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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,451–21,500 of 31,435, by identifier

L-threo-3-phenylserine = 3-phenylpyruvate + NH4(+)
Direction not assertedBalancedRhea 46328
a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O
Direction not assertedBalance undeterminableRhea 46332
3-oxochola-4,17-dien-22-oyl-CoA + H2O = 17-hydroxy-3-oxochol-4-en-22-oyl-CoA
Direction not assertedBalancedRhea 46336
N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Left to rightBalancedRhea 46340
propanoyl-CoA + tetradecanoyl-CoA = 3-oxo-2-methylhexadecanoyl-CoA + CoA
Right to leftBalancedRhea 46344
(2E)-octenoyl-CoA + H2O = 3-hydroxyoctanoyl-CoA
Direction not assertedBalancedRhea 46348
(2E)-decenoyl-CoA + H2O = 3-hydroxydecanoyl-CoA

Direction not assertedBalancedRhea 46352

octadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxyoctadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 46356

a 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 46360

an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O

Left to rightBalance undeterminableRhea 46364

a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 46368

(9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 46372

a (9Z)-octadecenoyl-containing glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 46376

7alpha-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (24S)-7alpha-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 46380

(24S)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 24S,25-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 46384

(24S)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (24S,25R)-24,26-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 46388

4beta-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 4beta,24S-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 46392

an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an (11E)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 46396

2 reduced [adrenodoxin] + cholesterol + O2 + 2 H(+) = (25R)-cholest-5-ene-3beta,26-diol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 46400

a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 46404

a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 46408

a (7Z,10Z)-hexadecadienoyl-containing glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a (7Z,10Z,13Z)-hexadecatrienoyl-containing glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 46412

hexadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (6Z)-hexadecenoyl-[ACP] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 46416

(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 46420

(8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Left to rightBalance undeterminableRhea 46424

4beta-hydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-4beta,26-dihydroxycholesterol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 46428

(25R)-4beta,26-dihydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3beta,4beta-dihydroxycholest-5-en-26-al + 2 oxidized [adrenodoxin] + 2 H2O

Left to rightBalance undeterminableRhea 46432

(25R)-3beta,4beta-dihydroxycholest-5-en-26-al + 2 reduced [adrenodoxin] + O2 + H(+) = (25R)-3beta,4beta-dihydroxycholest-5-en-26-oate + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 46436

a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 = a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + A + 2 H2O

Direction not assertedBalance undeterminableRhea 46440

(11Z)-hexadecenoyl-CoA + AH2 + O2 = (10E,12Z)-hexadecadienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 46444

2 L-tyrosyl-tRNA(Tyr) = cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)

Direction not assertedBalancedRhea 46448

2 L-leucyl-tRNA(Leu) = cyclo(L-leucyl-L-leucyl) + 2 tRNA(Leu) + 2 H(+)

Direction not assertedBalancedRhea 46452

5alpha-cholest-8,14-dien-3beta-ol + NADPH + H(+) = 5alpha-cholest-8-en-3beta-ol + NADP(+)

Direction not assertedBalancedRhea 46456

(22R)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (22R,7alpha)-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 46460

(24S)-25-epoxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (24S,25)-epoxy-7alpha-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 46464

an N-(acyl)-sphingosylphosphocholine(in) + ATP + H2O = an N-(acyl)-sphingosylphosphocholine(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 46468

4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 46472

4alpha-hydroxymethylzymosterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formylzymosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 46476

4alpha-formylzymosterol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxyzymosterol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 46480

alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)

Direction not assertedBalancedRhea 46484

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(in) = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(out)

Left to rightBalancedTransportRhea 46488

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine(in) = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine(out)

Left to rightBalancedTransportRhea 46492

N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine(in) = N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine(out)

Left to rightBalancedTransportRhea 46496

UMP + 2-oxoglutarate + O2 = uridine-5'-aldehyde + succinate + CO2 + phosphate

Direction not assertedBalancedRhea 46500

dodecanoyl-AMP + holo-[ACP] = dodecanoyl-[ACP] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 46504

nitrobenzene + NADH + O2 = catechol + nitrite + NAD(+)

Direction not assertedBalancedRhea 46508

an N-(1,2-saturated acyl)sphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-[(2'R)-hydroxyacyl]sphinganine + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 46512

dodecanoyl-[ACP] + FAD + H(+) = (2Z)-dodecenoyl-[ACP] + FADH2

Direction not assertedBalance undeterminableRhea 46516

an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 46520

(11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 46524

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