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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

24,051–24,100 of 31,435, by identifier

androst-5-en-3beta,17beta-diol + NAD(+) = 17beta-hydroxy-androst-5-en-3-one + NADH + H(+)
Direction not assertedBalancedRhea 56932
17beta-hydroxy-androst-5-en-3-one = testosterone
Direction not assertedBalancedRhea 56936
5-(methylsulfanyl)-D-ribulose 1-phosphate = 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate
Direction not assertedBalancedRhea 56940
D-ribulose 5-phosphate + AH2 = 1-deoxy-D-xylulose 5-phosphate + A + H2O
Direction not assertedBalancedRhea 56944
UTP + pyruvate = phosphoenolpyruvate + UDP + H(+)
Direction not assertedBalancedRhea 56948
CTP + pyruvate = CDP + phosphoenolpyruvate + H(+)
Direction not assertedBalancedRhea 56952
ITP + pyruvate = IDP + phosphoenolpyruvate + H(+)

Direction not assertedBalancedRhea 56956

a ribonucleoside 5'-triphosphate + pyruvate = a ribonucleoside 5'-diphosphate + phosphoenolpyruvate + H(+)

Direction not assertedBalance undeterminableRhea 56960

a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate = a 2'-deoxyribonucleoside 5'-diphosphate + phosphoenolpyruvate + H(+)

Direction not assertedBalance undeterminableRhea 56964

dCTP + pyruvate = dCDP + phosphoenolpyruvate + H(+)

Direction not assertedBalancedRhea 56968

(R)-3-hydroxy-2-methylpropanoate + NAD(+) = (R)-2-methyl-3-oxopropanoate + NADH + H(+)

Direction not assertedBalancedRhea 56972

4-methylphenol + 2 oxidized [azurin] + H2O = 4-hydroxybenzyl alcohol + 2 reduced [azurin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 56976

4-hydroxybenzyl alcohol + 2 oxidized [azurin] = 2 reduced [azurin] + 4-hydroxybenzaldehyde + 2 H(+)

Direction not assertedBalance undeterminableRhea 56980

(2E,6E)-farnesyl diphosphate + H2O = (6E)-nerolidol + diphosphate

Direction not assertedBalancedRhea 56984

germacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 56988

6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = (+)-costunolide + H2O

Direction not assertedBalancedRhea 56992

aldehydo-D-apiose = apulose

Direction not assertedBalancedRhea 56996

streptothricin F + acetyl-CoA = N(beta)-acetylstreptothricin F + CoA + H(+)

Direction not assertedBalancedRhea 57000

streptothricin D + acetyl-CoA = N(beta)-acetylstreptothricin D + CoA + H(+)

Direction not assertedBalancedRhea 57004

5,5'-dehydrodivanillate + NADH + O2 + H(+) = 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 57008

a menaquinone + sulfite + H2O = a menaquinol + sulfate

Direction not assertedBalance undeterminableRhea 57012

3,6-dichloro-2-methoxybenzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 3,6-dichlorosalicylate + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 57016

apulose + ATP = apulose 4-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 57020

apulose 4-phosphate + D-glyceraldehyde 3-phosphate = D-xylulose 5-phosphate + dihydroxyacetone phosphate

Direction not assertedBalancedRhea 57024

N-methylnicotinate + FADH2 + O2 = (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FAD + H(+)

Direction not assertedBalancedRhea 57028

(E)-2-((N-methylformamido) methylene)succinate + 2 H2O + H(+) = succinate semialdehyde + methylamine + formate + CO2

Direction not assertedBalancedRhea 57032

[(1->6)-alpha-D-glucosyl](n) + sucrose = (1->3)-alpha-D-glucosyl-[(1->6)-alpha-D-glucosyl](n) + D-fructose

Direction not assertedBalance undeterminableRhea 57036

aldehydo-D-apiose = D-apiofuranose

Direction not assertedBalancedRhea 57040

D-apionate + NAD(+) = 3-oxoisoapionate + NADH + H(+)

Direction not assertedBalancedRhea 57044

cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] + AH2 + ATP = 2-thiocytidine(32) in tRNA + L-cysteinyl-[cysteine desulfurase] + A + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 57048

3-oxoisoapionate + H(+) = L-erythrulose + CO2

Direction not assertedBalancedRhea 57052

D-apiofuranose + NAD(+) = D-apionolactone + NADH + H(+)

Direction not assertedBalancedRhea 57056

2''-O-acetyl-ADP-D-ribose + H2O = ADP-D-ribose + acetate + H(+)

Left to rightBalancedRhea 57060

D-apionolactone + H2O = D-apionate + H(+)

Direction not assertedBalancedRhea 57064

3-oxoisoapionate + ATP = 3-oxoisoapionate 4-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 57068

3-oxoisoapionate 4-phosphate + H(+) = L-erythrulose 1-phosphate + CO2

Direction not assertedBalancedRhea 57072

3-oxoisoapionate 4-phosphate + H2O = (2R)-3-phosphoglycerate + glycolate + H(+)

Direction not assertedBalancedRhea 57076

S-methyl-1-thio-D-xylulose 5-phosphate + glutathione = S-(methylsulfanyl)glutathione + 1-deoxy-D-xylulose 5-phosphate

Direction not assertedBalancedRhea 57080

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 57084

an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 57088

S-(methylsulfanyl)glutathione + AH2 = methanethiol + glutathione + A

Direction not assertedBalancedRhea 57092

S-methyl-1-thio-D-xylulose 5-phosphate + AH2 = 1-deoxy-D-xylulose 5-phosphate + methanethiol + A

Direction not assertedBalancedRhea 57096

5-(methylsulfanyl)-D-ribulose 1-phosphate = S-methyl-1-thio-D-xylulose 5-phosphate

Direction not assertedBalancedRhea 57100

[(1->4)-alpha-D-galacturonosyl](n) = 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate + [(1->4)-alpha-D-galacturonosyl](n-2)

Direction not assertedBalance undeterminableRhea 57104

1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 57108

1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine

Direction not assertedBalancedRhea 57112

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 57116

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 57120

2-oxoglutaramate = 2-hydroxy-5-oxoproline

Direction not assertedBalancedRhea 57124

2 oxidized [azurin] + tyramine + H2O = 2 reduced [azurin] + (4-hydroxyphenyl)acetaldehyde + NH4(+) + 2 H(+)

Direction not assertedBalance undeterminableRhea 57128

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