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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,851–17,900 of 31,435, by identifier

beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O = beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + 5-dehydro-4-deoxy-D-glucuronate
Direction not assertedBalancedRhea 31635
mycinamicin III + S-adenosyl-L-methionine = mycinamicin IV + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 31639
mycinamicin VI + S-adenosyl-L-methionine = mycinamicin III + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 31643
beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = N-acetyl-beta-D-galactosamine 6-sulfate + 5-dehydro-4-deoxy-D-glucuronate
Direction not assertedBalancedRhea 31647
beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine
Direction not assertedBalancedRhea 31651
4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate + N-acetyl-beta-D-galactosamine
Direction not asserted

?

Balanced

Rhea 31655

beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine

Direction not assertedBalancedRhea 31659

UDP-N-acetylbacillosamine + 2-oxoglutarate = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + L-glutamate

Direction not assertedBalancedRhea 31663

dTDP-3-amino-3,6-dideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-3-dehydro-6-deoxy-alpha-D-glucose + L-glutamate

Direction not assertedBalancedRhea 31667

dTDP-3-amino-3,6-dideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-mycaminose + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 31671

raucaffrinoline + NADP(+) = perakine + NADPH + H(+)

Direction not assertedBalancedRhea 31675

prosolanapyrone II + O2 = prosolanapyrone III + H2O2

Direction not assertedBalancedRhea 31679

prosolanapyrone III = (-)-solanapyrone A

Direction not assertedBalancedRhea 31683

(9Z,12Z,15Z)-octadecatrienoate + O2 = (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate

Direction not assertedBalancedRhea 31687

(9Z,12Z)-octadecadienoate + O2 = (9R)-hydroperoxy-(10E,12Z)-octadecadienoate

Direction not assertedBalancedRhea 31691

(9Z,12Z)-octadecadienoate + O2 = (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate

Direction not assertedBalancedRhea 31695

pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = pentalen-13-al + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 31699

pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pentalen-13-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 31703

pentalen-13-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pentalen-13-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 31707

beta-amyrin + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 11-oxo-beta-amyrin + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 31711

beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 11alpha-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31715

11alpha-hydroxy-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 11-oxo-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 31719

(2S)-liquiritigenin + reduced [NADPH--hemoprotein reductase] + O2 = (2R,3S)-2,4',7-trihydroxyisoflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 31723

styrene + FADH2 + O2 = (S)-styrene oxide + FAD + H2O + H(+)

Direction not assertedBalancedRhea 31727

3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O + H(+)

Direction not assertedBalancedRhea 31731

3-oxocholan-24-oyl-CoA + NAD(+) = 3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 31735

a 4'-hydroxyisoflavone + S-adenosyl-L-methionine = a 4'-methoxyisoflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 31739

a 4'-hydroxyflavanone + S-adenosyl-L-methionine = a 4'-methoxyflavanone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 31743

3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP(+) + H2O = 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H(+)

Direction not assertedBalancedRhea 31747

chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 7(1)-hydroxychlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 31751

2-oxepin-2(3H)-ylideneacetyl-CoA + H2O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde

Direction not assertedBalancedRhea 31755

dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-desosamine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 31759

a 2-oxocarboxylate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid

Direction not assertedBalance undeterminableRhea 31763

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate = UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate

Direction not assertedBalancedRhea 31767

an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 31771

all-trans-retinyl hexadecanoate + H2O = 11-cis-retinol + hexadecanoate + H(+)

Direction not assertedBalancedRhea 31775

an all-trans-retinyl ester + H2O = 13-cis-retinol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 31779

tuberculosinyl diphosphate + H2O = tuberculosinol + diphosphate

Direction not assertedBalancedRhea 31783

tuberculosinyl diphosphate + H2O = (13R)-edaxadiene + diphosphate

Direction not assertedBalancedRhea 31787

tuberculosinyl diphosphate + H2O = (13S)-edaxadiene + diphosphate

Direction not assertedBalancedRhea 31791

(+)-(E)-beta-caryophyllene + H2O = (+)-caryolan-1-ol

Direction not assertedBalancedRhea 31795

4-amino-5-aminomethyl-2-methylpyrimidine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)

Direction not assertedBalancedRhea 31799

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H2O = 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + UDP + H(+)

Direction not assertedBalancedRhea 31803

(2E,6E)-farnesyl diphosphate = alpha-guaiene + diphosphate

Direction not assertedBalancedRhea 31807

(2E,6E)-farnesyl diphosphate = viridiflorene + diphosphate

Direction not assertedBalancedRhea 31811

(2E,6E)-farnesyl diphosphate = (+)-(E)-beta-caryophyllene + diphosphate

Direction not assertedBalancedRhea 31815

(2E,6E)-farnesyl diphosphate = 5-epi-alpha-selinene + diphosphate

Direction not assertedBalancedRhea 31819

(2E,6E)-farnesyl diphosphate + H2O = cubebol + diphosphate

Direction not assertedBalancedRhea 31823

(2E,6E)-farnesyl diphosphate = (+)-gamma-cadinene + diphosphate

Direction not assertedBalancedRhea 31827

(2E,6E)-farnesyl diphosphate = delta-guaiene + diphosphate

Direction not assertedBalancedRhea 31831

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