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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

24,601–24,650 of 31,435, by identifier

L-serine + ADP = O-phospho-L-serine + AMP + H(+)
Direction not assertedBalancedRhea 59176
5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O = 2 AMP + H(+)
Direction not assertedBalancedRhea 59180
2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate
Direction not assertedBalancedRhea 59184
L-histidine = D-histidine
Direction not assertedBalancedRhea 59188
eicosanoate + ATP + H(+) = icosanoyl-AMP + diphosphate
Direction not assertedBalancedRhea 59192
icosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)
Direction not assertedBalance undeterminableRhea 59196
docosanoate + ATP + H(+) = docosanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 59200

docosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 59204

octadecanoate + ATP + H(+) = octadecanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 59208

octadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase] = octadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 59212

(indol-3-yl)acetate + H(+) = skatole + CO2

Direction not assertedBalancedRhea 59216

(2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + acetate + H(+)

Direction not assertedBalancedRhea 59220

(2E,6E,10E)-geranylgeranyl diphosphate = hydropyrene + diphosphate

Direction not assertedBalancedRhea 59224

6-sulfo-alpha-D-quinovose = 6-sulfo-beta-D-quinovose

Direction not assertedBalancedRhea 59228

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = hydropyrenol + diphosphate

Direction not assertedBalancedRhea 59232

(2E,6E,10E)-geranylgeranyl diphosphate = isoelisabethatriene + diphosphate

Direction not assertedBalancedRhea 59236

L-lysine + L-arginine = L-homoarginine + L-ornithine

Direction not assertedBalancedRhea 59240

3''-O-acetyl-ADP-D-ribose + H2O = ADP-D-ribose + acetate + H(+)

Left to rightBalancedRhea 59244

(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + (E)-4-coumaroyl-CoA = (R)-3-(4-hydroxyphenyl)lactoyl-CoA + (E)-4-coumarate

Direction not assertedBalancedRhea 59248

(R)-3-(indol-3-yl)lactate + (E)-3-(indol-3-yl)acryloyl-CoA = (R)-3-(indol-3-yl)lactoyl-CoA + (E)-3-(indol-3-yl)acrylate

Direction not assertedBalancedRhea 59252

Fe(III)-enterobactin + H2O = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H(+)

Direction not assertedBalancedRhea 59256

Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H2O + H(+) = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine

Direction not assertedBalancedRhea 59260

Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + H2O + H(+) = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + N-(2,3-dihydroxybenzoyl)-L-serine

Direction not assertedBalancedRhea 59264

N(6)-methyl-L-lysyl-[protein] + A + H2O = L-lysyl-[protein] + formaldehyde + AH2

Direction not assertedBalance undeterminableRhea 59268

L-cysteine = D-cysteine

Direction not assertedBalancedRhea 59272

L-glutamine = D-glutamine

Direction not assertedBalancedRhea 59276

L-asparagine = D-asparagine

Direction not assertedBalancedRhea 59280

beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + H2O = N-octadecanoylsphing-4-enine + D-glucose

Left to rightBalancedRhea 59284

beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose

Left to rightBalancedRhea 59288

beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine + H2O = N-octadecanoylsphing-4-enine + D-galactose

Left to rightBalancedRhea 59292

an N-acylglycine + 2 L-ascorbate + O2 = an N-acyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O

Direction not assertedBalance undeterminableRhea 59296

firefly D-luciferin + 3'-phosphoadenylyl sulfate = firefly D-sulfoluciferin + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 59300

firefly L-luciferin + 3'-phosphoadenylyl sulfate = firefly L-sulfoluciferin + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 59304

D-galactono-1,5-lactone + H2O = D-galactonate + H(+)

Direction not assertedBalancedRhea 59308

D-galactose + O2 = D-galactono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59312

D-cellobiose + O2 = D-cellobiono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59316

D-cellobiono-1,5-lactone + H2O = 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)

Direction not assertedBalancedRhea 59320

D-xylose + O2 = D-xylono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59324

D-xylono-1,5-lactone + H2O = D-xylonate + H(+)

Direction not assertedBalancedRhea 59328

1'-hydroxy-gamma-carotene + A = 1'-hydroxytorulene + AH2

Direction not assertedBalancedRhea 59332

1-hydroxy-all-trans-1,2-dihydro-neurosporene + A = demethylspheroidene + AH2

Direction not assertedBalancedRhea 59336

1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A = 1'-hydroxy-demethylspheroidene + AH2

Direction not assertedBalancedRhea 59340

D-maltose + O2 = D-maltobiono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59344

D-maltobiono-1,5-lactone + H2O = D-maltobionate + H(+)

Direction not assertedBalancedRhea 59348

beta-lactose + O2 = lactobiono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59352

lactobiono-1,5-lactone + H2O = lactobionate + H(+)

Direction not assertedBalancedRhea 59356

carnosine + H2O = beta-alanine + L-histidine

Left to rightBalancedRhea 59360

1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 9,10-epoxyoctadecanoate + 1-octadecanoyl-sn-glycero-3-phosphoserine + H(+)

Left to rightBalancedRhea 59364

1-octadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoserine + 10-hydroxyoctadecanoate + H(+)

Left to rightBalancedRhea 59368

1-hexadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 10-hydroxyoctadecanoate + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H(+)

Left to rightBalancedRhea 59372

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