Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,851–22,900 of 31,435, by identifier

13-(9Z-octadecenoyloxy)-octadecanoate + H2O = 13-hydroxy-octadecanoate + (9Z)-octadecenoate + H(+)
Left to rightBalancedRhea 52064
9-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 9-hydroxy-octadecanoate + H(+)
Left to rightBalancedRhea 52068
12-(9Z-hexadecenoyloxy)-octadecanoate + H2O = 12-hydroxyoctadecanoate + (9Z)-hexadecenoate + H(+)
Left to rightBalancedRhea 52072
13-(9Z-hexadecenoyloxy)-octadecanoate + H2O = 13-hydroxy-octadecanoate + (9Z)-hexadecenoate + H(+)
Left to rightBalancedRhea 52076
12-octadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + octadecanoate + H(+)
Left to rightBalancedRhea 52080
13-octadecanoyloxy-octadecanoate + H2O = 13-hydroxy-octadecanoate + octadecanoate + H(+)
Left to rightBalancedRhea 52084
5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoate + ATP + CoA = 5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 52088

5-(9Z-hexadecenoyloxy)-octadecanoate + H2O = 5-hydroxy-octadecanoate + (9Z)-hexadecenoate + H(+)

Left to rightBalancedRhea 52092

9-octadecanoyloxy-octadecanoate + H2O = 9-hydroxy-octadecanoate + octadecanoate + H(+)

Left to rightBalancedRhea 52096

5-(9Z-octadecenoyloxy)-octadecanoate + H2O = 5-hydroxy-octadecanoate + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 52100

a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)

Left to rightBalance undeterminableRhea 52104

5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 52108

12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 52112

15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP + CoA = 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 52116

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = (19R,20S)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52120

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52124

a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 52128

a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O = a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 52132

a 5'-end guanosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + GMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 52136

a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O = a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 52140

3-phosphonopyruvate + acetyl-CoA + H2O = (R)-2-(phosphonomethyl)malate + CoA + H(+)

Direction not assertedBalancedRhea 52144

a (Z)-omega-(methylsulfanyl)alkyl-thiohydroximate + UDP-alpha-D-glucose = an aliphatic (Z)-desulfo-glucosinolate + UDP

Direction not assertedBalance undeterminableRhea 52148

(Z)-2-(indol-3-yl)-1-thioacetohydroximate + UDP-alpha-D-glucose = (Z)-indolylmethyl desulfoglucosinolate + UDP

Direction not assertedBalancedRhea 52152

(E)-phenylacetaldehyde oxime + reduced [NADPH--hemoprotein reductase] + O2 = (R)-mandelonitrile + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 52156

(E)-phenylacetaldehyde oxime = (Z)-phenylacetaldehyde oxime

Direction not assertedBalancedRhea 52160

phenylacetonitrile + reduced [NADPH--hemoprotein reductase] + O2 = (R)-mandelonitrile + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52164

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52168

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52172

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52176

(E)-(indol-3-yl)acetaldehyde oxime + glutathione + reduced [NADPH--hemoprotein reductase] + O2 = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 52180

(E)-(indol-3-yl)acetaldehyde oxime + reduced [NADPH--hemoprotein reductase] + O2 = 1-aci-nitro-2-(1H-indol-3-yl)ethane + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52184

1-aci-nitro-2-(1H-indol-3-yl)ethane + glutathione = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H2O

Direction not assertedBalancedRhea 52188

(E)-phenylacetaldehyde oxime + glutathione + reduced [NADPH--hemoprotein reductase] + O2 = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 52192

(E)-phenylacetaldehyde oxime + reduced [NADPH--hemoprotein reductase] + O2 = 1-aci-nitro-2-(phenyl)ethane + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52196

1-aci-nitro-2-(phenyl)ethane + glutathione = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H2O

Direction not assertedBalancedRhea 52200

butachlor + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = butyl formate + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 52204

alachlor + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = methyl formate + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 52208

acetochlor + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = N-(2-ethyl-6-methylphenyl)-2-chloroacetamide + ethyl formate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 52212

[(1''->2')-ADP-alpha-D-ribose](n) + H2O = [(1''->2')-ADP-alpha-D-ribose](n-1) + ADP-D-ribose

Left to rightBalance undeterminableRhea 52216

heme b + 3 AH2 + 3 O2 + 3 H(+) = biliverdin IXdelta + CO + Fe(2+) + 3 A + 3 H2O

Direction not assertedBalancedRhea 52224

heme b + 3 AH2 + 3 O2 + 2 H(+) = biliverdin IXbeta + CO + Fe(2+) + 3 A + 3 H2O

Direction not assertedBalancedRhea 52228

heme b + 3 AH2 + 3 O2 + 2 H(+) = mycobilin a + Fe(2+) + 3 A + 3 H2O

Direction not assertedBalancedRhea 52232

heme b + 3 AH2 + 3 O2 + 2 H(+) = mycobilin b + Fe(2+) + 3 A + 3 H2O

Direction not assertedBalancedRhea 52236

2 Mn(2+) + O2 + 2 H2O = 2 MnO2 + 4 H(+)

Direction not assertedBalancedRhea 52240

4 Mn(2+) + O2 + 4 H(+) = 4 Mn(3+) + 2 H2O

Direction not assertedBalancedRhea 52244

4 Mn(3+) + O2 + 6 H2O = 4 MnO2 + 12 H(+)

Direction not assertedBalancedRhea 52248

a bacteriochlorophyllide c + 2 S-adenosyl-L-methionine + H2O = a bacteriochlorophyllide e + 2 5'-deoxyadenosine + 2 L-methionine + 2 H(+)

Direction not assertedBalance undeterminableRhea 52252

a 7(1)-hydroxybacteriochlorophyllide c + S-adenosyl-L-methionine + H2O = a 7(1),7(1)-dihydroxybacteriochlorophyllide c + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 52256

a 7(1),7(1)-dihydroxybacteriochlorophyllide c = a bacteriochlorophyllide e + H2O

Direction not assertedBalance undeterminableRhea 52260

3-(aminomethyl)indole + 2 S-adenosyl-L-methionine = gramine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 52264

Page 458 of 629