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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

16,101–16,150 of 31,435, by identifier

(R)-glycerate + ATP = (2R)-3-phosphoglycerate + ADP + H(+)
Direction not assertedBalancedRhea 23516
propanoate + acetyl-CoA = propanoyl-CoA + acetate
Direction not assertedBalancedRhea 23520
1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol = an alkyl cinnamate + beta-D-glucose
Direction not assertedBalance undeterminableRhea 23524
cholate + ATP + CoA = choloyl-CoA + AMP + diphosphate
Left to rightBalancedRhea 23532
alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
Direction not assertedBalancedRhea 23536
tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate
Left to rightBalancedRhea 23540
a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-alpha-D-glucose = a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP + H(+)

Direction not assertedBalance undeterminableRhea 23544

guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 23548

2-methylpropane-1,2-diol + NAD(+) = 2-hydroxy-2-methylpropanal + NADH + H(+)

Direction not assertedBalancedRhea 23552

D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4(+)

Direction not assertedBalancedRhea 23556

alpha-ribazole 5'-phosphate + adenosylcob(III)inamide-GDP = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)

Direction not assertedBalancedRhea 23560

2 columbamine + O2 = 2 berberine + 2 H2O

Direction not assertedBalancedRhea 23564

(2E)-decenoyl-[ACP] = (3Z)-decenoyl-[ACP]

Direction not assertedBalance undeterminableRhea 23568

3-methylbutanoyl-CoA + 3 malonyl-CoA + 3 H(+) = phlorisovalerophenone + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 23572

(R)-N-methylcoclaurine + (S)-N-methylcoclaurine + reduced [NADPH--hemoprotein reductase] + O2 = berbamunine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 23576

prostaglandin H2 = prostaglandin I2

Left to rightBalancedRhea 23580

7,8-dihydropteroate + L-glutamate + ATP = 7,8-dihydrofolate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 23584

oxalate + succinyl-CoA = oxalyl-CoA + succinate

Direction not assertedBalancedRhea 23588

glycerol + NADP(+) = D-glyceraldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 23592

UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)

Direction not assertedBalancedRhea 23596

L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate

Direction not assertedBalancedRhea 23600

kievitone hydrate = kievitone + H2O

Direction not assertedBalancedRhea 23604

N-isopropylammelide + H2O + H(+) = isopropylamine + cyanurate

Direction not assertedBalancedRhea 23608

1,2-dihydro-alpha-santonin + NAD(+) = alpha-santonin + NADH + H(+)

Direction not assertedBalancedRhea 23612

1,2-dihydro-alpha-santonin + NADP(+) = alpha-santonin + NADPH + H(+)

Direction not assertedBalancedRhea 23616

N(2)-(2-carboxyethyl)-L-arginine + ATP = deoxyamidinoproclavaminate + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 23620

a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 23624

a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = a beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)

Left to rightBalance undeterminableRhea 23628

D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH

Left to rightBalancedRhea 23632

1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = ethene + L-dehydroascorbate + hydrogen cyanide + CO2 + 2 H2O

Direction not assertedBalancedRhea 23640

lithocholate + reduced [NADPH--hemoprotein reductase] + O2 = hyodeoxycholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 23644

dTDP-6-deoxy-beta-L-talose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + NADPH + H(+)

Direction not assertedBalancedRhea 23648

N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)

Direction not assertedBalance undeterminableRhea 23652

2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+)

Direction not assertedBalancedRhea 23656

4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate

Direction not assertedBalancedRhea 23660

a (2R)-2-hydroxycarboxylate + A = a 2-oxocarboxylate + AH2

Direction not assertedBalance undeterminableRhea 23664

apo-[methylmalonyl-CoA:pyruvate carboxytransferase] + biotin + ATP = holo-[methylmalonyl-CoA:pyruvate carboxytransferase] + AMP + diphosphate + H(+)

Left to rightBalance undeterminableRhea 23668

L-quinate + a quinone = 3-dehydroquinate + a quinol

Direction not assertedBalance undeterminableRhea 23672

UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + meso-2,6-diaminopimelate + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 23676

a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+)

Left to rightBalance undeterminableRhea 23680

(S)-cis-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = allocryptopine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 23684

adenine + H2O + H(+) = hypoxanthine + NH4(+)

Direction not assertedBalancedRhea 23688

(R)-malate = maleate + H2O

Direction not assertedBalancedRhea 23692

myo-inositol + O2 = D-glucuronate + H2O + H(+)

Direction not assertedBalancedRhea 23696

(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+)

Direction not assertedBalancedRhea 23700

GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)

Direction not assertedBalancedRhea 23704

[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans,octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 23708

pregnan-21-ol + NADP(+) = pregnan-21-al + NADPH + H(+)

Direction not assertedBalancedRhea 23712

(3Z)-dodecenoyl-CoA = (2E)-dodecenoyl-CoA

Left to rightBalancedRhea 23716

propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+)

Left to rightBalancedRhea 23720

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