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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,151–21,200 of 31,435, by identifier

acarbose + ATP = acarbose 7(IV)-phosphate + ADP + H(+)
Direction not assertedBalancedRhea 45124
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoate + H(+)
Left to rightBalancedRhea 45128
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)
Left to rightBalancedRhea 45132
2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate = 7,8-dihydroneopterin 3'-phosphate + H2O
Direction not assertedBalancedRhea 45136
4-carboxy-L-glutamyl-[protein] + 2,3-epoxyphylloquinone + H2O + H(+) = phylloquinol + L-glutamyl-[protein] + CO2 + O2
Right to leftBalance undeterminableRhea 45140
3-(methylsulfanyl)acryloyl-CoA + 2 H2O = methanethiol + acetaldehyde + CO2 + CoA
Direction not assertedBalancedRhea 45144

3-(methylsulfanyl)acryloyl-CoA + H2O = 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA

Direction not assertedBalancedRhea 45148

3-hydroxy-3-(methylsulfanyl)propanoyl-CoA = 3-oxopropanoyl-CoA + methanethiol

Direction not assertedBalancedRhea 45152

3-oxopropanoyl-CoA + H2O = 3-oxopropanoate + CoA + H(+)

Direction not assertedBalancedRhea 45156

3-oxopropanoate + H(+) = acetaldehyde + CO2

Direction not assertedBalancedRhea 45160

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Left to rightBalancedRhea 45164

2 (E)-sinapoyl-CoA + spermidine = N(1),N(8)-bis[(E)-sinapoyl]-spermidine + 2 CoA + 2 H(+)

Direction not assertedBalancedRhea 45168

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 45172

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 45176

2 (E)-4-coumaroyl-CoA + spermidine = N(1),N(8)-bis(coumaroyl)-spermidine + 2 CoA + 2 H(+)

Direction not assertedBalancedRhea 45180

5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + NH4(+) = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + H2O + H(+)

Direction not assertedBalancedRhea 45184

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalance undeterminableRhea 45188

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalance undeterminableRhea 45192

5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)

Direction not assertedBalance undeterminableRhea 45196

methyl-Co(III)-[corrinoid Fe-S protein] + (6S)-5,6,7,8-tetrahydrofolate = Co(I)-[corrinoid Fe-S protein] + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalance undeterminableRhea 45200

Co(I)-[methanol-specific corrinoid protein] + methanol + H(+) = methyl-Co(III)-[methanol-specific corrinoid protein] + H2O

Direction not assertedBalance undeterminableRhea 45204

methyl-Co(III)-[methanol-specific corrinoid protein] + coenzyme M = Co(I)-[methanol-specific corrinoid protein] + methyl-coenzyme M + H(+)

Direction not assertedBalance undeterminableRhea 45208

Co(I)-[corrinoid Fe-S protein] + acetyl-CoA + H(+) = methyl-Co(III)-[corrinoid Fe-S protein] + CO + CoA

Direction not assertedBalance undeterminableRhea 45212

methyl-Co(III)-[dimethylamine-specific corrinoid protein] + coenzyme M = Co(I)-[dimethylamine-specific corrinoid protein] + methyl-coenzyme M + H(+)

Direction not assertedBalance undeterminableRhea 45216

methyl-Co(III)-[trimethylamine-specific corrinoid protein] + coenzyme M = Co(I)-[trimethylamine-specific corrinoid protein] + methyl-coenzyme M + H(+)

Direction not assertedBalance undeterminableRhea 45220

(3E,5Z,8Z,11Z,14Z)-eicosapentaenoyl-CoA = (2E,4E,8Z,11Z,14Z)-eicosapentaenoyl-CoA

Left to rightBalancedRhea 45224

a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA

Left to rightBalance undeterminableRhea 45228

a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(2E)-enoyl-CoA + NADP(+)

Direction not assertedBalance undeterminableRhea 45232

(25R)-3beta-hydroxy-5-cholesten-26-al + 2 reduced [adrenodoxin] + O2 + H(+) = (25R)-3beta-hydroxy-5-cholestenoate + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 45236

a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA

Left to rightBalance undeterminableRhea 45240

(3E,5Z)-octadienoyl-CoA = (2E,4E)-octadienoyl-CoA

Left to rightBalancedRhea 45244

butanoate(out) = butanoate(in)

Direction not assertedBalancedTransportRhea 45248

tetradecanoate(out) = tetradecanoate(in)

Direction not assertedBalancedTransportRhea 45252

hexadecanoate(out) = hexadecanoate(in)

Direction not assertedBalancedTransportRhea 45256

tetracosanoate(out) = tetracosanoate(in)

Direction not assertedBalancedTransportRhea 45260

(9Z,12Z)-octadecadienoate(out) = (9Z,12Z)-octadecadienoate(in)

Direction not assertedBalancedTransportRhea 45264

4'-hydroxyechinenone + AH2 + O2 = 4',4'-dihydroxyechinenone + A + H2O

Direction not assertedBalancedRhea 45268

12-phosphooxy-(9Z)-octadecenoate + H2O = 12-hydroxy-(9Z)-octadecenoate + phosphate

Left to rightBalancedRhea 45272

12-phosphooxy-(9E)-octadecenoate + H2O = 12-hydroxy-(9E)-octadecenoate + phosphate

Left to rightBalancedRhea 45276

12-(phosphooxy)octadecanoate + H2O = 12-hydroxyoctadecanoate + phosphate

Left to rightBalancedRhea 45280

eicosanoyl-CoA + sphing-4-enine = N-eicosanoyl-sphing-4-enine + CoA + H(+)

Left to rightBalancedRhea 45284

2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2

Left to rightBalancedRhea 45288

2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O

Left to rightBalancedRhea 45292

a sphingosylphosphocholine + H2O = a sphingoid base + phosphocholine + H(+)

Left to rightBalance undeterminableRhea 45296

an N-(acyl)-sphingosylphosphocholine + H2O = an N-acyl-sphingoid base + phosphocholine + H(+)

Left to rightBalance undeterminableRhea 45300

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphocholine + H(+)

Left to rightBalancedRhea 45304

prostaglandin D2-ethanolamide + NADPH + H(+) = 11beta-prostaglandin F2-ethanolamide + NADP(+)

Left to rightBalancedRhea 45308

prostaglandin F2alpha + NADP(+) = prostaglandin H2 + NADPH + H(+)

Right to leftBalancedRhea 45312

prostaglandin D2 + NADPH + H(+) = 11beta-prostaglandin F2 + NADP(+)

Left to rightBalancedRhea 45316

N-(15Z-tetracosenoyl)sphing-4-enine-1-phosphocholine + H2O = N-(15Z-tetracosenoyl)-sphing-4-enine + phosphocholine + H(+)

Left to rightBalancedRhea 45320

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