Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

16,701–16,750 of 31,435, by identifier

1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + CoA + H(+)
Direction not assertedBalancedRhea 26172
1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + L-cysteine + ATP = 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+)
Direction not assertedBalancedRhea 26176
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate
Direction not assertedBalancedRhea 26180
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H2O = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + phosphate
Direction not assertedBalancedRhea 26184
1D-myo-inositol 3-phosphate + UDP-N-acetyl-alpha-D-glucosamine = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H(+)
Direction not assertedBalancedRhea 26188
(S)-malate + ATP + CoA = (S)-malyl-CoA + ADP + phosphate

? Direction not asserted

Balanced

Rhea 26193

melamine + H2O = ammeline + NH4(+)

Direction not assertedBalancedRhea 26197

ammeline + H2O + H(+) = ammelide + NH4(+)

Direction not assertedBalancedRhea 26201

4-nitrophenol + NADPH + O2 + H(+) = 4-nitrocatechol + NADP(+) + H2O

Direction not assertedBalancedRhea 26205

L-allo-threonine = acetaldehyde + glycine

Left to rightBalancedRhea 26209

9alpha-copalyl diphosphate + H2O = aphidicolan-16beta-ol + diphosphate

Direction not assertedBalancedRhea 26213

abieta-7,13-diene + reduced [NADPH--hemoprotein reductase] + O2 = abieta-7,13-dien-18-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 26217

abieta-7,13-dien-18-ol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = abieta-7,13-dien-18-oate + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)

Direction not assertedBalance undeterminableRhea 26221

abieta-7,13-dien-18-al + NAD(+) + H2O = abieta-7,13-dien-18-oate + NADH + 2 H(+)

Direction not assertedBalancedRhea 26225

phytyl diphosphate + 3 NADP(+) = geranylgeranyl diphosphate + 3 NADPH + 3 H(+)

Direction not assertedBalancedRhea 26229

(2E,6E,10E)-geranylgeraniol + reduced [NADPH--hemoprotein reductase] + O2 = plaunotol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 26233

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = (2E,6E,10E)-geranylgeraniol + diphosphate

Direction not assertedBalancedRhea 26237

geranylgeranyl diphosphate = elisabethatriene + diphosphate

Direction not assertedBalancedRhea 26241

geranylgeranyl diphosphate = fusicocca-2,10(14)-diene + diphosphate

Direction not assertedBalancedRhea 26245

levopimaradienol + NADPH + O2 + H(+) = levopimaradienal + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 26249

isopimara-7,15-dienol + NADPH + O2 + H(+) = isopimara-7,15-dienal + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 26253

dehydroabietadienol + NADPH + O2 + H(+) = dehydroabietadienal + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 26257

isopimara-7,15-dienal + NADP(+) + H2O = isopimarate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 26261

dehydroabietadienal + NADP(+) + H2O = dehydroabietate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 26265

Co-precorrin-2 + 3 H(+) = precorrin-2 + Co(2+)

Direction not assertedBalancedRhea 26269

Co-precorrin-3 + S-adenosyl-L-methionine = Co-precorrin-4 + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 26273

Co-precorrin-4 + S-adenosyl-L-methionine = Co-precorrin-5A + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 26277

Co-precorrin-5A + H2O = Co-precorrin-5B + acetaldehyde + H(+)

Direction not assertedBalancedRhea 26281

Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 26285

cob(II)yrinate + 2 L-glutamine + 2 ATP + 2 H2O = cob(II)yrinate a,c diamide + 2 L-glutamate + 2 ADP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 26289

(1'S,5'S)-averufin + NADPH + O2 = 1'-hydroxyversicolorone + NADP(+) + H2O

Direction not assertedBalancedRhea 26293

[ThiS sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + 2-iminoacetate + 1-deoxy-D-xylulose 5-phosphate = [ThiS sulfur-carrier protein]-C-terminal Gly-Gly + 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 26297

5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2

Left to rightBalancedRhea 26301

2-aminophenol + O2 = 2-aminomuconate 6-semialdehyde

Direction not assertedBalancedRhea 26305

1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H(+)

Direction not assertedBalancedRhea 26309

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate = L-aspartate 4-semialdehyde + dihydroxyacetone phosphate

Direction not assertedBalancedRhea 26313

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate = 3-amino-4-hydroxybenzoate + phosphate + 2 H2O + H(+)

Direction not assertedBalancedRhea 26317

resorcinol + S-adenosyl-L-methionine = 3-methoxyphenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 26321

(8Z,11Z)-5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine = (8Z,11Z)-5-(pentadeca- 8,11,14-trien-1-yl)resorcinol-3-methyl ether + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 26325

(8S)-8-amino-7-oxononanoate + L-lysine = (7R,8S)-7,8-diammoniononanoate + (S)-2-amino-6-oxohexanoate

Direction not assertedBalancedRhea 26329

2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+)

Left to rightBalance undeterminableRhea 26333

S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H(+)

Direction not assertedBalancedRhea 26337

S-methyl-L-methionine + L-selenocysteine = Se-methyl-L-selenocysteine + L-methionine + H(+)

Direction not assertedBalancedRhea 26341

L-galactonate + NADP(+) = aldehydo-D-galacturonate + NADPH + H(+)

Direction not assertedBalancedRhea 26345

beta-L-galactose 1-phosphate + H2O = L-galactose + phosphate

Direction not assertedBalancedRhea 26349

L-tyrosine + S-adenosyl-L-methionine + NADPH = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+)

Direction not assertedBalancedRhea 26361

prostamide F2alpha + [thioredoxin]-disulfide = prostamide H2 + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 26373

GTP = cyclic pyranopterin phosphate + diphosphate

Direction not assertedBalancedRhea 26377

4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH + H(+)

Direction not assertedBalancedRhea 26381

all-trans-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + all-trans-retinal

Direction not assertedBalancedRhea 26385

Page 335 of 629