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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

14,051–14,100 of 31,435, by identifier

all-trans-antheraxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = all-trans-violaxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 14937
a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP + H(+)
Direction not assertedBalance undeterminableRhea 14945
quinoline-4-carboxylate + A + H2O = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH2
Direction not assertedBalancedRhea 14949
S-formylglutathione + H2O = formate + glutathione + H(+)
Direction not assertedBalancedRhea 14961
an acyl phosphate + H2O = a carboxylate + phosphate + H(+)
Left to rightBalance undeterminableRhea 14965
trans-aconitate + S-adenosyl-L-methionine = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 14969

L-aspartate = D-aspartate

Direction not assertedBalancedRhea 14973

3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate

Direction not assertedBalancedRhea 14977

testosterone + NADP(+) = androst-4-ene-3,17-dione + NADPH + H(+)

Right to leftBalancedRhea 14981

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 14985

n malonyl-CoA + acetyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + n CO2 + 2n NADP(+) + (n+1) CoA

Direction not assertedBalance undeterminableRhea 14993

deoxylimonoate + H2O = deoxylimononate D-ring-lactone + H(+)

Direction not assertedBalancedRhea 14997

keto-L-sorbose + NADP(+) = 5-dehydro-D-fructose + NADPH + H(+)

Direction not assertedBalancedRhea 15001

gibberellin A1 + 2-oxoglutarate + O2 = gibberellin A8 + succinate + CO2

Direction not assertedBalancedRhea 15005

(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH + H(+)

Right to leftBalancedRhea 15009

3alpha(S)-strictosidine + H2O = secologanin + tryptamine

Direction not assertedBalancedRhea 15013

a phosphate monoester + H2O = an alcohol + phosphate

Left to rightBalance undeterminableRhea 15017

L-quinate + (E)-feruloyl-CoA = 4-O-feruloyl-D-quinate + CoA

Direction not assertedBalancedRhea 15021

xanthosine + S-adenosyl-L-methionine = 7-methylxanthosine + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 15025

D-mannitol + NAD(+) = D-mannose + NADH + H(+)

Direction not assertedBalancedRhea 15029

pyridoxine + O2 = pyridoxal + H2O2

Direction not assertedBalancedRhea 15033

putrescine + S-adenosyl-L-methionine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15037

bis-D-fructose 2',1:2,1'-dianhydride + H2O = inulobiose

Direction not assertedBalancedRhea 15041

N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)

Left to rightBalance undeterminableRhea 15045

GDP-alpha-D-glucose + H2O = D-glucose + GDP + H(+)

Direction not assertedBalancedRhea 15049

N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)

Left to rightBalancedRhea 15053

(9Z)-octadecenoyl-[ACP] + H2O = (9Z)-octadecenoate + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 15057

2 a Fe(II)-siderophore + NAD(+) + H(+) = 2 a Fe(III)-siderophore + NADH

Direction not assertedBalancedRhea 15061

N(4)-benzoylagmatine + H2O = benzoate + agmatine

Direction not assertedBalancedRhea 15065

3-devinyl-3-(1-hydroxyethyl)chlorophyllide a = chlorophyllide a + H2O

Direction not assertedBalancedRhea 15069

3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine + H2O = N(2),6-disulfo-D-glucosamine + D-glucuronate

Direction not assertedBalancedRhea 15073

N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO2

Direction not assertedBalancedRhea 15077

acetate + ATP + CoA = acetyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 15081

an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O = an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + N-acetyl-D-galactosamine

Direction not assertedBalance undeterminableRhea 15085

(R)-lactate + A = pyruvate + AH2

Direction not assertedBalancedRhea 15089

L-tyrosine + 2-oxoglutarate = 3-(4-hydroxyphenyl)pyruvate + L-glutamate

Direction not assertedBalancedRhea 15093

5-formimidoyltetrahydrofolate + L-glutamate = N-formimidoyl-L-glutamate + (6S)-5,6,7,8-tetrahydrofolate

Right to leftBalancedRhea 15097

meso-2,6-diaminopimelate + H(+) = L-lysine + CO2

Direction not assertedBalancedRhea 15101

kaempferol + S-adenosyl-L-methionine = kaempferide + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15105

2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H(+)

Direction not assertedBalancedRhea 15109

5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = 5alpha-cholestane-3beta,5,6beta-triol

Left to rightBalancedRhea 15113

3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine

Direction not assertedBalancedRhea 15117

dithioerythritol + thiosulfate = cis-1,2-dithiane-4,5-diol + hydrogen sulfide + sulfite + 2 H(+)

Direction not assertedBalancedRhea 15121

alpha-D-glucosaminyl-[heparan sulfate](n) + acetyl-CoA = N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) + CoA + H(+)

Direction not assertedBalance undeterminableRhea 15125

(4S)-limonene + reduced [NADPH--hemoprotein reductase] + O2 = (1S,6R)-isopiperitenol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 15129

L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 15133

galactitol 1-phosphate + NAD(+) = keto-L-tagatose 6-phosphate + NADH + H(+)

Direction not assertedBalancedRhea 15137

4-methylphenol + 4 oxidized [azurin] + H2O = 4 reduced [azurin] + 4-hydroxybenzaldehyde + 4 H(+)

Direction not assertedBalance undeterminableRhea 15141

D-maltose = alpha,alpha-trehalose

Direction not assertedBalancedRhea 15145

pyridoxine 5'-phosphate + O2 = pyridoxal 5'-phosphate + H2O2

Left to rightBalancedRhea 15149

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