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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

21,101–21,150 of 31,435, by identifier

2-oxoadipate + acetyl-CoA + H2O = (R)-dihomocitrate + CoA + H(+)
Direction not assertedBalancedRhea 44924
2-oxoheptanedioate + acetyl-CoA + H2O = (R)-trihomocitrate + CoA + H(+)
Direction not assertedBalancedRhea 44928
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate
Left to rightBalancedRhea 44932
(9Z,12Z,15Z)-octadecatrienoate + ATP + CoA = (9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate
Left to rightBalancedRhea 44936
1-O-alkyl-2,3-diacyl-sn-glycerol + H2O = 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+)
Direction not assertedBalance undeterminableRhea 44940
1-O-alkyl-3-acyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + a fatty acid + H(+)
Direction not assertedBalance undeterminableRhea 44944
1-O-alkyl-2,3-diacyl-sn-glycerol + H2O = 1-O-alkyl-2-acyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 44948

(2E)-octenoyl-CoA + NADPH + H(+) = octanoyl-CoA + NADP(+)

Left to rightBalancedRhea 44952

(2E)-hexenoyl-CoA + NADPH + H(+) = hexanoyl-CoA + NADP(+)

Left to rightBalancedRhea 44956

(2E)-decenoyl-CoA + NADPH + H(+) = decanoyl-CoA + NADP(+)

Left to rightBalancedRhea 44960

(2E)-dodecenoyl-CoA + NADPH + H(+) = dodecanoyl-CoA + NADP(+)

Left to rightBalancedRhea 44964

(2E)-tetradecenoyl-CoA + NADPH + H(+) = tetradecanoyl-CoA + NADP(+)

Left to rightBalancedRhea 44968

hexanoyl-CoA + (R)-carnitine = O-hexanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44972

propanoyl-CoA + (R)-carnitine = O-propanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44976

butanoyl-CoA + (R)-carnitine = O-butanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44980

3-methylbutanoyl-CoA + (R)-carnitine = O-3-methylbutanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44984

2-methylpropanoyl-CoA + (R)-carnitine = O-isobutanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44988

2-methylbutanoyl-CoA + (R)-carnitine = O-2-methylbutanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44992

acetoacetyl-CoA + (R)-carnitine = O-3-oxobutanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 44996

3-hydroxybutanoyl-CoA + (R)-carnitine = O-3-hydroxybutanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 45000

2,6-dimethylheptanoyl-CoA + (R)-carnitine = O-2,6-dimethylheptanoyl-(R)-carnitine + CoA

Left to rightBalancedRhea 45004

N-(octadecanoyl)-sphinganine + H2O = sphinganine + octadecanoate

Left to rightBalancedRhea 45008

N-octadecanoyl-(4R)-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + octadecanoate

Direction not assertedBalancedRhea 45012

L-selenohomocysteine + 5-methyltetrahydropteroyltri-L-glutamate = tetrahydropteroyltri-L-glutamate + L-selenomethionine

Direction not assertedBalancedRhea 45016

L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 45020

cholesterol + NADPH + O2 + H(+) = 7-dehydrocholesterol + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 45024

(2S)-methylsuccinyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylfumaryl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 45028

hydroxylamine + 4 Fe(III)-[cytochrome c] + H2O = 4 Fe(II)-[cytochrome c] + nitrite + 5 H(+)

Direction not assertedBalance undeterminableRhea 45032

hydroxylamine + 3 Fe(III)-[cytochrome c] = nitric oxide + 3 Fe(II)-[cytochrome c] + 3 H(+)

Direction not assertedBalance undeterminableRhea 45036

hydroxylamine + 2 Fe(III)-[cytochrome c] = nitroxyl + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 45040

nitroxyl + 2 Fe(II)-[cytochrome c] + O2 + H(+) = 2 Fe(III)-[cytochrome c] + nitrite + H2O

Direction not assertedBalance undeterminableRhea 45044

acetamide + H2O = acetate + NH4(+)

Direction not assertedBalancedRhea 45048

(2E)-butenoyl-CoA + (R)-carnitine = O-(2E)-butenoyl-(R)-carnitine + CoA

Direction not assertedBalancedRhea 45052

deoxynogalonate + O2 = nogalonate + H2O + H(+)

Direction not assertedBalancedRhea 45056

N-(9Z-octadecenoyl) ethanolamine + H2O = ethanolamine + (9Z)-octadecenoate

Left to rightBalancedRhea 45060

N-hexadecanoylethanolamine + H2O = ethanolamine + hexadecanoate

Left to rightBalancedRhea 45064

(R)-carnitine + an acyl-CoA = an O-acyl-(R)-carnitine + CoA

Direction not assertedBalance undeterminableRhea 45068

(9Z)-octadecenoyl-CoA + reduced [NADPH--hemoprotein reductase] + O2 = (9Z)-18-hydroxyoctadecenoyl-CoA + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 45072

(9Z,12Z)-octadecadienoyl-CoA + reduced [NADPH--hemoprotein reductase] + O2 = (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 45076

3-[[[(2R,3R)-3-carboxyoxiran-2-yl]carbonyl]amino]-L-alanine + L-valine + ATP = dapdiamide E + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 45080

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 7-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 45084

a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline

Left to rightBalance undeterminableRhea 45088

N-octanoylsphing-4-enine + H2O = octanoate + sphing-4-enine

Left to rightBalancedRhea 45092

(9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 45096

6-demethylmitomycin B + S-adenosyl-L-methionine = mitomycin B + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 45100

6-demethylmitomycin A + S-adenosyl-L-methionine = mitomycin A + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 45104

(+)-alpha-tocopherol + reduced [NADPH--hemoprotein reductase] + O2 = 13-hydroxy-alpha-tocopherol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 45108

gamma-tocopherol + NADPH + O2 + H(+) = 13-hydroxy-gamma-tocopherol + NADP(+) + H2O

Left to rightBalancedRhea 45112

(4R)-ipsdienol + NADP(+) = ipsdienone + NADPH + H(+)

Direction not assertedBalancedRhea 45116

(4R)-ipsdienol + NAD(+) = ipsdienone + NADH + H(+)

Direction not assertedBalancedRhea 45120

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