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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

25,151–25,200 of 31,435, by identifier

cis-cis-nepetalactol + NAD(+) = cis-cis-nepetalactone + NADH + H(+)
Direction not assertedBalancedRhea 61424
cis-trans-nepetalactol + NAD(+) = cis-trans-nepetalactone + NADH + H(+)
Direction not assertedBalancedRhea 61428
(R)-8-oxocitronellyl enol + NADP(+) = (6E)-8-oxogeranial + NADPH + H(+)
Direction not assertedBalancedRhea 61432
ADP + H2O = AMP + phosphate + H(+)
Left to rightBalancedRhea 61436
S-(2-succino)-L-cysteine + acetyl-CoA = N-acetyl-S-(2-succino)-L-cysteine + CoA + H(+)
Direction not assertedBalancedRhea 61440
a tetracycline + NADPH + O2 + H(+) = an 11a-hydroxytetracycline + NADP(+) + H2O
Direction not assertedBalance undeterminableRhea 61444
tigecycline + NADPH + O2 + H(+) = 11a-hydroxytigecycline + NADP(+) + H2O

Direction not assertedBalancedRhea 61448

oxytetracycline + NADPH + O2 + H(+) = 11a-hydroxy-oxytetracycline + NADP(+) + H2O

Direction not assertedBalancedRhea 61452

7-chlorotetracycline + NADPH + O2 + H(+) = (1S,10S,10aS)-3-(CONH2)-9-Cl-1-(Me2N)-3,3a,4,10-(HO)4-10-Me-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracen-6-olate + CO + NADP(+) + H2O

Direction not assertedBalancedRhea 61456

a cytidine in RNA + S-adenosyl-L-methionine = a 5-methylcytidine in RNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 61460

a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 61464

a cytidine in tRNA + S-adenosyl-L-methionine = a 5-methylcytidine in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 61468

a sphingoid base + hexadecanoyl-CoA = an N-hexadecanoyl-sphingoid base + CoA + H(+)

Left to rightBalance undeterminableRhea 61472

a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+)

Left to rightBalance undeterminableRhea 61476

a very long-chain fatty acyl-CoA + a sphingoid base = an N-(very-long-chain fatty acyl)-sphingoid base + CoA + H(+)

Left to rightBalance undeterminableRhea 61480

a cytidine in rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 61484

cytidine(50) in tRNA + S-adenosyl-L-methionine = 5-methylcytidine(50) in tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 61488

an ultra-long-chain fatty acyl-CoA + a sphingoid base = an N-(ultra-long-chain-acyl)-sphingoid base + CoA + H(+)

Left to rightBalance undeterminableRhea 61492

an inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + GDP + H(+)

Direction not assertedBalance undeterminableRhea 61496

delphinidin + UDP-alpha-D-glucose = delphinidin 3-O-beta-D-glucoside + UDP

Direction not assertedBalancedRhea 61500

pelargonidin + UDP-alpha-D-glucose = pelargonidin 3-O-beta-D-glucoside + UDP

Direction not assertedBalancedRhea 61504

peonidin + UDP-alpha-D-glucose = peonidin 3-O-beta-D-glucoside + UDP

Direction not assertedBalancedRhea 61508

malvidin + UDP-alpha-D-glucose = malvidin 3-O-beta-D-glucoside + UDP

Direction not assertedBalancedRhea 61512

dopamine + AH2 = 3-tyramine + A + H2O

Direction not assertedBalancedRhea 61520

(8Z,11Z,14Z)-eicosatrienoate + O2 = (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate

Direction not assertedBalancedRhea 61524

an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol = an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base + a diacylglycerol

Left to rightBalance undeterminableRhea 61528

ent-kaur-16-ene + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = ent-kaur-16-en-19-oate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 61532

ent-kaur-16-ene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = ent-kaur-16-en-19-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 61536

ent-kaur-16-en-19-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = ent-kaur-16-en-19-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 61540

ent-kaur-16-en-19-al + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = ent-kaur-16-en-19-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 61544

ent-kaur-16-en-19-oate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = ent-7alpha-hydroxykaur-16-en-19-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 61548

ent-7alpha-hydroxykaur-16-en-19-oate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = gibberellin A12 aldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 61552

gibberellin A12 + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = gibberellin A15 + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 61556

gibberellin A15 + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = gibberellin A24 + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 61560

a tetracycline + NADPH + O2 + H(+) = a (1S,10aS)-3-(CONH2)-1-(Me2N)-3,3a,4,6-(HO)4-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracene + CO + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 61564

an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O = D-galactosamine + an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative

Direction not assertedBalance undeterminableRhea 61568

(11Z,14Z)-eicosadienoate + O2 = (15S)-hydroperoxy-(11Z,13E)-eicosadienoate

Direction not assertedBalancedRhea 61572

(4R,5R)-4,5-dihydroxycyclohex-2-ene-1-carbonyl-CoA + NADP(+) = (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 61576

(3S)-3-hydroxycyclohexane-1-carbonyl-CoA + NADP(+) = (5S)-5-hydroxycyclohex-1-ene-1-carbonyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 61580

cytidine(72) in tRNA(Cys) + S-adenosyl-L-methionine = 5-methylcytidine(72) in tRNA(Cys) + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 61584

amicoumacin A + ATP = amicoumacin A 2-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 61588

L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine + H2O = 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + 5'-deoxyadenosine + L-methionine + 2 H(+)

Direction not assertedBalance undeterminableRhea 61592

[DsbD protein]-dithiol + [thioredoxin]-disulfide = [DsbD protein]-disulfide + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 61596

[DsbD protein]-disulfide + [protein]-dithiol = [DsbB protein]-dithiol + [protein]-disulfide

Direction not assertedBalance undeterminableRhea 61600

[DsbB protein]-disulfide + [DsbA protein]-dithiol = [DsbA protein]-disulfide + [DsbB protein]-dithiol

Direction not assertedBalance undeterminableRhea 61604

[DsbB protein]-dithiol + a quinone = [DsbB protein]-disulfide + a quinol

Direction not assertedBalance undeterminableRhea 61608

7-deoxycylindrospermopsin + 2-oxoglutarate + O2 = 7-epi-cylindrospermopsin + succinate + CO2

Direction not assertedBalancedRhea 61612

L-proline betaine + NADH + O2 + H(+) = N-methyl-L-proline + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 61616

[(1->2)-beta-D-mannosyl](n) + GDP-alpha-D-mannose = [(1->2)-beta-D-mannosyl](n+1) + GDP + H(+)

Direction not assertedBalance undeterminableRhea 61620

cadaverine + 2-oxoglutarate = 5-aminopentanal + L-glutamate

Direction not assertedBalancedRhea 61624

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