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4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[r] + NADP+[r] = 3-keto-4-methylzymosterol[r] + CO2[r] + H+[r] + NADPH[r]
Left to rightBalancedEC 1.1.1.170Cholesterol metabolismHuman-GEM MAR00113
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[r] + NAD+[r] = 3-keto-4-methylzymosterol[r] + CO2[r] + H+[r] + NADH[r]
Left to rightBalancedEC 1.1.1.170Cholesterol metabolismHuman-GEM MAR00114
H+[r] + NADPH[r] + Zymosterol Intermediate 2[r] = NADP+[r] + zymosterol[r]
Left to rightBalancedEC 4.2.1.17Cholesterol metabolismHuman-GEM MAR00115
14-demethyllanosterol[r] + 3 H+[r] + 3 NADPH[r] + 3 O2[r] = 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol[r] + 4 H2O[r] + 3 NADP+[r]
Left to rightBalancedEC 4.2.1.17Cholesterol metabolism
3-keto-4-methylzymosterol[r] + NADP+[r] + O2[r] = CO2[r] + H+[r] + NADPH[r] + Zymosterol Intermediate 2[r]
Left to rightBalancedEC 1.1.1.170Cholesterol metabolismHuman-GEM MAR00117
3-keto-4-methylzymosterol[r] + NAD+[r] + O2[r] = CO2[r] + H+[r] + NADH[r] + Zymosterol Intermediate 2[r]
Left to rightBalancedCholesterol metabolismHuman-GEM MAR00118
ATP[c] + Ca2+[c] + H2O[c] = ADP[c] + Ca2+[e] + H+[e] + Pi[c]
Left to rightBalancedTransportEC 7.1.2.1Transport reactionsHuman-GEM MAR00119
CDP-diacylglycerol-LD-PI pool[c] = CDP-diacylglycerol-LD-PI pool[m]
ReversibleBalance undeterminableTransportEC 1.1.1.197Transport reactionsHuman-GEM MAR00120
CTP[c] + H+[c] + phosphatidate-LD-PI pool[c] = CDP-diacylglycerol-LD-PI pool[c] + PPi[c]
Left to rightBalance undeterminableEC 2.7.7.41Glycerophospholipid metabolismHuman-GEM MAR00121
CTP[m] + H+[m] + phosphatidate-LD-PI pool[m] = CDP-diacylglycerol-LD-PI pool[m] + PPi[m]
Left to rightBalance undeterminableEC 2.7.7.41Glycerophospholipid metabolismHuman-GEM MAR00122
cholesterol[r] = cholesterol[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR00123
citrulline[m] = citrulline[c]
ReversibleBalancedTransportEC 3.2.1.14Transport reactionsHuman-GEM MAR00124
citrate[c] + malate[m] = citrate[m] + malate[c]
ReversibleBalancedTransportEC 4.2.1.56Transport reactionsHuman-GEM MAR00125
2 chloride[e] + H2O[c] = 2 chloride[c] + H2O[e]
Left to rightBalancedTransportEC 2.7.3.2Transport reactionsHuman-GEM MAR00126
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[c] = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[x]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR00127
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoylcarnitine[c] = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoylcarnitine[m]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR00128
CDP-diacylglycerol-CL pool[c] + PG-CL pool[c] = CL pool[c] + CMP[c] + H+[c]
Left to rightBalance undeterminableEC 2.3.1.21Glycerophospholipid metabolismHuman-GEM MAR00129
CO2[n] = CO2[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR00130
SAM[m] + 2-Decaprenyl-5-Hydroxy-6-Methoxy-3-Methyl-1,4-Benzoquinone[m] = H+[m] + SAH[m] + ubiquinone[m]
Left to rightBalancedEC 2.1.1.-Ubiquinone synthesisHuman-GEM MAR00131
SAM[m] + 2-Decaprenyl-6-Methoxy-1,4-Benzoquinone[m] = H+[m] + SAH[m] + 2-Decaprenyl-6-Methoxy-3-Methyl-1,4-Benzoquinone[m]
Left to rightBalancedUbiquinone synthesisHuman-GEM MAR00132
2-methoxy-6-(all-trans-decaprenyl)phenol[m] + O2[m] = H2O[m] + 2-Decaprenyl-6-Methoxy-1,4-Benzoquinone[m]
Left to rightBalancedEC 1.14.15.-Ubiquinone synthesisHuman-GEM MAR00133
H+[m] + NADPH[m] + O2[m] + 2-Decaprenyl-6-Methoxy-3-Methyl-1,4-Benzoquinone[m] = H2O[m] + NADP+[m] + 2-Decaprenyl-5-Hydroxy-6-Methoxy-3-Methyl-1,4-Benzoquinone[m]
Left to rightBalancedEC 3.1.1.1Ubiquinone synthesisHuman-GEM MAR00134
4-coumarate[m] + ATP[m] + CoA[m] = 4-coumaroyl-CoA[m] + AMP[m] + PPi[m]
Left to rightBalancedEC 6.2.1.12Ubiquinone synthesisHuman-GEM MAR00135
ceramide-1P pool[c] = ceramide-1P pool[e]
ReversibleBalance undeterminableTransportEC 2.7.7.15Transport reactionsHuman-GEM MAR00136
