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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

24,451–24,500 of 31,435, by identifier

dihydroprecondylocarpine acetate + NADP(+) = precondylocarpine acetate + NADPH + H(+)
Direction not assertedBalancedRhea 58576
dihydroprecondylocarpine acetate = catharanthine + acetate + H(+)
Direction not assertedBalancedRhea 58580
dihydroprecondylocarpine acetate = (-)-tabersonine + acetate + H(+)
Direction not assertedBalancedRhea 58584
dihydroprecondylocarpine acetate + NADPH = (+)-vincadifformine + acetate + NADP(+)
Direction not assertedBalancedRhea 58588
1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + NADPH + H(+) = 1-hexadecanoyl-2-(9-hydroxynonanoyl)-sn-glycero-3-phosphocholine + NADP(+)
Direction not assertedBalancedRhea 58592
FADH2 + H2O2 = FAD + 2 H2O + H(+)
Direction not assertedBalancedRhea 58596
N-(9Z-octadecenoyl)glycine + 2 L-ascorbate + O2 = N-(9Z-octadecenoyl)-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O

Direction not assertedBalancedRhea 58600

FAD + NADH + O2 + 2 H(+) = FADH2-C4alpha-hydroperoxide + NAD(+)

Direction not assertedBalancedRhea 58604

N-decanoylglycine + 2 L-ascorbate + O2 = N-decanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O

Direction not assertedBalancedRhea 58608

N-octanoylglycine + 2 L-ascorbate + O2 = N-octanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O

Direction not assertedBalancedRhea 58612

N-octanoyl-(2S)-hydroxyglycine = octanamide + glyoxylate

Direction not assertedBalancedRhea 58616

N-decanoyl-(2S)-hydroxyglycine = decanamide + glyoxylate

Direction not assertedBalancedRhea 58620

N-dodecanoyl-(2S)-hydroxyglycine = dodecanamide + glyoxylate

Direction not assertedBalancedRhea 58624

rifamycin SV + FADH2-C4alpha-hydroperoxide + NADPH + H(+) = rifamycin SV hemiaminal + FADH2 + NADP(+) + H2O

Direction not assertedBalancedRhea 58628

N-tetradecanoyl-(2S)-hydroxyglycine = tetradecamide + glyoxylate

Direction not assertedBalancedRhea 58632

N-(9Z-octadecenoyl)-(2S)-hydroxyglycine = (9Z)-octadecenamide + glyoxylate

Direction not assertedBalancedRhea 58636

a 5'-end 5'-phospho-ribonucleoside-RNA + 2 S-adenosyl-L-methionine = a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + 2 S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 58640

N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine = (9Z,12Z,15Z)-octadecatrienamide + glyoxylate

Direction not assertedBalancedRhea 58644

rifamycin SV hemiaminal = rifamycin SV ortho-naphthoquinone carboxamide + H(+)

Direction not assertedBalancedRhea 58648

rifamycin SV ortho-naphthoquinone carboxamide = rifamycin SV para-naphthoquinone carboxamide

Direction not assertedBalancedRhea 58652

a 5'-end 5'-phospho-ribonucleoside-RNA + S-adenosyl-L-methionine = a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 58656

a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-methionine = a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 58660

(S)-2-hydroxyglutarate + a quinone = a quinol + 2-oxoglutarate

Direction not assertedBalance undeterminableRhea 58664

3-deoxyfructose + NADP(+) = 3-deoxyglucosone + NADPH + H(+)

Direction not assertedBalancedRhea 58668

D-glucuronate = aldehydo-D-glucuronate

Direction not assertedBalancedRhea 58672

rifamycin SV + NADPH + O2 = rifamycin SV para-naphthoquinone carboxamide + NADP(+) + H2O

Direction not assertedBalancedRhea 58676

FADH2 + A = FAD + AH2 + H(+)

Direction not assertedBalancedRhea 58680

FAD + NADPH + O2 + 2 H(+) = FADH2-C4alpha-hydroperoxide + NADP(+)

Direction not assertedBalancedRhea 58684

rifamycin SV + NADH + O2 = rifamycin SV para-naphthoquinone carboxamide + NAD(+) + H2O

Direction not assertedBalancedRhea 58688

rifamycin SV + FADH2-C4alpha-hydroperoxide + NADH + H(+) = rifamycin SV hemiaminal + FADH2 + NAD(+) + H2O

Direction not assertedBalancedRhea 58692

rifampicin + NADPH + O2 = rifampicin para-naphthoquinone carboxamide + NADP(+) + H2O + H(+)

Direction not assertedBalancedRhea 58696

FADH2-C4alpha-hydroperoxide + rifampicin + NADPH = rifampicin hemiaminal + FADH2 + NADP(+) + H2O + H(+)

Direction not assertedBalancedRhea 58700

rifampicin hemiaminal = rifampicin ortho-naphthoquinone carboxamide

Direction not assertedBalancedRhea 58704

rifampicin ortho-naphthoquinone carboxamide = rifampicin para-naphthoquinone carboxamide

Direction not assertedBalancedRhea 58708

rifampicin + NADH + O2 = rifampicin para-naphthoquinone carboxamide + NAD(+) + H2O + H(+)

Direction not assertedBalancedRhea 58712

FADH2-C4alpha-hydroperoxide + rifampicin + NADH = rifampicin hemiaminal + FADH2 + NAD(+) + H2O + H(+)

Direction not assertedBalancedRhea 58716

(S)-nicotine + NADPH + O2 = trans-(S)-nicotine N(1')-oxide + NADP(+) + H2O

Left to rightBalancedRhea 58720

adenosine(4220) in 28S rRNA + S-adenosyl-L-methionine = N(6)-methyladenosine(4220) in 28S rRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 58724

adenosine in rRNA + S-adenosyl-L-methionine = N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 58728

5-methyl-CTP + H2O = 5-methyl-CMP + diphosphate + H(+)

Direction not assertedBalancedRhea 58732

5-methyl-UTP + H2O = 5-methyl-UMP + diphosphate + H(+)

Direction not assertedBalancedRhea 58736

psi-UTP + H2O = psi-UMP + diphosphate + H(+)

Direction not assertedBalancedRhea 58740

N(7)-methyl-GTP + H2O = N(7)-methyl-GMP + diphosphate + H(+)

Direction not assertedBalancedRhea 58744

desmethylnectriapyrone + S-adenosyl-L-methionine = nectriapyrone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 58748

1-hexadecanoyl-2-(7-oxoheptanoyl)-sn-glycero-3-phosphocholine + NADPH + H(+) = 1-hexadecanoyl-2-(7-hydroxyheptanoyl)-sn-glycero-3-phosphocholine + NADP(+)

Direction not assertedBalancedRhea 58752

1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + NADPH + H(+) = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+)

Direction not assertedBalancedRhea 58756

1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + NADPH + H(+) = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + NADP(+)

Direction not assertedBalancedRhea 58760

1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + NADPH + H(+) = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+)

Direction not assertedBalancedRhea 58764

1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + NADPH + H(+) = 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)

Direction not assertedBalancedRhea 58768

1-O-hexadecyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + NADPH + H(+) = 1-O-hexadecyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)

Direction not assertedBalancedRhea 58772

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