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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

17,751–17,800 of 31,435, by identifier

di-trans,octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans,octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H(+)
Direction not assertedBalancedRhea 31227
4-acetamidobutanal + NAD(+) + H2O = 4-acetamidobutanoate + NADH + 2 H(+)
Direction not assertedBalancedRhea 31231
(4S)-4-hydroxy-L-glutamate + 2-oxoglutarate = (4R)-4-hydroxy-2-oxoglutarate + L-glutamate
Direction not assertedBalancedRhea 31235
uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2
Left to rightBalancedRhea 31239
L-4-hydroxyglutamate semialdehyde + NAD(+) + H2O = (4S)-4-hydroxy-L-glutamate + NADH + 2 H(+)
Direction not assertedBalancedRhea 31243
prop-2-ynal + pyrroloquinoline quinol + H(+) = prop-2-yn-1-ol + pyrroloquinoline quinone
Direction not asserted

?

Balanced

Rhea 31247

(S)-3-hydroxyisobutanoyl-CoA + H2O = (S)-3-hydroxy-2-methylpropanoate + CoA + H(+)

Direction not assertedBalancedRhea 31251

(2S)-2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate

Direction not assertedBalancedRhea 31255

but-3-ynal + NAD(+) + H2O = 3-butynoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31259

but-3-ynal + pyrroloquinoline quinol + H(+) = but-3-yn-1-ol + pyrroloquinoline quinone

Direction not assertedBalancedRhea 31263

6-hydroxyhexanoate + NADP(+) = 6-oxohexanoate + NADPH + H(+)

Direction not assertedBalancedRhea 31267

1-hydroxy-2-naphthoate + NADH + O2 + 2 H(+) = naphthalene-1,2-diol + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 31271

(S)-3-hydroxy-2-methylpropanoate + NAD(+) = (S)-2-methyl-3-oxopropanoate + NADH + H(+)

Direction not assertedBalancedRhea 31275

isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = (2Z,6E,10E)-geranylgeranyl diphosphate + diphosphate

Direction not assertedBalancedRhea 31279

sn-glycerol 3-phosphate + FAD + H(+) = dihydroxyacetone phosphate + FADH2

Direction not assertedBalancedRhea 31283

propanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = acryloyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 31287

(2E)-2-hydroxypenta-2,4-dienoate = 2-oxopent-4-enoate

Direction not assertedBalancedRhea 31295

perillyl aldehyde + NAD(+) + H2O = perillate + NADH + 2 H(+)

Direction not assertedBalancedRhea 31299

a reduced flavin + NAD(+) = an oxidized flavin + NADH + 2 H(+)

Direction not assertedBalance undeterminableRhea 31303

an alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)

Left to rightBalance undeterminableRhea 31307

ADP-alpha-D-glucose + (2R)-3-phosphoglycerate = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+)

Direction not assertedBalancedRhea 31311

GDP-D-glucose + (2R)-3-phosphoglycerate = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)

Direction not assertedBalancedRhea 31315

(2R)-3-phosphoglycerate + UDP-alpha-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + UDP + H(+)

Direction not assertedBalancedRhea 31319

(2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP-alpha-D-mannose = (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + GDP + H(+)

Direction not assertedBalancedRhea 31323

CDP-1L-myo-inositol + 1D-myo-inositol 3-phosphate = bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate + CMP + H(+)

Direction not assertedBalancedRhea 31327

molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate

Left to rightBalancedRhea 31331

Mo-molybdopterin + CTP + H(+) = Mo-molybdopterin cytosine dinucleotide + diphosphate

Direction not assertedBalancedRhea 31335

holo-[ACP] + acetate + ATP = acetyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 31339

(2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + H2O = (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate

Direction not assertedBalancedRhea 31343

(+)-abscisic acid D-glucopyranosyl ester + H2O = 2-cis-(+)-abscisate + beta-D-glucose + H(+)

Direction not assertedBalancedRhea 31347

lupan-3beta,20-diol = (S)-2,3-epoxysqualene + H2O

Direction not assertedBalancedRhea 31351

dimethyl sulfide + NADH + O2 + H(+) = methanethiol + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 31355

nitrilotriacetate + FMNH2 + O2 = aminodiacetate + FMN + glyoxylate + H2O

Direction not assertedBalancedRhea 31359

reduced coenzyme F420-(gamma-L-Glu)(n) + NADP(+) = oxidized coenzyme F420-(gamma-L-Glu)(n) + NADPH + 2 H(+)

Direction not assertedBalance undeterminableRhea 31363

3 nitrite + 2 H(+) = 2 nitric oxide + nitrate + H2O

Direction not assertedBalancedRhea 31367

(2R,3S)-2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine = (2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 31371

pyrrole-2-carboxylate + H(+) = 1H-pyrrole + CO2

Direction not assertedBalancedRhea 31375

pyrrole-2-carboxylate + H2O = 1H-pyrrole + hydrogencarbonate

Direction not assertedBalancedRhea 31379

(S)-2,3-epoxysqualene = lupeol

Direction not assertedBalancedRhea 31383

(S)-2,3-epoxysqualene = alpha-amyrin

Direction not assertedBalancedRhea 31387

15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+) = all-trans-4,4'-diapolycopene + 4 FADH2

Direction not assertedBalancedRhea 31391

15-cis-4,4'-diapophytoene + FAD + H(+) = all-trans-4,4'-diapophytofluene + FADH2

Direction not assertedBalancedRhea 31395

all-trans-4,4'-diapophytofluene + FAD + H(+) = all-trans-4,4'-diapo-zeta-carotene + FADH2

Direction not assertedBalancedRhea 31399

all-trans-4,4'-diapo-zeta-carotene + FAD + H(+) = all-trans-4,4'-diaponeurosporene + FADH2

Direction not assertedBalancedRhea 31403

all-trans-4,4'-diaponeurosporene + FAD + H(+) = all-trans-4,4'-diapolycopene + FADH2

Direction not assertedBalancedRhea 31407

a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 31411

(2Z,6E)-farnesyl diphosphate = (+)-2-epi-prezizaene + diphosphate

Direction not assertedBalancedRhea 31415

(2Z,6E)-farnesyl diphosphate = (-)-beta-curcumene + diphosphate

Direction not assertedBalancedRhea 31419

(2Z,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate

Direction not assertedBalancedRhea 31423

(2E,6E)-farnesyl diphosphate = (1S,5S,6R)-alpha-bergamotene + diphosphate

Direction not assertedBalancedRhea 31427

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