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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

24,501–24,550 of 31,435, by identifier

pyridine 3-methanol + NADP(+) = pyridine-3-carbaldehyde + NADPH + H(+)
Direction not assertedBalancedRhea 58776
a 5'-end triphospho-guanosine-ribonucleotide-snRNA + S-adenosyl-L-methionine = a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + S-adenosyl-L-homocysteine
Left to rightBalance undeterminableRhea 58780
a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + 2-oxoglutarate + O2 = a 5'-end triphospho-guanosine-ribonucleotide-snRNA + formaldehyde + succinate + CO2 + H(+)
Direction not assertedBalance undeterminableRhea 58784
3 malonyl-CoA + acetyl-CoA + 2 S-adenosyl-L-methionine + NADPH + 2 H(+) = desmethylnectriapyrone + 2 S-adenosyl-L-homocysteine + 3 CO2 + NADP(+) + 4 CoA + H2O
Direction not assertedBalancedRhea 58788
Fe(III)-petrobactin(out) + ATP + H2O = Fe(III)-petrobactin(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 58792
a flavonol 7-O-beta-D-glucoside + malonyl-CoA = a flavonol 7-O-(6-O-malonyl-beta-D-glucoside) + CoA

? Direction not asserted

Balance undeterminable

Rhea 58796

3',3'-cGAMP + H2O = 5'-pApG-3' + H(+)

Direction not assertedBalancedRhea 58800

5'-pApG-3' + H2O = 5'-ApG-3' + phosphate

Direction not assertedBalancedRhea 58804

2',3'-cGAMP + 2 H2O = GMP + AMP + 2 H(+)

Left to rightBalancedRhea 58808

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + ATP + H2O = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 58812

UDP-N-acetyl-alpha-D-muramoyl-L-alanine + L-glutamate + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 58816

malonate + Na(+)(in) + H(+) = acetate + Na(+)(out) + CO2

Direction not assertedBalancedTransportRhea 58820

luteothin + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = aureothin + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 58824

(9S,10R)-epoxy-octadecanoate + H2O = 9R,10R-dihydroxyoctadecanoate

Direction not assertedBalancedRhea 58828

24-methylenecycloartanol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Direction not assertedBalance undeterminableRhea 58832

24-methylenecycloartanol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 58836

cholesterol sulfate + reduced [NADPH--hemoprotein reductase] + O2 = (24S)-hydroxycholesterol 3-sulfate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 58840

(6E)-8-hydroxygeranial + NAD(+) = (6E)-8-oxogeranial + NADH + H(+)

Direction not assertedBalancedRhea 58844

(6E)-8-hydroxygeraniol + NAD(+) = (6E)-8-hydroxygeranial + NADH + H(+)

Direction not assertedBalancedRhea 58848

(6E)-8-oxogeraniol + NAD(+) = (6E)-8-oxogeranial + NADH + H(+)

Direction not assertedBalancedRhea 58852

(6E)-8-hydroxygeraniol + NAD(+) = (6E)-8-oxogeraniol + NADH + H(+)

Direction not assertedBalancedRhea 58856

4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 58860

4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 58864

24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Direction not assertedBalance undeterminableRhea 58868

24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 58872

4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 58876

4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 58880

alpha-N-dichloroacetyl-p-aminophenylserinol + AH2 + 2 O2 = chloramphenicol + A + 2 H2O

Direction not assertedBalancedRhea 58884

4-aminobenzoate + AH2 + 2 O2 = 4-nitrobenzoate + A + 2 H2O

Direction not assertedBalancedRhea 58888

omega-hydroxy-beta-dihydromenaquinone-9 + 3'-phosphoadenylyl sulfate = omega-sulfo-beta-dihydromenaquinone-9 + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 58892

4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 58896

1-carboxybiuret + H2O = urea-1,3-dicarboxylate + NH4(+)

Direction not assertedBalancedRhea 58900

hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 8 (S)-methylmalonyl-CoA + 16 NADPH + 24 H(+) = C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 8 CO2 + 16 NADP(+) + 8 CoA + 8 H2O

Direction not assertedBalance undeterminableRhea 58904

hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 7 (S)-methylmalonyl-CoA + 14 NADPH + 21 H(+) = C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 7 CO2 + 14 NADP(+) + 7 CoA + 7 H2O

Direction not assertedBalance undeterminableRhea 58908

iron(III) dicitrate(out) + ATP + H2O = iron(III) dicitrate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 58912

squalene + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 58916

(3S,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol = (+)-medicarpin + H2O

Direction not assertedBalancedRhea 58920

(3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol = (-)-maackiain + H2O

Direction not assertedBalancedRhea 58924

(3R,4R)-7,2',4'-trihydroxyisoflavanol = (6aR,11aR)-3,9-dihydroxypterocarpan + H2O

Direction not assertedBalancedRhea 58928

4-nitrobenzoyl-CoA + 4 (S)-methylmalonyl-CoA + malonyl-CoA + 4 NADPH + 8 H(+) = demethylluteothin + 5 CO2 + 4 NADP(+) + 6 CoA + 3 H2O

Direction not assertedBalancedRhea 58932

2 (2E,6E,10E)-geranylgeranyl diphosphate + NADH + H(+) = all-trans-lycopaoctaene + 2 diphosphate + NAD(+)

Direction not assertedBalancedRhea 58936

(1R,2R,3R)-prephytoene diphosphate + NADH + H(+) = all-trans-lycopaoctaene + diphosphate + NAD(+)

Direction not assertedBalancedRhea 58940

4-nitrobenzoyl-CoA + 6 (S)-methylmalonyl-CoA + malonyl-CoA + 6 NADPH + 12 H(+) = demethyldeoxyspectinabilin + 7 CO2 + 6 NADP(+) + 8 CoA + 5 H2O

Direction not assertedBalancedRhea 58944

4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP + n H(+)

Direction not assertedBalance undeterminableRhea 58948

(20S)-protopanaxatriol + UDP-alpha-D-glucose = (20S)-ginsenoside Rh1 + UDP + H(+)

Direction not assertedBalancedRhea 58952

a ribonucleotide in RNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in RNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 58956

benzaldehyde + O2 + H2O = benzoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58960

hexanal + O2 + H2O = hexanoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58964

1-naphthaldehyde + O2 + H2O = 1-naphthoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58968

vanillin + O2 + H2O = vanillate + H2O2 + H(+)

Direction not assertedBalancedRhea 58972

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