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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,701–23,750 of 31,435, by identifier

ent-cassa-12,15-dien-2beta,3beta-ol + reduced [NADPH--hemoprotein reductase] + O2 = ent-3beta-hydroxycassa-12,15-dien-2-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Direction not assertedBalance undeterminableRhea 55500
(5S,9S,10S)-drim-7-en-11-ol + reduced [NADPH--hemoprotein reductase] + O2 = (5S,10S)-(9R)-7-drimene-11,12-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 55504
cucurbitadienol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 11-oxocucurbitadienol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 55508
cucurbitadienol + reduced [NADPH--hemoprotein reductase] + O2 = 11-hydroxycucurbitadienol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 55512
11-hydroxycucurbitadienol + reduced [NADPH--hemoprotein reductase] + O2 = 11-oxocucurbitadienol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Direction not assertedBalance undeterminableRhea 55516
3 isopentenyl diphosphate + dimethylallyl diphosphate = nerylneryl diphosphate + 3 diphosphate

Direction not assertedBalancedRhea 55520

L-dopa + O2 + H2O + H(+) = 3,4-dihydroxyphenylacetaldehyde + H2O2 + NH4(+) + CO2

Direction not assertedBalancedRhea 55524

L-tyrosine + O2 + H2O + H(+) = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+) + CO2

Direction not assertedBalancedRhea 55528

L-phenylalanine + O2 + H2O + H(+) = 2-phenylacetaldehyde + H2O2 + NH4(+) + CO2

Direction not assertedBalancedRhea 55532

an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose = a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)

Direction not assertedBalance undeterminableRhea 55536

N2 + 12 reduced [2Fe-2S]-[ferredoxin] + 40 ATP + 40 H2O = 3 H2 + 12 oxidized [2Fe-2S]-[ferredoxin] + 2 NH4(+) + 40 ADP + 40 phosphate + 26 H(+)

Direction not assertedBalance undeterminableRhea 55540

L-lysyl-[citrate synthase] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 55544

N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 55548

N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 55552

a hydroperoxyeicosatetraenoate = an oxoeicosatetraenoate + H2O

Left to rightBalancedRhea 55556

a hydroperoxyeicosatetraenoate = a hydroxy-epoxy-eicosatetraenoate

Left to rightBalancedRhea 55560

4-hydroxytryptamine + ATP = norbaeocystin + ADP + H(+)

Direction not assertedBalancedRhea 55564

norbaeocystin + 2 S-adenosyl-L-methionine = psilocybin + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 55568

norbaeocystin + S-adenosyl-L-methionine = baeocystin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 55572

baeocystin + S-adenosyl-L-methionine = psilocybin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 55576

L-glutamine + ATP + H2O = N(5)-phospho-L-glutamine + AMP + phosphate + 2 H(+)

Direction not assertedBalancedRhea 55580

an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 55584

an N-acyl-sphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol-1-phosphoceramide + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 55588

2 (3R)-hydroxydecanoyl-[ACP] + H2O = (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + 2 holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 55592

a globoside NOR1 + UDP-N-acetyl-alpha-D-galactosamine = a globoside NORint + UDP + H(+)

Direction not assertedBalance undeterminableRhea 55596

an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose = a mannosylinositol-1-phosphoceramide + GDP + H(+)

Direction not assertedBalance undeterminableRhea 55600

a mannosylinositol-1-phospho-N-acyl-sphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol phosphomannosylnositol-1-phospho-N-acylsphingoid base + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 55604

a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol phosphomannosylnositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 55608

an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + H2O = 1-methyladenine + a 2'-deoxyribose 5'-monophosphate in double-stranded DNA + H(+)

Direction not assertedBalance undeterminableRhea 55612

a carotenoid psi-end derivative = a carotenoid epsilon-end derivative

Direction not assertedBalance undeterminableRhea 55616

a carotenoid psi-end derivative = a carotenoid beta-end derivative

Direction not assertedBalance undeterminableRhea 55620

an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O = 3-methylcytosine + a 2'-deoxyribose 5'-monophosphate in double-stranded DNA + H(+)

Direction not assertedBalance undeterminableRhea 55624

1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)

Left to rightBalancedRhea 55632

C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + ATP + H2O = C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + AMP + phosphate + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 55636

C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate = C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55640

C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + ATP = C-terminal S-cyanate-L-cysteinyl-[HypE protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 55644

validoxylamine A + 2-oxoglutarate + O2 = validoxylamine B + succinate + CO2 + H(+)

Direction not assertedBalancedRhea 55648

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate

Left to rightBalance undeterminableRhea 55652

a carotenoid beta-end derivative + 2 A = a carotenoid chi-end derivative + 2 AH2

Direction not assertedBalance undeterminableRhea 55656

all-trans-beta-carotene + 2 AH2 + 2 O2 = echinenone + 2 A + 3 H2O

Direction not assertedBalancedRhea 55660

echinenone + 2 AH2 + 2 O2 = canthaxanthin + 2 A + 3 H2O

Direction not assertedBalancedRhea 55664

11-cis-retinol--[retinol-binding protein] + NAD(+) = 11-cis-retinal--[retinol-binding protein] + NADH + H(+)

Direction not assertedBalance undeterminableRhea 55668

4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP + n H(+)

Direction not assertedBalance undeterminableRhea 55672

chorismate + NH4(+) = (2S)-2-amino-4-deoxychorismate + H2O

Direction not assertedBalancedRhea 55676

(2S)-2-amino-4-deoxychorismate = anthranilate + pyruvate + H(+)

Direction not assertedBalancedRhea 55680

chorismate + NH4(+) = 4-amino-4-deoxychorismate + H2O

Direction not assertedBalancedRhea 55684

an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + H2O = 1D-myo-inositol 1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+)

Direction not assertedBalance undeterminableRhea 55688

an inositol-1-phosphoceramide + H2O = 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)

Direction not assertedBalance undeterminableRhea 55692

a mannosylinositol-1-phospho-N-acyl-sphingoid base + H2O = mannosylinositol-1-phosphate + an N-acyl-sphingoid base + H(+)

Direction not assertedBalance undeterminableRhea 55696

an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O = mannosyldiinositol-1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+)

Direction not assertedBalance undeterminableRhea 55700

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