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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,701–21,750 of 31,435, by identifier

7-oxocholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 oxidized [adrenodoxin] + H2O
Left to rightBalance undeterminableRhea 47344
a butanoate ester + H2O = an aliphatic alcohol + butanoate + H(+)
Left to rightBalance undeterminableRhea 47348
a hexanoate ester + H2O = an aliphatic alcohol + hexanoate + H(+)
Direction not assertedBalance undeterminableRhea 47352
an octanoate ester + H2O = an aliphatic alcohol + octanoate + H(+)
Direction not assertedBalance undeterminableRhea 47356
decanoate ester + H2O = decanoate + an aliphatic alcohol + H(+)
Direction not assertedBalance undeterminableRhea 47360
a dodecanoate ester + H2O = an aliphatic alcohol + dodecanoate + H(+)
Direction not assertedBalance undeterminableRhea 47364
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + GDP-alpha-D-mannose = a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP + H(+)

Direction not assertedBalance undeterminableRhea 47368

a quinone + D-glucose = D-glucono-1,5-lactone + a quinol

Direction not assertedBalance undeterminableRhea 47372

(25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 oxidized [adrenodoxin] + 2 H2O

Left to rightBalance undeterminableRhea 47376

(25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 reduced [adrenodoxin] + O2 + H(+) = (25R)-3beta-hydroxycholest-5-en-7-one-26-oate + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 47380

4-acetoxyphenol + H2O = hydroquinone + acetate + H(+)

Direction not assertedBalancedRhea 47384

a tetradecanoate ester + H2O = an aliphatic alcohol + tetradecanoate + H(+)

Direction not assertedBalance undeterminableRhea 47388

hexadecanoate ester + H2O = an aliphatic alcohol + hexadecanoate + H(+)

Left to rightBalance undeterminableRhea 47392

octadecanoate ester + H2O = an aliphatic alcohol + octadecanoate + H(+)

Direction not assertedBalance undeterminableRhea 47396

3-oxo-(9Z-octadecenoyl)-CoA + CoA = (7Z)-hexadecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 47400

(24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) = 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 47404

(24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O = (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA

Direction not assertedBalancedRhea 47408

a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + CoA

Direction not assertedBalance undeterminableRhea 47412

an NDP-alpha-D-glucose + D-glucose = alpha,alpha-trehalose + a ribonucleoside 5'-diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 47416

glutaryl-CoA + A = (2E)-glutaconyl-CoA + AH2

Direction not assertedBalancedRhea 47420

(2E,9Z)-octadecadienoyl-CoA + H2O = (3S)-hydroxy-(9Z-octadecenoyl)-CoA

Left to rightBalancedRhea 47424

(3S)-hydroxy-(9Z-octadecenoyl)-CoA + NAD(+) = 3-oxo-(9Z-octadecenoyl)-CoA + NADH + H(+)

Left to rightBalancedRhea 47428

(7Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47432

(2E,7Z)-hexadecadienoyl-CoA + H2O = (3S)-hydroxy-(7Z-hexadecenoyl)-CoA

Left to rightBalancedRhea 47436

(3S)-hydroxy-(7Z-hexadecenoyl)-CoA + NAD(+) = 3-oxo-(7Z-hexadecenoyl)-CoA + NADH + H(+)

Left to rightBalancedRhea 47440

3-oxo-(7Z-hexadecenoyl)-CoA + CoA = (5Z)-tetradecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 47444

(5Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 47448

(2E,5Z)-tetradecadienoyl-CoA + H2O = (3S)-hydroxy-(5Z-tetradecenoyl)-CoA

Left to rightBalancedRhea 47452

(3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+) = 3-oxo-(5Z-tetradecenoyl)-CoA + NADH + H(+)

Left to rightBalancedRhea 47456

3-oxo-(5Z-tetradecenoyl)-CoA + CoA = (3Z)-dodecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 47460

(3E,5Z)-tetradecadienoyl-CoA = (2E,5Z)-tetradecadienoyl-CoA

ReversibleBalancedRhea 47464

(2E,4E)-tetradecadienoyl-CoA = (3E,5Z)-tetradecadienoyl-CoA

Right to leftBalancedRhea 47468

(2E,4E)-tetradecadienoyl-CoA + NADPH + H(+) = (3E)-tetradecenoyl-CoA + NADP(+)

Left to rightBalancedRhea 47472

(3E)-tetradecenoyl-CoA = (2E)-tetradecenoyl-CoA

Left to rightBalancedRhea 47476

deoxycholate + NADP(+) = 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NADPH + H(+)

Direction not assertedBalancedRhea 47480

deoxycholate + NAD(+) = 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NADH + H(+)

Direction not assertedBalancedRhea 47484

12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NADPH + H(+) = isodeoxycholate + NADP(+)

Direction not assertedBalancedRhea 47488

12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NADH + H(+) = isodeoxycholate + NAD(+)

Direction not assertedBalancedRhea 47492

lithocholate + NADP(+) = 3-oxo-5beta-cholan-24-oate + NADPH + H(+)

Right to leftBalancedRhea 47496

cholate + NADP(+) = 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + NADPH + H(+)

Direction not assertedBalancedRhea 47500

chenodeoxycholate + NADP(+) = 3-oxochenodeoxycholate + NADPH + H(+)

Direction not assertedBalancedRhea 47504

3-oxo-5beta-cholan-24-oate + NADH + H(+) = isolithocholate + NAD(+)

Direction not assertedBalancedRhea 47508

7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + NADH + H(+) = isocholate + NAD(+)

Direction not assertedBalancedRhea 47512

3-oxochenodeoxycholate + NADH + H(+) = isochenodeoxycholate + NAD(+)

Direction not assertedBalancedRhea 47516

3-oxo-5beta-cholan-24-oate + NADPH + H(+) = isolithocholate + NADP(+)

Left to rightBalancedRhea 47520

cholate + NAD(+) = 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + NADH + H(+)

Direction not assertedBalancedRhea 47524

7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + NADPH + H(+) = isocholate + NADP(+)

Direction not assertedBalancedRhea 47528

chenodeoxycholate + NAD(+) = 3-oxochenodeoxycholate + NADH + H(+)

Direction not assertedBalancedRhea 47532

3-oxochenodeoxycholate + NADPH + H(+) = isochenodeoxycholate + NADP(+)

Direction not assertedBalancedRhea 47536

7-oxolithocholate + NADPH + H(+) = ursodeoxycholate + NADP(+)

Left to rightBalancedRhea 47540

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