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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Reactions
Reach

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Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

16,601–16,650 of 31,435, by identifier

N,N-dihydroxy-L-tetrahomomethionine + H(+) = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O
Direction not assertedBalancedRhea 25731
L-pentahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 25735
N-hydroxy-L-pentahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 25739
N,N-dihydroxy-L-pentahomomethionine + H(+) = (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O
Direction not assertedBalancedRhea 25743
L-hexahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 25747
N-hydroxy-L-hexahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 25751

ent-copalyl diphosphate = ent-isokaurene + diphosphate

Direction not assertedBalancedRhea 25759

(2R,3S)-3-methylmalate + NAD(+) = 3-carboxy-2-oxobutanoate + NADH + H(+)

Direction not assertedBalancedRhea 25763

3-carboxy-2-oxobutanoate + H(+) = 2-oxobutanoate + CO2

Direction not assertedBalancedRhea 25767

L-asparagine + 2-oxoglutarate + O2 = (2S,3S)-3-hydroxyasparagine + succinate + CO2

Direction not assertedBalancedRhea 25772

scyllo-inosose = scyllo-inosine

Direction not assertedBalancedRhea 25776

UDP-N-acetyl-alpha-D-mannosamine + 2 NAD(+) + H2O = UDP-N-acetyl-alpha-D-mannosaminouronate + 2 NADH + 3 H(+)

Direction not assertedBalancedRhea 25780

2-dehydro-3-deoxy-L-rhamnonate = (S)-lactaldehyde + pyruvate

Direction not assertedBalancedRhea 25784

4-hydroxy-2-oxoheptanedioate = succinate semialdehyde + pyruvate

Direction not assertedBalancedRhea 25788

Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 25792

L-methionine + 2-oxoglutarate = 4-methylsulfanyl-2-oxobutanoate + L-glutamate

Direction not assertedBalancedRhea 25796

N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2

Direction not assertedBalancedRhea 25800

spermine + O2 + H2O = 3-aminopropanal + spermidine + H2O2

Direction not assertedBalancedRhea 25804

spermidine + O2 + H2O = 3-aminopropanal + putrescine + H2O2

Direction not assertedBalancedRhea 25808

N(1)-acetylspermidine + O2 + H2O = 3-acetamidopropanal + putrescine + H2O2

Direction not assertedBalancedRhea 25812

norspermine + O2 + H2O = norspermidine + 3-aminopropanal + H2O2

Direction not assertedBalancedRhea 25816

spermidine + O2 + H2O = 4-aminobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25820

spermine + O2 + H2O = N-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25824

an N-acyl-(4R)-4-hydroxysphinganine + AH2 + O2 = a (4R,8E)-4-hydroxysphingenine ceramide + A + 2 H2O

Direction not assertedBalance undeterminableRhea 25828

1D-chiro-inositol + NAD(+) = scyllo-inosine + NADH + H(+)

Direction not assertedBalancedRhea 25832

3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H(+)

Direction not assertedBalancedRhea 25836

5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate

Direction not assertedBalancedRhea 25840

(1S,5R)-carveol + NAD(+) = (R)-carvone + NADH + H(+)

Direction not assertedBalancedRhea 25844

(1S,5S)-carveol + NAD(+) = (S)-carvone + NADH + H(+)

Direction not assertedBalancedRhea 25848

an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an (11Z)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 25852

(9Z)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 25856

GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + diphosphate + H(+)

Direction not assertedBalancedRhea 25860

N(1)-acetylspermidine + O2 + H2O = 4-acetamidobutanal + propane-1,3-diamine + H2O2

Direction not assertedBalancedRhea 25864

N(1),N(12)-diacetylspermine + O2 + H2O = 3-acetamidopropanal + N(1)-acetylspermidine + H2O2

Direction not assertedBalancedRhea 25868

pyridine + H2O2 = pyridine N-oxide + H2O

Direction not assertedBalancedRhea 25872

L-aspartate + O2 = iminosuccinate + H2O2

Direction not assertedBalancedRhea 25876

2 L-dopa + O2 = 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)

Direction not assertedBalancedRhea 25880

N(2)-succinyl-L-ornithine + carbamoyl phosphate = N(2)-succinyl-L-citrulline + phosphate + H(+)

Direction not assertedBalancedRhea 25884

iminosuccinate + dihydroxyacetone phosphate = quinolinate + phosphate + 2 H2O + H(+)

Direction not assertedBalancedRhea 25888

malonate + H(+) = acetate + CO2

Direction not assertedBalancedRhea 25896

D-arabino-hex-3-ulose 6-phosphate = beta-D-fructose 6-phosphate

Direction not assertedBalancedRhea 25900

futalosine + H2O = dehypoxanthine futalosine + hypoxanthine

Direction not assertedBalancedRhea 25904

an alditol + O2 = an aldose + H2O2

Direction not assertedBalance undeterminableRhea 25908

quinolin-5-ol + A + H2O = 5-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25912

quinolin-6-ol + A + H2O = 6-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25916

quinolin-7-ol + A + H2O = 7-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25920

quinolin-8-ol + A + H2O = 8-hydroxyquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25924

3-methylquinoline + A + H2O = 3-methylquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25928

4-methylquinoline + A + H2O = 4-methylquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25932

8-methylquinoline + A + H2O = 8-methylquinolin-2(1H)-one + AH2

Direction not assertedBalancedRhea 25936

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