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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,951–18,000 of 31,435, by identifier

P(1),P(5)-bis(5'-adenosyl) pentaphosphate + H2O = adenosine 5'-tetraphosphate + AMP + 2 H(+)
Left to rightBalancedRhea 32051
(2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + H2O = (R)-glycerate + D-glucose
Direction not assertedBalancedRhea 32059
8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate + H(+)
Left to rightBalancedRhea 32063
8-oxoguanine + H2O + H(+) = urate + NH4(+)
Direction not assertedBalancedRhea 32067
geranylgeranyl diphosphate = (13E)-labda-7,13-dien-15-yl diphosphate
Direction not assertedBalancedRhea 32071
geranylgeranyl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate
Direction not assertedBalancedRhea 32075
(13E)-labda-7,13-dien-15-yl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate

Direction not assertedBalancedRhea 32079

pseudaminate + CTP = CMP-pseudaminate + diphosphate

Direction not assertedBalancedRhea 32083

[4)-beta-D-GlcA-(1->4)-2-O-Ac-beta-D-GlcA-(1->4)-beta-D-Glc-(1->4)-[3-O-(CH3CH(OH)CH2C(O))-(R)-4,6-CH3(COO(-))C-beta-D-Gal-(1->3)-beta-D-Glc-(1->4)-beta-D-Glc-(1->4)-beta-D-Glc-(1->6)]-2-O-Ac-alpha-DGlc-(1->](n) + n phosphoenolpyruvate = [4)-beta-D-GlcA-(1->4)-2-O-Ac-beta-D-GlcA-(1->4)-beta-D-Glc-(1->4)-[3-O-(CH3CH(OH)CH2C(O))-(R)-4,6-CH3(COO(-))C-beta-D-Gal-(1->3)-(S)-4,6-CH3(COO(-))C-beta-D-Glc-(1->4)-beta-D-Glc-(1->4)-beta-D-Glc-(1->6)]-2-O-Ac-alpha-DGlc-(1->](n) + n phosphate

Direction not assertedBalance undeterminableRhea 32087

3-O-alpha-L-mycarosylerythronolide B + dTDP-alpha-D-desosamine = erythromycin D + dTDP + H(+)

Direction not assertedBalancedRhea 32091

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + acetyl-CoA = dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + CoA + H(+)

Direction not assertedBalancedRhea 32095

TRIBOA beta-D-glucoside + S-adenosyl-L-methionine = DIMBOA beta-D-glucoside + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32099

trans-resveratrol + 2 S-adenosyl-L-methionine = pterostilbene + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 32103

3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-methionine = pterostilbene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32107

trans-resveratrol + S-adenosyl-L-methionine = 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32111

DIBOA beta-D-glucoside + 2-oxoglutarate + O2 = TRIBOA beta-D-glucoside + succinate + CO2

Direction not assertedBalancedRhea 32115

validamine 7-phosphate + GDP-valienol = validoxylamine A 7'-phosphate + GDP + H(+)

Direction not assertedBalancedRhea 32119

citrate(in) + H(+)(in) = citrate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 32123

L-proline + 2-oxoglutarate + O2 = cis-4-hydroxy-L-proline + succinate + CO2

Direction not assertedBalancedRhea 32127

(2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2

Left to rightBalancedRhea 32131

2-oxobutanoate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA = propanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 32135

malonate + ATP + CoA = malonyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 32139

L-arginine(in) = L-arginine(out)

Direction not assertedBalancedTransportRhea 32143

L-sepiapterin + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+)

Direction not assertedBalancedRhea 32147

9alpha-copalyl diphosphate = (12E)-9alpha-labda-8(17),12,14-triene + diphosphate

Direction not assertedBalancedRhea 32151

7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = epoxyqueuosine(34) in tRNA + adenine + L-methionine + 2 H(+)

Direction not assertedBalancedRhea 32155

epoxyqueuosine(34) in tRNA + AH2 = queuosine(34) in tRNA + A + H2O

Direction not assertedBalancedRhea 32159

N(6)-acetyl-N(6)-hydroxy-L-lysine + citrate + ATP = N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 32163

N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine + N(6)-acetyl-N(6)-hydroxy-L-lysine + ATP = aerobactin + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 32167

phenylacetyl-CoA + NADPH + O2 + H(+) = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP(+) + H2O

Direction not assertedBalancedRhea 32171

a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E)) + GDP-beta-L-fucose = alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + GDP + H(+)

Left to rightBalance undeterminableRhea 32175

(S)-2,3-dihydrodipicolinate + NAD(+) = dipicolinate + NADH + H(+)

Direction not assertedBalancedRhea 32179

cholesterol + O2 = cholest-5-en-3-one + H2O2

Direction not assertedBalancedRhea 32183

cholest-5-en-3-one = cholest-4-en-3-one

Direction not assertedBalancedRhea 32187

2 oxidized [2Fe-2S]-[ferredoxin] + L-glutamate + H2O = 2 reduced [2Fe-2S]-[ferredoxin] + 2-oxoglutarate + NH4(+) + 2 H(+)

Direction not assertedBalance undeterminableRhea 32191

abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O

Direction not assertedBalancedRhea 32195

androsta-1,4-diene-3,17-dione + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 32199

(R)-synephrine = (4-hydroxyphenyl)acetaldehyde + methylamine

Direction not assertedBalancedRhea 32203

(2E,4Z)-2-hydroxyhexa-2,4-dienedioate = (3Z)-2-oxohex-3-enedioate

Direction not assertedBalancedRhea 32207

(Z)-5-oxohex-2-enedioate = (2E,4Z)-2-hydroxyhexa-2,4-dienedioate

Direction not assertedBalancedRhea 32211

(6R)-NADHX = (6S)-NADHX

Direction not assertedBalancedRhea 32215

all-trans-lycopene = gamma-carotene

Direction not assertedBalancedRhea 32219

(6S)-NADHX + ADP = AMP + phosphate + NADH + H(+)

Direction not assertedBalancedRhea 32223

(6R)-NADPHX = (6S)-NADPHX

Direction not assertedBalancedRhea 32227

(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 32231

(6S)-NADPHX + ADP = AMP + phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 32235

gamma-carotene = all-trans-beta-carotene

Direction not assertedBalancedRhea 32239

alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate

Direction not assertedBalancedRhea 32243

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) = (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H(+)

Direction not assertedBalancedRhea 32247

(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NAD(+) = (6R)-L-erythro-6,7-dihydrobiopterin + NADH + H(+)

Direction not assertedBalancedRhea 32251

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