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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

18,501–18,550 of 31,435, by identifier

2 reduced [adrenodoxin] + cholesterol + O2 + 2 H(+) = (22R)-hydroxycholesterol + 2 oxidized [adrenodoxin] + H2O
Left to rightBalance undeterminableRhea 34335
(22R)-hydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (20R,22R)-20,22-dihydroxycholesterol + 2 oxidized [adrenodoxin] + H2O
Left to rightBalance undeterminableRhea 34339
(20R,22R)-20,22-dihydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 4-methylpentanal + pregnenolone + 2 oxidized [adrenodoxin] + 2 H2O
Left to rightBalance undeterminableRhea 34343
(2E)-geraniol + NAD(+) = (2E)-geranial + NADH + H(+)
Direction not assertedBalancedRhea 34347
(2E)-geranial + NAD(+) + H2O = geranate + NADH + 2 H(+)
Direction not assertedBalancedRhea 34351
a 1,2-diacylglycerol + H2O = a 2-acylglycerol + a carboxylate + H(+)
Direction not assertedBalance undeterminableRhea 34359

N-acetyl-alpha-D-galactosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-galactosamine + diphosphate

Left to rightBalancedRhea 34363

acrylamide + H2O = acrylate + NH4(+)

Direction not assertedBalancedRhea 34367

indole-3-acetamide + H2O = (indol-3-yl)acetate + NH4(+)

Direction not assertedBalancedRhea 34371

4-guanidinobutanamide + H2O = 4-guanidinobutanoate + NH4(+)

Direction not assertedBalancedRhea 34375

alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP + 2 H(+)

Direction not assertedBalancedRhea 34379

alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP + H(+)

Direction not assertedBalancedRhea 34383

beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP + H(+)

Direction not assertedBalancedRhea 34387

beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose = [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP + 28 H(+)

Direction not assertedBalancedRhea 34391

L-phenylalanine = (3R)-beta-phenylalanine

Direction not assertedBalancedRhea 34395

9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone

Direction not assertedBalancedRhea 34399

9-cis-10'-apo-beta-carotenal + 2 O2 = (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactone

Direction not assertedBalancedRhea 34403

3 ATP = 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 diphosphate

Left to rightBalancedRhea 34407

cannabigerolate + O2 = cannabidiolate + H2O2

Direction not assertedBalancedRhea 34411

(1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 34415

(+)-lariciresinol + NADP(+) = (+)-pinoresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34419

(-)-secoisolariciresinol + NADP(+) = (+)-lariciresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34423

(-)-lariciresinol + NADP(+) = (-)-pinoresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34427

(+)-secoisolariciresinol + NADP(+) = (-)-lariciresinol + NADPH + H(+)

Direction not assertedBalancedRhea 34431

4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 34435

dTDP-4-amino-4,6-dideoxy-alpha-D-galactose + acetyl-CoA = dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + CoA + H(+)

Direction not assertedBalancedRhea 34443

dTDP-6-deoxy-beta-L-talose + NAD(+) = dTDP-4-dehydro-beta-L-rhamnose + NADH + H(+)

Direction not assertedBalancedRhea 34447

dTDP-6-deoxy-beta-L-talose = dTDP-beta-L-rhamnose

Direction not assertedBalancedRhea 34451

all-trans-beta-carotene = 9-cis-beta-carotene

Direction not assertedBalancedRhea 34455

8-hydroxycopalyl diphosphate + H2O = sclareol + diphosphate

Direction not assertedBalancedRhea 34459

8-hydroxycopalyl diphosphate = cis-abienol + diphosphate

Direction not assertedBalancedRhea 34463

(2E,6E)-farnesyl diphosphate = valerena-4,7(11)-diene + diphosphate

Direction not assertedBalancedRhea 34467

propanoyl-CoA + NAD(+) = acryloyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 34471

2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate

Direction not assertedBalancedRhea 34475

(1R,2R,3R)-prephytoene diphosphate = 15-cis-phytoene + diphosphate

Direction not assertedBalancedRhea 34479

4-coumaroyl-CoA + malonyl-CoA + H2O + H(+) = 4-hydroxybenzalacetone + 2 CO2 + 2 CoA

Direction not assertedBalancedRhea 34483

N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol + dTDP-beta-L-rhamnose = alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + dTDP + H(+)

Direction not assertedBalancedRhea 34487

UDP-N,N'-diacetylbacillosamine + H2O = 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H(+)

Direction not assertedBalancedRhea 34491

(9Z,12Z,15Z)-octadecatrienoate + O2 = (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 34495

1-deoxypentalenate + reduced 2[4Fe-4S]-[ferredoxin] + O2 + 2 H(+) = pentalenate + oxidized 2[4Fe-4S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 34499

(2E,6E)-farnesyl diphosphate + H2O = (+)-epi-alpha-bisabolol + diphosphate

Direction not assertedBalancedRhea 34503

2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + phosphoenolpyruvate + H2O = N,N-diacetyllegionaminate + phosphate

Direction not assertedBalancedRhea 34507

N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 34511

tri-trans,hepta-cis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine = N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UMP

Direction not assertedBalancedRhea 34515

N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + 3 UDP-N-acetyl-alpha-D-galactosamine = [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + 3 UDP + 3 H(+)

Direction not assertedBalancedRhea 34519

[alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose = [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP + H(+)

Direction not assertedBalancedRhea 34523

L-phenylalanine = (S)-3-amino-3-phenylpropanoate

Direction not assertedBalancedRhea 34527

dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + acetyl-CoA = dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + CoA + H(+)

Direction not assertedBalancedRhea 34531

hexadecanoyl-CoA + L-alanine + H(+) = 1-deoxy-3-dehydrosphinganine + CO2 + CoA

Direction not assertedBalancedRhea 34535

tellurite + S-adenosyl-L-methionine = methanetellurite + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 34539

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