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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,751–23,800 of 31,435, by identifier

hydrogen sulfide + glycine + NAD(+) = ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + H(+)
Direction not assertedBalancedRhea 55704
[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 55708
3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
Left to rightBalancedRhea 55712
(S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)
Left to rightBalancedRhea 55716
17-(4-hydroxyphenyl)heptadecanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate
Direction not assertedBalance undeterminableRhea 55720
17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55724

19-(4-hydroxyphenyl)nonadecanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP = 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 55728

19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55732

alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose = [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 55736

oleuropein + H2O = oleuropein aglycone + D-glucose

Direction not assertedBalancedRhea 55740

coenzyme B + 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 4 H(+) = coenzyme M-coenzyme B heterodisulfide + 2 reduced coenzyme F420-(gamma-L-Glu)(n) + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 55744

coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 55748

coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 2 CO2 = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 55752

an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + 2-oxoglutarate + O2 = a 2-hydroxyornithine lipid + succinate + CO2

Direction not assertedBalance undeterminableRhea 55756

a lyso-ornithine lipid + a fatty acyl-[ACP] = an N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine lipid + holo-[ACP]

Direction not assertedBalance undeterminableRhea 55760

1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O = 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol

Direction not assertedBalancedRhea 55764

all-trans-retinoate + UDP-alpha-D-glucuronate = all-trans-retinoyl-1-O-(beta-D-glucuronate) + UDP

Left to rightBalancedRhea 55768

a jasmonate + an L-alpha-amino acid + ATP = a jasmonyl-L-amino acid + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 55772

all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate = all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + UDP + H(+)

Left to rightBalancedRhea 55776

all-trans-5,6-epoxyretinoate + UDP-alpha-D-glucuronate = all-trans-5,6-epoxyretinoyl-1-O-(beta-D-glucuronate) + UDP

Direction not assertedBalancedRhea 55780

all-trans-4-oxoretinoate + UDP-alpha-D-glucuronate = all-trans-4-oxoretinoate 1-O-(beta-D-glucuronate) + UDP

Direction not assertedBalancedRhea 55784

acetone + NADH + O2 + H(+) = hydroxyacetone + NAD(+) + H2O

Direction not assertedBalancedRhea 55788

butan-2-one + NADH + O2 + H(+) = 1-hydroxy-2-butanone + NAD(+) + H2O

Direction not assertedBalancedRhea 55792

phenol + NADH + O2 + H(+) = hydroquinone + NAD(+) + H2O

Direction not assertedBalancedRhea 55796

an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyleicosasphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 55800

(R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O = (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 55804

a dihydroceramide + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 55808

a bacteriochlorophyllide d + 2 S-adenosyl-L-methionine + H2O = a bacteriochlorophyllide f + 2 5'-deoxyadenosine + 2 L-methionine + 2 H(+)

Direction not assertedBalance undeterminableRhea 55812

a bacteriochlorophyllide d + S-adenosyl-L-methionine + H2O = a 7(1)-hydroxybacteriochlorophyllide d + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 55816

a 7(1)-hydroxybacteriochlorophyllide d + S-adenosyl-L-methionine + H2O = a 7(1),7(1)-dihydroxybacteriochlorophyllide d + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 55820

a 7(1),7(1)-dihydroxybacteriochlorophyllide d = a bacteriochlorophyllide f + H2O

Direction not assertedBalance undeterminableRhea 55824

cortisol + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxycortisol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 55828

cortisone + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxycortisone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 55832

calcitriol + UDP-alpha-D-glucuronate = calcitriol 25-O-(beta-D-glucuronide) + UDP + H(+)

Left to rightBalancedRhea 55836

calcidiol + UDP-alpha-D-glucuronate = calcidiol 25-O-(beta-D-glucuronide) + UDP + H(+)

Left to rightBalancedRhea 55840

calcidiol + UDP-alpha-D-glucuronate = calcidiol 3-O-(beta-D-glucuronide) + UDP + H(+)

Left to rightBalancedRhea 55844

[(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA = [(2->6)-alpha-D-glucosyl-(1->4)-N,7-O-diacetyl-alpha-D-neuraminosyl](n) + n CoA

Direction not assertedBalance undeterminableRhea 55848

[(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA = [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA

Direction not assertedBalance undeterminableRhea 55852

all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-18-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 55856

all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-5,6-epoxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 55860

(S)-lactate + O2 = pyruvate + H2O2

Direction not assertedBalancedRhea 55868

N,N-dimethyl-1,4-phenylenediamine + anthranilate + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH + 2 H(+)

Direction not assertedBalancedRhea 55872

apo-[aequorin] + coelenterazine = apo-[aequorin]--coelenterazine

Direction not assertedBalance undeterminableRhea 55876

apo-[aequorin]--coelenterazine + O2 = [aequorin]

Direction not assertedBalance undeterminableRhea 55880

[aequorin] + 3 Ca(2+) = [aequorin]--dioxetanone

Direction not assertedBalance undeterminableRhea 55884

[aequorin]--dioxetanone = excited state-[aequorin] + CO2

Direction not assertedBalance undeterminableRhea 55888

a 2-(all-trans-polyprenyl)phenol + NADPH + O2 + H(+) = a 3-(all-trans-polyprenyl)benzene-1,2-diol + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 55892

L-tryptophan + FADH2 + chloride + O2 = 5-chloro-L-tryptophan + FAD + 2 H2O

Direction not assertedBalancedRhea 55896

L-tryptophan + FADH2 + chloride + O2 = 6-chloro-L-tryptophan + FAD + 2 H2O

Direction not assertedBalancedRhea 55900

7-chloro-L-tryptophan + FADH2 + chloride + O2 = 6,7-dichloro-L-tryptophan + FAD + 2 H2O

Direction not assertedBalancedRhea 55904

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