H+[e] + L-carnitine[c] = H+[c] + L-carnitine[e]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR00137
4,8-dimethylnonanoylcarnitine[x] = 4,8-dimethylnonanoylcarnitine[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR00138
L-carnitine[x] + 4,8-dimethylnonanoyl-CoA[x] = 4,8-dimethylnonanoylcarnitine[x] + CoA[x]
ReversibleBalancedEC 2.3.1.7Fatty acid oxidationHuman-GEM MAR00139
1,2-diacylglycerol-LD-TAG pool[r] = 1,2-diacylglycerol-LD-TAG pool[c]
Left to rightBalance undeterminableTransportEC 3.5.4.4Transport reactionsHuman-GEM MAR00140
1,2-diacylglycerol-LD-TAG pool[n] + ATP[n] = ADP[n] + H+[n] + phosphatidate-LD-TAG pool[n]
ReversibleBalance undeterminableEC 2.7.1.107Glycerophospholipid metabolismHuman-GEM MAR00141
1,2-diacylglycerol-LD-TAG pool[e] = 1,2-diacylglycerol-LD-TAG pool[c]
ReversibleBalance undeterminableTransportEC 2.7.1.107Transport reactionsHuman-GEM MAR00142
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoylcarnitine[c] = (4Z,7Z,10Z,13Z,16Z)-docosapentaenoylcarnitine[m]
ReversibleBalancedTransportEC 3.5.4.12Fatty acid oxidationHuman-GEM MAR00143
H+[c] + NADH[c] + O2[c] + palmitoyl-CoA[c] = 2 H2O[c] + NAD+[c] + palmitoleoyl-CoA[c]
Left to rightBalancedEC 1.14.19.1Fatty acid biosynthesisHuman-GEM MAR00144
H+[c] + linolenoyl-CoA[c] + NADH[c] + O2[c] = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.1Fatty acid biosynthesisHuman-GEM MAR00145
H+[c] + NADH[c] + O2[c] + stearoyl-CoA[c] = 2 H2O[c] + NAD+[c] + oleoyl-CoA[c]
Left to rightBalancedEC 1.14.19.1Fatty acid biosynthesisHuman-GEM MAR00146
H+[c] + NADH[c] + O2[c] + stearoyl-CoA[c] = 2 H2O[c] + NAD+[c] + 11-octadecenoyl-CoA[c]
Left to rightBalancedEC 1.14.19.1Fatty acid biosynthesisHuman-GEM MAR00147
H+[c] + NADH[c] + O2[c] + stearoyl-CoA[c] = (2E)-octadecenoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.1Fatty acid biosynthesisHuman-GEM MAR00148
H+[c] + NADH[c] + O2[c] + oleoyl-CoA[c] = (6Z,9Z)-octadecadienoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.3Fatty acid biosynthesisHuman-GEM MAR00149
H+[c] + NADH[c] + O2[c] + 11-octadecenoyl-CoA[c] = (6Z,9Z)-octadecadienoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.1Fatty acid biosynthesisHuman-GEM MAR00150
(2E)-octadecenoyl-CoA[c] + H+[c] + NADH[c] + O2[c] = (6Z,9Z)-octadecadienoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.3Fatty acid biosynthesisHuman-GEM MAR00151
H+[c] + linoleoyl-CoA[c] + NADH[c] + O2[c] = gamma-linolenoyl-CoA[c] + 2 H2O[c] + NAD+[c]
Left to rightBalancedEC 1.14.19.3Fatty acid biosynthesisHuman-GEM MAR00152
ATP[c] + CoA[c] + propanoate[c] = AMP[c] + PPi[c] + propanoyl-CoA[c]
Left to rightBalancedEC 6.2.1.17, 6.2.1.1, 3.1.2.2Propanoate metabolismHuman-GEM MAR00153
H2O[c] + propanoyl-CoA[c] = CoA[c] + H+[c] + propanoate[c]
Left to rightBalancedEC 3.1.2.2Acyl-CoA hydrolysisHuman-GEM MAR00154
butyrate[e] = butyrate[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR00155
ATP[c] + butyrate[c] + CoA[c] = AMP[c] + butyryl-CoA[c] + PPi[c]
Left to rightBalancedEC 6.2.1.2Fatty acid activation (cytosolic)Human-GEM MAR00156
butyryl-CoA[c] = butyryl-CoA[m]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR00157
butyryl-CoA[m] + L-carnitine[c] = butyryl-CoA[c] + L-carnitine[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR00158
butyryl-CoA[c] + L-carnitine[c] = CoA[c] + O-butanoylcarnitine[c]
ReversibleBalancedEC 2.3.1.21Carnitine shuttle (cytosolic)Human-GEM MAR00159
L-carnitine[c] + O-butanoylcarnitine[m] = L-carnitine[m] + O-butanoylcarnitine[c]
ReversibleBalancedTransportCarnitine shuttle (mitochondrial)Human-GEM MAR00160
CoA[m] + O-butanoylcarnitine[m] = butyryl-CoA[m] + L-carnitine[m]
ReversibleBalancedEC 2.3.1.7Carnitine shuttle (mitochondrial)Human-GEM MAR00161
L-carnitine[m] + L-octanoylcarnitine[c] = L-carnitine[c] + L-octanoylcarnitine[m]
ReversibleBalancedTransportCarnitine shuttle (mitochondrial)Human-GEM MAR00162