Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

18,751–18,800 of 31,435, by identifier

2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) = (beta-L-Ara4N)2-(Kdo)2-lipid A + 2 di-trans,octa-cis-undecaprenyl phosphate
Direction not assertedBalancedRhea 35371
(beta-L-Ara4N)2-(Kdo)2-lipid A(in) + ATP + H2O = (beta-L-Ara4N)2-(Kdo)2-lipid A(out) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 35375
(6Z,9Z,12Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z)-eicosatrienoyl-CoA + CO2 + CoA
Left to rightBalancedRhea 35379
precorrin-6B + S-adenosyl-L-methionine = precorrin-7 + S-adenosyl-L-homocysteine + CO2 + H(+)
Direction not assertedBalancedRhea 35383
precorrin-7 + S-adenosyl-L-methionine = precorrin-8X + S-adenosyl-L-homocysteine + 2 H(+)
Direction not assertedBalancedRhea 35387
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + CO2 + CoA
Left to right

→

Balanced

Rhea 35391

cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine + 1-O-[(E)-4-coumaroyl]-beta-D-glucose = cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside] + beta-D-glucose + H(+)

Direction not assertedBalancedRhea 35399

(3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol + NADP(+) = (3R)-vestitone + NADPH + H(+)

Direction not assertedBalancedRhea 35403

medicarpin + H2O = 4'-methoxyisoflavan-2',4,7-triol

Direction not assertedBalancedRhea 35407

an anthocyanidin 3-O-beta-D-glucoside + (E)-4-coumaroyl-CoA = an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 35411

an anthocyanidin 3-O-beta-D-sambubioside + UDP-alpha-D-glucose = an anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + UDP + H(+)

Direction not assertedBalance undeterminableRhea 35415

an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = an anthocyanidin 3-O-sophoroside + UDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 35419

an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = an anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 35423

cyanidin 3-O-beta-D-glucoside + 1-O-(trans-sinapoyl)-beta-D-glucose = cyanidin 3,5-di-O-beta-D-glucoside + (E)-sinapate

Direction not assertedBalancedRhea 35427

1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + cyanidin 3-O-beta-D-glucoside = cyanidin 3,7-di-O-beta-D-glucoside + vanillate

Direction not assertedBalancedRhea 35431

cyanidin 3-O-beta-D-galactoside + UDP-alpha-D-xylose = cyanidin 3-O-[beta-D-xylosyl-(1->2)-beta-D-galactoside] + UDP + H(+)

Direction not assertedBalancedRhea 35435

CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + L-serine = archaetidylserine + CMP + H(+)

Direction not assertedBalancedRhea 35439

an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-xylose = an anthocyanidin 3-O-beta-D-sambubioside + UDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 35443

(1'S)-averantin + NADP(+) = norsolorinic acid + NADPH + H(+)

Direction not assertedBalancedRhea 35447

5alpha-cholest-7-en-3-one + 3 NADPH + 3 O2 + 2 H(+) = (25S)-Delta7-dafachronate + 3 NADP(+) + 4 H2O

Direction not assertedBalancedRhea 35455

cholesterol + NAD(+) = cholest-5-en-3-one + NADH + H(+)

Direction not assertedBalancedRhea 35459

lathosterol + NAD(+) = 5alpha-cholest-7-en-3-one + NADH + H(+)

Direction not assertedBalancedRhea 35463

S,S-dimethyl-beta-propiothetin + (6S)-5,6,7,8-tetrahydrofolate = 3-(methylsulfanyl)propanoate + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalancedRhea 35467

(+)-6a-hydroxymaackiain + S-adenosyl-L-methionine = (+)-pisatin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 35471

(1'S,5'S)-5'-hydroxyaverantin + NAD(+) = (S)-5'-oxoaverantin + NADH + H(+)

Direction not assertedBalancedRhea 35475

(1'S,5'R)-5'-hydroxyaverantin + NAD(+) = (S)-5'-oxoaverantin + NADH + 2 H(+)

Direction not assertedBalancedRhea 35479

5alpha-cholest-7-en-3-one + S-adenosyl-L-methionine = 4alpha-methyl-5alpha-cholest-7-en-3-one + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 35483

(2S)-naringenin + reduced [NADPH--hemoprotein reductase] + O2 = 2-hydroxy-2,3-dihydrogenistein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 35487

N-(4-aminobenzoyl)-L-glutamate + H2O = 4-aminobenzoate + L-glutamate

Direction not assertedBalancedRhea 35495

11-oxo-beta-amyrin + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = glycyrrhetinate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 35499

11-oxo-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 30-hydroxy-11-oxo-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 35503

30-hydroxy-11-oxo-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = glycyrrhetaldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 35507

glycyrrhetaldehyde + reduced [NADPH--hemoprotein reductase] + O2 = glycyrrhetinate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 35511

4'''-demalonylsalvianin + malonyl-CoA = salvianin + CoA

Direction not assertedBalancedRhea 35515

(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl) ethanolamine + H2O = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ethanolamine

Direction not assertedBalancedRhea 35519

N-ethylmaleimide + NADPH + H(+) = N-ethylsuccinimide + NADP(+)

Direction not assertedBalancedRhea 35523

N-ethylmaleimide + NADH + H(+) = N-ethylsuccinimide + NAD(+)

Direction not assertedBalancedRhea 35527

cyclo(L-phenylalanyl-L-leucyl) + 2 O2 = albonoursin + 2 H2O2

Direction not assertedBalancedRhea 35531

cyclo(L-phenylalanyl-L-leucyl) + O2 = cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2

Direction not assertedBalancedRhea 35535

cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 = albonoursin + H2O2

Direction not assertedBalancedRhea 35539

3-phosphooxypyruvate + H2O = 3-hydroxypyruvate + phosphate

Direction not assertedBalancedRhea 35543

cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 35547

cyclo(L-leucyl-L-leucyl) + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 4 H(+) = pulcherriminic acid + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 35555

menaquinone-7 + NADH + H(+) = menaquinol-7 + NAD(+)

Direction not assertedBalancedRhea 35559

N-(9Z-hexadecenoyl) ethanolamine + H2O = (9Z)-hexadecenoate + ethanolamine

Left to rightBalancedRhea 35563

N-(9Z,12Z-octadecadienoyl)-ethanolamine + H2O = ethanolamine + (9Z,12Z)-octadecadienoate

Direction not assertedBalancedRhea 35567

(1'S)-averantin + reduced [NADPH--hemoprotein reductase] + O2 = (1'S,5'S)-5'-hydroxyaverantin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 35571

(1'S)-averantin + reduced [NADPH--hemoprotein reductase] + O2 = (1'S,5'R)-5'-hydroxyaverantin + oxidized [NADPH--hemoprotein reductase] + H2O

Direction not assertedBalance undeterminableRhea 35575

anthocyanin A8 + 1-O-(trans-sinapoyl)-beta-D-glucose = anthocyanin A11 + D-glucose

Direction not assertedBalancedRhea 35579

2-dehydro-3-deoxy-D-gluconate = D-glyceraldehyde + pyruvate

Direction not assertedBalancedRhea 35583

Page 376 of 629