolin B + FADH2 + chloride + O2 = ilicicolin A + FAD + 2 H2O + H(+)

Direction not assertedBalancedRhea 63084

a ribonucleotide in U6 snRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in U6 snRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 63088

ilicicolin A + NADPH + O2 + H(+) = ilicicolin A epoxide + NADP(+) + H2O

Direction not assertedBalancedRhea 63092

ilicicolin A epoxide = ilicicolin C

Direction not assertedBalancedRhea 63096

ilicicolin C + NADPH + O2 + H(+) = ascochlorin + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 63100

ilicicolin A epoxide + NADPH + O2 + H(+) = 16-hydroxy-ilicicolin A epoxide + NADP(+) + H2O

Direction not assertedBalancedRhea 63104

16-hydroxy-ilicicolin A epoxide = ascofuranol

Direction not assertedBalancedRhea 63108

ascofuranol + A = ascofuranone + AH2

Direction not assertedBalancedRhea 63112

peroxynitrite = nitrate

Left to rightBalancedRhea 63116

(11Z)-eicosenamide + H2O = (11Z)-eicosenoate + NH4(+)

Left to rightBalancedRhea 63120

N-octadecanoyl ethanolamine + H2O = octadecanoate + ethanolamine

Left to rightBalancedRhea 63124

N-docosanoyl-ethanolamine + H2O = docosanoate + ethanolamine

Left to rightBalancedRhea 63128

apo-[alkylcobalamin reductase] + methylcob(III)alamin + glutathione = S-methyl glutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)

Left to rightBalance undeterminableRhea 63132

apo-[alkylcobalamin reductase] + adenosylcob(III)alamin + glutathione = S-adenosylglutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)

Left to rightBalance undeterminableRhea 63136

N-tetracosanoyl-taurine + H2O = tetracosanoate + taurine

Left to rightBalancedRhea 63140

N-(15Z-tetracosenoyl)-ethanolamine + H2O = (15Z)-tetracosenoate + ethanolamine

Left to rightBalancedRhea 63144

N-(9Z-octadecenoyl)-taurine + H2O = taurine + (9Z)-octadecenoate

Left to rightBalancedRhea 63148

an N-fatty acyl-taurine + H2O = taurine + a fatty acid

Direction not assertedBalance undeterminableRhea 63152

N-docosanoyl-taurine + H2O = docosanoate + taurine

Left to rightBalancedRhea 63156

N-(15Z-tetracosenoyl)-taurine + H2O = (15Z)-tetracosenoate + taurine

Left to rightBalancedRhea 63160

N-tricosanoyl-taurine + H2O = tricosanoate + taurine

Left to rightBalancedRhea 63164

fumarate + L-cysteine = S-(2-succino)-L-cysteine

Direction not assertedBalancedRhea 63168

(25S)-3-oxocholest-4-en-26-oyl-CoA = (25R)-3-oxocholest-4-en-26-oyl-CoA

Direction not assertedBalancedRhea 63172

(2S)-ibuprofenoyl-CoA = (2R)-ibuprofenoyl-CoA

Direction not assertedBalancedRhea 63176

NADPH + 2 O2 = 2 superoxide + NADP(+) + H(+)

Direction not assertedBalancedRhea 63180

NADH + 2 O2 = 2 superoxide + NAD(+) + H(+)

Direction not assertedBalancedRhea 63184

3,4-dihydroxybenzaldehyde + tyramine + AH2 = norbelladine + A + H2O

Direction not assertedBalancedRhea 63188

[(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + O2 = glycine betaine + phosphate + 2 H(+)

Direction not assertedBalancedRhea 63192

(10bR,4aS)-noroxomaritidine + NADPH + H(+) = (10bR,4aS)-oxomaritidine + NADP(+)

Direction not assertedBalancedRhea 63196

(10bS,4aR)-noroxomaritidine + NADPH + H(+) = (10bS,4aR)-oxomaritidine + NADP(+)

Direction not assertedBalancedRhea 63200

octadecanoyl-[ACP] + H2O = octadecanoate + holo-[ACP] + H(+)

Left to rightBalance undeterminableRhea 63204

5-amino-6-(D-ribitylamino)uracil + glyoxal = 5-(2-oxoethylideneamino)-6-(D-ribitylamino)uracil + H2O

Direction not assertedBalancedRhea 63208

5-amino-6-(D-ribitylamino)uracil + methylglyoxal = 5-(2-oxopropylideneamino)-6-(D-ribitylamino)uracil + H2O

Direction not assertedBalancedRhea 63212

7-cyano-7-carbaguanosine(15) in tRNA + L-lysine = 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA

Direction not assertedBalance undeterminableRhea 63216

7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine = archaeosine(15) in tRNA + L-1-piperideine-6-carboxylate + 5'-deoxyadenosine + L-methionine + 2 H(+)

Direction not assertedBalance undeterminableRhea 63220

2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[12-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl]-glycerol

Left to rightBalancedRhea 63224

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