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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

14,151–14,200 of 31,435, by identifier

5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose = demethyllactenocin + dTDP + H(+)
Direction not assertedBalancedRhea 15357
a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-xylose = a di-trans,poly-cis-dolichyl D-xylosyl phosphate + UDP
Direction not assertedBalance undeterminableRhea 15361
3-O-[(D-ribitylphospho)2-3-N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-O-6-phospho-alpha-D-mannosyl]-L-seryl-[protein] + UDP-alpha-D-xylose = 3-O-[beta-D-xylosyl-(1->4)-(D-ribitylphospho)2-3-N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-O-6-phospho-alpha-D-mannosyl]-L-seryl-[protein] + UDP + H(+)
Direction not assertedBalance undeterminableRhea 15365
2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H(+)
Direction not assertedBalancedRhea 15369
columbamine + S-adenosyl-L-methionine = palmatine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 15373
(S)-4,5-dihydroxypentane-2,3-dione + ATP = (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H(+)

Direction not assertedBalancedRhea 15377

quercetin + O2 = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO

Direction not assertedBalancedRhea 15381

L-asparagine = 3-cyano-L-alanine + H2O

Direction not assertedBalancedRhea 15385

ATP = 3',5'-cyclic AMP + diphosphate

Direction not assertedBalancedRhea 15389

(2S,6S)-2,6-diaminopimelate = meso-2,6-diaminopimelate

Direction not assertedBalancedRhea 15393

dichloromethane + H2O = formaldehyde + 2 chloride + 2 H(+)

Direction not assertedBalancedRhea 15397

a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP

Left to rightBalance undeterminableRhea 15401

(3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) = [(3R)-hydroxybutanoate](n+1) + CoA

Direction not assertedBalance undeterminableRhea 15405

a 1-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphoethanolamine = a 1-O-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a 1-O-alkyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 15409

(2R,3R)-tartrate = oxaloacetate + H2O

Direction not assertedBalancedRhea 15413

L-arogenate + NADP(+) = L-tyrosine + CO2 + NADPH

Direction not assertedBalancedRhea 15417

a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate

Left to rightBalance undeterminableRhea 15421

coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 5'-deoxyadenosine + 2 L-methionine + 2 CO2

Direction not assertedBalancedRhea 15425

2 reduced [flavodoxin] + heme b + 2 S-adenosyl-L-methionine = anaerobilin + 2 oxidized [flavodoxin] + Fe(2+) + 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 15429

(2S)-naringenin + dimethylallyl diphosphate = sophoraflavanone B + diphosphate

Direction not assertedBalancedRhea 15433

a long-chain fatty aldehyde + NADP(+) + CoA = a long-chain fatty acyl-CoA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 15437

O-carbamoyl-L-serine + H2O + H(+) = pyruvate + 2 NH4(+) + CO2

Direction not assertedBalancedRhea 15445

homogentisate + O2 = 4-maleylacetoacetate + H(+)

Left to rightBalancedRhea 15449

sarcosine + S-adenosyl-L-methionine = N,N-dimethylglycine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15453

cis-1,2-dihydrobenzene-1,2-diol + NAD(+) = catechol + NADH + H(+)

Direction not assertedBalancedRhea 15457

alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 15461

sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)

Left to rightBalancedRhea 15465

1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide

Direction not assertedBalancedRhea 15469

flavanone 7-O-beta-D-glucoside + UDP-beta-L-rhamnose = flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] + UDP + H(+)

Direction not assertedBalancedRhea 15473

5beta-scymnol + 3'-phosphoadenylyl sulfate = 5beta-scymnol sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 15477

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine

ReversibleBalancedRhea 15481

(2R,3S)-homoisocitrate = cis-homoaconitate + H2O

Direction not assertedBalancedRhea 15485

adenosine + 2 O2 + H2O = 9-riburonosyladenine + 2 H2O2 + H(+)

Direction not assertedBalancedRhea 15489

1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine

Direction not assertedBalancedRhea 15497

2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH + H(+)

Direction not assertedBalancedRhea 15501

(S)-2-hydroxymethylglutarate + NAD(+) = 2-formylglutarate + NADH + H(+)

Direction not assertedBalancedRhea 15505

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 15509

keto-D-tagatose + ATP = keto-D-tagatose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 15513

N(2),6-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + sulfate + H(+)

Direction not assertedBalancedRhea 15517

N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 15521

bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+)

Direction not assertedBalancedRhea 15529

(2R)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + NADH + H(+)

Direction not assertedBalancedRhea 15533

(2R)-3-sulfolactate + NADP(+) = 3-sulfopyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 15537

DIMBOA + UDP-alpha-D-glucose = DIMBOA beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 15541

(3S)-citramalate = acetate + pyruvate

Direction not assertedBalancedRhea 15545

5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O

Direction not assertedBalancedRhea 15549

1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate

Left to rightBalancedRhea 15553

Ni(2+)(out) + ATP + H2O = Ni(2+)(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 15557

sterigmatocystin + S-adenosyl-L-methionine = 8-O-methylsterigmatocystin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15561

an N-acyl-L-amino acid + H2O = an L-alpha-amino acid + a carboxylate

ReversibleBalance undeterminableRhea 15565

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