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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

25,451–25,500 of 31,435, by identifier

a hydroperoxide + NADH + H(+) = an alcohol + NAD(+) + H2O
Direction not assertedBalance undeterminableRhea 62628
a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O
Left to rightBalance undeterminableRhea 62632
N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O
Direction not assertedBalance undeterminableRhea 62636
[mycoredoxin]-L-dithiol + a hydroperoxide = [mycoredoxin]-L-disulfide + an alcohol + H2O
Direction not assertedBalance undeterminableRhea 62640
(5Z,8Z)-eicosadienoate + O2 = (5S)-hydroperoxy-(6E,8Z)-eicosadienoate
Direction not assertedBalancedRhea 62644
(12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate
Direction not assertedBalancedRhea 62648

6 malonyl-CoA + acetyl-CoA + 6 H(+) = naphtopyrone YWA1 + 6 CO2 + 7 CoA + H2O

Direction not assertedBalancedRhea 62652

2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + dimethylallyl diphosphate = 2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol + diphosphate

Direction not assertedBalancedRhea 62656

2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol = (2'R)-atrovenetin

Direction not assertedBalancedRhea 62660

(2'R)-atrovenetin + S-adenosyl-L-methionine = deoxyherqueinone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 62664

deoxyherqueinone + NADPH + O2 + H(+) = herqueinone + NADP(+) + H2O

Direction not assertedBalancedRhea 62668

a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 62672

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-thiocarboxamide + 10-formyldihydrofolate = 6-thio-IMP + 7,8-dihydrofolate + H2O

Left to rightBalancedRhea 62676

naphtopyrone YWA1 = norrubrofusarin + H2O + H(+)

Direction not assertedBalancedRhea 62680

norrubrofusarin + S-adenosyl-L-methionine = rubrofusarin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 62684

4 norrubrofusarin + O2 = 2 ustilaginoidin A + 2 H2O

Direction not assertedBalancedRhea 62688

2 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + O2 = 2 tellimagrandin II + 2 H2O + 2 H(+)

Direction not assertedBalancedRhea 62692

4 tellimagrandin II + O2 = 2 cornusiin E + 2 H2O

Direction not assertedBalancedRhea 62696

naphtopyrone YWA1 + H2O = naphthalene-1,3,6,8-tetrol + acetoacetate + H(+)

Direction not assertedBalancedRhea 62700

glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine

Direction not assertedBalancedRhea 62704

(indol-3-yl)butanoate + UDP-alpha-D-glucose = 4-(indol-3-yl)butanoyl-beta-D-glucose + UDP

Direction not assertedBalancedRhea 62708

betaenone C + NADPH + O2 + H(+) = stemphyloxin I + NADP(+) + H2O

Direction not assertedBalancedRhea 62712

stemphyloxin I = stemphyloxin II

Direction not assertedBalancedRhea 62716

probetaenone I + 3 NADPH + 3 O2 + 3 H(+) = betaenone B + 3 NADP(+) + 3 H2O

Direction not assertedBalancedRhea 62720

(+)-premalbrancheamide + bromide + FADH2 + O2 = (+)-isomalbrancheamide C + FAD + 2 H2O

Direction not assertedBalancedRhea 62724

(+)-malbrancheamide B + bromide + FADH2 + O2 = (+)-malbrancheamide D + FAD + 2 H2O

Direction not assertedBalancedRhea 62728

(+)-isomalbrancheamide B + bromide + FADH2 + O2 = (+)-isomalbrancheamide D + FAD + 2 H2O

Direction not assertedBalancedRhea 62732

1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + dimethylallyl diphosphate = 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + diphosphate

Direction not assertedBalancedRhea 62736

(S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) = 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2

Direction not assertedBalancedRhea 62740

mevastatin + H2O = compactin diol lactone + (S)-2-methylbutanoate + H(+)

Direction not assertedBalancedRhea 62744

lovastatin + H2O = monacolin J + (S)-2-methylbutanoate + H(+)

Direction not assertedBalancedRhea 62748

pravastatin lactone + H2O = pravastatin diol lactone + (S)-2-methylbutanoate + H(+)

Direction not assertedBalancedRhea 62752

4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 62756

4alpha-hydroxymethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 62760

4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 62764

4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Left to rightBalance undeterminableRhea 62768

N-acetyl-D-phenylalanine = N-acetyl-L-phenylalanine

Direction not assertedBalancedRhea 62772

4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Left to rightBalance undeterminableRhea 62776

4alpha-methyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Left to rightBalance undeterminableRhea 62780

2 fonsecin B + NADPH + O2 + H(+) = bifonsecin B + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 62784

2 fonsecin B + NADPH + O2 + H(+) = aurasperone B + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 62788

2 rubrofusarin B + NADPH + O2 + 3 H(+) = nigerone + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 62792

2 rubrofusarin B + NADPH + O2 + H(+) = aurasperone A + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 62796

2 7-demethylsiderin + NADPH + O2 = orlandin + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 62800

2 7-demethylsiderin + NADPH + O2 = desertorin A + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 62804

2 julichrome Q6 + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = julichrome Q6-6 + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 62808

4 monapinone A + O2 = 2 dinapinone A + 2 H2O

Direction not assertedBalancedRhea 62812

4 monapinone E + O2 = 2 dinapinone E + 2 H2O

Direction not assertedBalancedRhea 62816

1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O

Left to rightBalance undeterminableRhea 62820

beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + GDP-beta-L-fucose = beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosamine + GDP + H(+)

Left to rightBalancedRhea 62824

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