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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,101–22,150 of 31,435, by identifier

[thyroglobulin]-3-iodo-L-tyrosine + [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O
Direction not assertedBalance undeterminableRhea 48968
phosphite(out) + ATP + H2O = phosphite(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 48972
5-methyl-phenazine-1-carboxylate + NADH + O2 + 2 H(+) = pyocyanin + CO2 + NAD(+) + H2O
Direction not assertedBalancedRhea 48976
3,4-dichlorocatechol + O2 = (2Z,4Z)-2,3-dichloromuconate + 2 H(+)
Direction not assertedBalancedRhea 48980
(2,4-dichlorophenoxy)acetate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + glyoxylate + succinate + CO2
Direction not assertedBalancedRhea 48984
1,3,7-trimethylurate + NADH + O2 + H(+) = 1,3,7-trimethyl-5-hydroxyisourate + NAD(+) + H2O
Direction not assertedBalancedRhea

48992

3-methylcatechol + O2 = 2-hydroxy-6-oxo-2,4-heptadienoate + H(+)

Direction not assertedBalancedRhea 48996

aurachin C + NADH + O2 + H(+) = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD(+) + H2O

Direction not assertedBalancedRhea 49000

aurachin C + NADPH + O2 + H(+) = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP(+) + H2O

Direction not assertedBalancedRhea 49004

aurachin C + NADPH + O2 + H(+) = aurachin C epoxide + NADP(+) + H2O

Direction not assertedBalancedRhea 49008

aurachin C + NADH + O2 + H(+) = aurachin C epoxide + NAD(+) + H2O

Direction not assertedBalancedRhea 49012

aurachin C epoxide = 2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one

Direction not assertedBalancedRhea 49016

2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide

Direction not assertedBalancedRhea 49020

L-tryptophan + O2 = 2-iminio-3-(indol-3-yl)propanoate + H2O2

Direction not assertedBalancedRhea 49024

(-)-bursehernin + reduced [NADPH--hemoprotein reductase] + O2 = (-)-5'-demethylyatein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 49028

(-)-4'-desmethyl-deoxypodophyllotoxin + reduced [NADPH--hemoprotein reductase] + O2 = 4'-demethylepipodophyllotoxin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 49032

(-)-pluviatolide + S-adenosyl-L-methionine = (-)-bursehernin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49036

(-)-5'-demethylyatein + S-adenosyl-L-methionine = (-)-yatein + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49040

protoasukamycin + NADH + O2 + H(+) = 4-hydroxyprotoasukamycin + NAD(+) + H2O

Direction not assertedBalancedRhea 49044

25-hydroxyvitamin D2 + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 1alpha,25-dihydroxyvitamin D2 + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 49048

asperlicin C + NADH + O2 + H(+) = asperlicin E + NAD(+) + H2O

Direction not assertedBalancedRhea 49052

asperlicin C + NADPH + O2 + H(+) = asperlicin E + NADP(+) + H2O

Direction not assertedBalancedRhea 49056

a long-chain alkane + FMNH2 + O2 = a long chain fatty alcohol + FMN + H2O + H(+)

Direction not assertedBalance undeterminableRhea 49060

secalciferol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = calcitetrol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 49064

25-hydroxy-24-oxocalciol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (1S)-1,25-dihydroxy-24-oxocalciol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 49068

dibenzothiophene + 2 FMNH2 + 2 O2 = dibenzothiophene 5,5-dioxide + 2 FMN + 2 H2O + 2 H(+)

Direction not assertedBalancedRhea 49072

dibenzothiophene + FMNH2 + O2 = dibenzothiophene 5-oxide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 49076

dibenzothiophene 5-oxide + FMNH2 + O2 = dibenzothiophene 5,5-dioxide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 49080

(-)-matairesinol + reduced [NADPH--hemoprotein reductase] + O2 = (-)-pluviatolide + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 49084

squalene + FAD + H2O + H(+) = hydroxysqualene + FADH2

Direction not assertedBalancedRhea 49088

1-hexadecanoyl-sn-glycero-3-phosphate + H2O = sn-glycerol 3-phosphate + hexadecanoate + H(+)

Left to rightBalancedRhea 49092

Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine + H2O = 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 3 L-methionine + 4 H(+)

Direction not assertedBalancedRhea 49096

Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine + H2O = Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 49100

Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine = Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 49104

Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine = 3,8-divinyl protochlorophyllide a + 5'-deoxyadenosine + L-methionine + 2 H(+)

Direction not assertedBalancedRhea 49108

phenazine-1-carboxylate + S-adenosyl-L-methionine = 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 49112

protodeoxyviolaceinate + NADPH + O2 + H(+) = deoxyviolaceinate + NADP(+) + H2O

Direction not assertedBalancedRhea 49116

protoviolaceinate + NADPH + O2 + H(+) = violaceinate + NADP(+) + H2O

Direction not assertedBalancedRhea 49120

protodeoxyviolaceinate + NADPH + O2 + H(+) = protoviolaceinate + NADP(+) + H2O

Direction not assertedBalancedRhea 49124

N-acetyl-demethyl-L-phosphinothricin + AH2 + 2 S-adenosyl-L-methionine = N-acetyl-L-phosphinothricin + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 49128

an adenosine in tRNA + S-adenosyl-L-methionine = an N(1)-methyladenosine in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 49132

L-methionyl-[protein] + NADPH + O2 + H(+) = L-methionyl-S-oxide-[protein] + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 49136

dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) = dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 49140

dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + 2-oxoglutarate = dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + L-glutamate

Direction not assertedBalancedRhea 49144

dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-forosamine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 49148

dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine = dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49152

dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine = dTDP-alpha-D-forosamine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49156

1,4-cineole + reduced [NADPH--hemoprotein reductase] + O2 = 2-exo-hydroxy-1,4-cineole + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 49160

a bacteriochlorophyllide c + S-adenosyl-L-methionine + H2O = a 7(1)-hydroxybacteriochlorophyllide c + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 49164

8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 8,12-diethyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49168

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